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The HIV epidemic in Southern Africa: is an AIDS-free generation possible?

(2014) CURRENT HIV/AIDS REPORTS. 11(2). p.99-108
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Abstract
Southern Africa, home to about 20 % of the global burden of infection continues to experience high rates of new HIV infection despite substantial programmatic scale-up of treatment and prevention interventions. While several countries in the region have had substantial reductions in HIV infection, almost half a million new infections occurred in this region in 2012. Sexual transmission remains the dominant mode of transmission. A recent national household survey in Swaziland revealed an HIV prevalence of 14.3 % among 1819 year old girls, compared to 0.8 % among their male peers. Expanded ART programmes in Southern Africa have resulted in dramatically decreased HIV incidence and HIV mortality rates. In South Africa alone, it is estimated that more than 2.1 million of the 6.1 million HIV-positive people were receiving ART by the end of 2012, and that this resulted in more than 2.7 million life-years saved, and hundreds of thousands of HIV infections averted. Biological, behavioural and structural factors all contribute to the ongoing high rates of new HIV infection; however, as the epidemic matures and mortality is reduced from increased ART coverage, epidemiological trends become hard to quantify. What is clear is that a key driver of the Southern African epidemic is the high incidence rate of infection in young women, a vulnerable population with limited prevention options. Moreover, whilst ongoing trials of combination prevention, microbicides and behavioural economics hold promise for further epidemic control, an AIDS-free generation will not be realised unless incident infections in key populations are reduced.
Keywords
HIV-positive, ART, Infection, Microbicides, Combination prevention, AIDS-free generation, Southern Africa, Global epidemic, AIDS, SouthAfrica, Review, CLUSTER-RANDOMIZED-TRIAL, SUB-SAHARAN AFRICA, ANTIRETROVIRAL TREATMENT, YOUNG-WOMEN, SCALE-UP, PREVENTION, TRANSMISSION, THERAPY, HEALTH, SEX

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Citation

Please use this url to cite or link to this publication:

MLA
Delva, Wim, and Quarraisha Abdool Karim. “The HIV Epidemic in Southern Africa: Is an AIDS-free Generation Possible?” CURRENT HIV/AIDS REPORTS 11.2 (2014): 99–108. Print.
APA
Delva, W., & Karim, Q. A. (2014). The HIV epidemic in Southern Africa: is an AIDS-free generation possible? CURRENT HIV/AIDS REPORTS, 11(2), 99–108.
Chicago author-date
Delva, Wim, and Quarraisha Abdool Karim. 2014. “The HIV Epidemic in Southern Africa: Is an AIDS-free Generation Possible?” Current Hiv/aids Reports 11 (2): 99–108.
Chicago author-date (all authors)
Delva, Wim, and Quarraisha Abdool Karim. 2014. “The HIV Epidemic in Southern Africa: Is an AIDS-free Generation Possible?” Current Hiv/aids Reports 11 (2): 99–108.
Vancouver
1.
Delva W, Karim QA. The HIV epidemic in Southern Africa: is an AIDS-free generation possible? CURRENT HIV/AIDS REPORTS. 2014;11(2):99–108.
IEEE
[1]
W. Delva and Q. A. Karim, “The HIV epidemic in Southern Africa: is an AIDS-free generation possible?,” CURRENT HIV/AIDS REPORTS, vol. 11, no. 2, pp. 99–108, 2014.
@article{5857027,
  abstract     = {Southern Africa, home to about 20 % of the global burden of infection continues to experience high rates of new HIV infection despite substantial programmatic scale-up of treatment and prevention interventions. While several countries in the region have had substantial reductions in HIV infection, almost half a million new infections occurred in this region in 2012. Sexual transmission remains the dominant mode of transmission. A recent national household survey in Swaziland revealed an HIV prevalence of 14.3 % among 1819 year old girls, compared to 0.8 % among their male peers. Expanded ART programmes in Southern Africa have resulted in dramatically decreased HIV incidence and HIV mortality rates. In South Africa alone, it is estimated that more than 2.1 million of the 6.1 million HIV-positive people were receiving ART by the end of 2012, and that this resulted in more than 2.7 million life-years saved, and hundreds of thousands of HIV infections averted. Biological, behavioural and structural factors all contribute to the ongoing high rates of new HIV infection; however, as the epidemic matures and mortality is reduced from increased ART coverage, epidemiological trends become hard to quantify. What is clear is that a key driver of the Southern African epidemic is the high incidence rate of infection in young women, a vulnerable population with limited prevention options. Moreover, whilst ongoing trials of combination prevention, microbicides and behavioural economics hold promise for further epidemic control, an AIDS-free generation will not be realised unless incident infections in key populations are reduced.},
  author       = {Delva, Wim and Karim, Quarraisha Abdool},
  issn         = {1548-3568},
  journal      = {CURRENT HIV/AIDS REPORTS},
  keywords     = {HIV-positive,ART,Infection,Microbicides,Combination prevention,AIDS-free generation,Southern Africa,Global epidemic,AIDS,SouthAfrica,Review,CLUSTER-RANDOMIZED-TRIAL,SUB-SAHARAN AFRICA,ANTIRETROVIRAL TREATMENT,YOUNG-WOMEN,SCALE-UP,PREVENTION,TRANSMISSION,THERAPY,HEALTH,SEX},
  language     = {eng},
  number       = {2},
  pages        = {99--108},
  title        = {The HIV epidemic in Southern Africa: is an AIDS-free generation possible?},
  url          = {http://dx.doi.org/10.1007/s11904-014-0205-0},
  volume       = {11},
  year         = {2014},
}

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