Mononuclear phagocytes of the intestine, the skin, and the lung
- Author
- Charlotte Scott (UGent) , Sandrine Henri and Martin Guilliams (UGent)
- Organization
- Abstract
- Tissues that are in direct contact with the outside world face particular immunological challenges. The intestine, the skin, and the lung possess important mononuclear phagocyte populations to deal with these challenges, but the cellular origin of these phagocytes is strikingly different from one subset to another, with some cells derived from embryonic precursors and some from bone marrow-derived circulating monocytes. Here, we review the current knowledge regarding the developmental pathways that control the differentiation of mononuclear phagocytes in these barrier tissues. We have also attempted to build a theoretical model that could explain the distinct cellular origin of mononuclear phagocytes in these tissues.
- Keywords
- monocyte, macrophage, mononuclear phagocyte, dendritic cell, intestine, skin, lung, DENDRITIC CELL-DEVELOPMENT, RESIDENT ALVEOLAR MACROPHAGES, SINUSOIDAL ENDOTHELIAL-CELLS, PERIPHERAL LYMPHOID ORGANS, TRANSCRIPTION FACTOR E2-2, HEMATOPOIETIC STEM-CELLS, STIMULATING FACTOR-I, REGULATORY T-CELLS, LANGERHANS CELLS, LAMINA PROPRIA
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-5839453
- MLA
- Scott, Charlotte, et al. “Mononuclear Phagocytes of the Intestine, the Skin, and the Lung.” IMMUNOLOGICAL REVIEWS, vol. 262, no. 1, 2014, pp. 9–24, doi:10.1111/imr.12220.
- APA
- Scott, C., Henri, S., & Guilliams, M. (2014). Mononuclear phagocytes of the intestine, the skin, and the lung. IMMUNOLOGICAL REVIEWS, 262(1), 9–24. https://doi.org/10.1111/imr.12220
- Chicago author-date
- Scott, Charlotte, Sandrine Henri, and Martin Guilliams. 2014. “Mononuclear Phagocytes of the Intestine, the Skin, and the Lung.” IMMUNOLOGICAL REVIEWS 262 (1): 9–24. https://doi.org/10.1111/imr.12220.
- Chicago author-date (all authors)
- Scott, Charlotte, Sandrine Henri, and Martin Guilliams. 2014. “Mononuclear Phagocytes of the Intestine, the Skin, and the Lung.” IMMUNOLOGICAL REVIEWS 262 (1): 9–24. doi:10.1111/imr.12220.
- Vancouver
- 1.Scott C, Henri S, Guilliams M. Mononuclear phagocytes of the intestine, the skin, and the lung. IMMUNOLOGICAL REVIEWS. 2014;262(1):9–24.
- IEEE
- [1]C. Scott, S. Henri, and M. Guilliams, “Mononuclear phagocytes of the intestine, the skin, and the lung,” IMMUNOLOGICAL REVIEWS, vol. 262, no. 1, pp. 9–24, 2014.
@article{5839453,
abstract = {{Tissues that are in direct contact with the outside world face particular immunological challenges. The intestine, the skin, and the lung possess important mononuclear phagocyte populations to deal with these challenges, but the cellular origin of these phagocytes is strikingly different from one subset to another, with some cells derived from embryonic precursors and some from bone marrow-derived circulating monocytes. Here, we review the current knowledge regarding the developmental pathways that control the differentiation of mononuclear phagocytes in these barrier tissues. We have also attempted to build a theoretical model that could explain the distinct cellular origin of mononuclear phagocytes in these tissues.}},
author = {{Scott, Charlotte and Henri, Sandrine and Guilliams, Martin}},
issn = {{0105-2896}},
journal = {{IMMUNOLOGICAL REVIEWS}},
keywords = {{monocyte,macrophage,mononuclear phagocyte,dendritic cell,intestine,skin,lung,DENDRITIC CELL-DEVELOPMENT,RESIDENT ALVEOLAR MACROPHAGES,SINUSOIDAL ENDOTHELIAL-CELLS,PERIPHERAL LYMPHOID ORGANS,TRANSCRIPTION FACTOR E2-2,HEMATOPOIETIC STEM-CELLS,STIMULATING FACTOR-I,REGULATORY T-CELLS,LANGERHANS CELLS,LAMINA PROPRIA}},
language = {{eng}},
number = {{1}},
pages = {{9--24}},
title = {{Mononuclear phagocytes of the intestine, the skin, and the lung}},
url = {{http://dx.doi.org/10.1111/imr.12220}},
volume = {{262}},
year = {{2014}},
}
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