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Treatment of respiratory sleep disorders

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Abstract
This chapter deals with different therapeutic approaches to sleep disturbances characterized by sleep-disordered breathing (SDB). General recommendations and conservative measures are crucial first steps in the management of SDB. Pharmacological agents have no major role in the treatment of obstructive sleep apnoea (OSA), but do have certain indications in patients with central sleep apnoea (CSA), especially in those suffering from heart failure. Treatment with oral devices has become a cornerstone in the management of patients with mild to moderate OSA, and may also be helpful in selected patients with severe disease. Positive airway pressure (PAP) continues to be the mainstay of treatment of OSA patients with moderate to severe disease. Bilevel PAP is indicated as a therapy for respiratory failure (alveolar hypoventilation with hypercapnia). Adaptive servo-ventilation has been introduced as a specific treatment of cardiac patients with CSA and Cheyne-Stokes respiration, but may as well be used in other conditions associated with CSA. Surgery of the upper airways or of the maxillo-mandibular skeleton is performed in selected OSA patients. Bariatric surgery is a therapy indicated in morbidly obese patients with OSA who fail to lose weight with conservative measures such as hypocaloric diet and exercise training.
Keywords
sleep, treatment, sleep apnea

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Chicago
Pevernagie, Dirk, Manu Sastry, and Olivier Vanderveken. 2014. “Treatment of Respiratory Sleep Disorders.” In Sleep Medicine Textbook, ed. Claudio Bassetti, Zoran Dogas, and Philippe Peigneux, 259–274. Regensburg, Germany: European Sleep Research Society (ESRS).
APA
Pevernagie, D., Sastry, M., & Vanderveken, O. (2014). Treatment of respiratory sleep disorders. In C. Bassetti, Z. Dogas, & P. Peigneux (Eds.), Sleep medicine textbook (pp. 259–274). Regensburg, Germany: European Sleep Research Society (ESRS).
Vancouver
1.
Pevernagie D, Sastry M, Vanderveken O. Treatment of respiratory sleep disorders. In: Bassetti C, Dogas Z, Peigneux P, editors. Sleep medicine textbook. Regensburg, Germany: European Sleep Research Society (ESRS); 2014. p. 259–74.
MLA
Pevernagie, Dirk, Manu Sastry, and Olivier Vanderveken. “Treatment of Respiratory Sleep Disorders.” Sleep Medicine Textbook. Ed. Claudio Bassetti, Zoran Dogas, & Philippe Peigneux. Regensburg, Germany: European Sleep Research Society (ESRS), 2014. 259–274. Print.
@incollection{5841388,
  abstract     = {This chapter deals with different therapeutic approaches to sleep disturbances characterized by sleep-disordered breathing (SDB). General recommendations and conservative measures are crucial first steps in the management of SDB. Pharmacological agents have no major role in the treatment of obstructive sleep apnoea (OSA), but do have certain indications in patients with central sleep apnoea (CSA), especially in those suffering from heart failure. Treatment with oral devices has become a cornerstone in the management of patients with mild to moderate OSA, and may also be helpful in selected patients with severe disease. Positive airway pressure (PAP) continues to be the mainstay of treatment of OSA patients with moderate to severe disease. Bilevel PAP is indicated as a therapy for respiratory failure (alveolar hypoventilation with hypercapnia). Adaptive servo-ventilation has been introduced as a specific treatment of cardiac patients with CSA and Cheyne-Stokes respiration, but may as well be used in other conditions associated with CSA. Surgery of the upper airways or of the maxillo-mandibular skeleton is performed in selected OSA patients. Bariatric surgery is a therapy indicated in morbidly obese patients with OSA who fail to lose weight with conservative measures such as hypocaloric diet and exercise training.},
  author       = {Pevernagie, Dirk and Sastry, Manu and Vanderveken, Olivier},
  booktitle    = {Sleep medicine textbook},
  editor       = {Bassetti, Claudio and Dogas, Zoran and Peigneux, Philippe},
  isbn         = {9781119038931},
  keyword      = {sleep,treatment,sleep apnea},
  language     = {eng},
  pages        = {259--274},
  publisher    = {European Sleep Research Society (ESRS)},
  title        = {Treatment of respiratory sleep disorders},
  year         = {2014},
}