Microbiota and their role in the pathogenesis of oral mucositis
- Author
- Barbara Vanhoecke (UGent) , Tine De Ryck (UGent) , A Stringer, Tom Van de Wiele (UGent) and D Keefe
- Organization
- Abstract
- Oral mucositis in patients undergoing cancer therapy is a significant problem. Its prevalence ranges between 20 and 100%, depending on treatment type and protocols and patient-based variables. Mucositis is self-limiting when uncomplicated by infection. Unfortunately, the incidence of developing a local or systemic infection during the course of the treatment is very high. At this stage, it is unclear which role oral microbiota play in the onset, duration, and severity of oral mucositis. Nevertheless, there is growing interest in this underexplored topic, and new studies are being undertaken to unravel their impact on the pathogenesis of mucositis.
- Keywords
- mucositis, oral, microbiota, biofilm, radiotherapy, chemotherapy, PATIENTS RECEIVING RADIOTHERAPY, CHEMOTHERAPY-INDUCED MUCOSITIS, IRINOTECAN-INDUCED MUCOSITIS, GINGIVAL EPITHELIAL-CELLS, INTESTINAL MUCUS LAYER, NECK-CANCER PATIENTS, TOLL-LIKE RECEPTORS, GERM-FREE-MICE, DOUBLE-BLIND, SELECTIVE ELIMINATION
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-5839034
- MLA
- Vanhoecke, Barbara, et al. “Microbiota and Their Role in the Pathogenesis of Oral Mucositis.” ORAL DISEASES, vol. 21, no. 1, 2015, pp. 17–30, doi:10.1111/odi.12224.
- APA
- Vanhoecke, B., De Ryck, T., Stringer, A., Van de Wiele, T., & Keefe, D. (2015). Microbiota and their role in the pathogenesis of oral mucositis. ORAL DISEASES, 21(1), 17–30. https://doi.org/10.1111/odi.12224
- Chicago author-date
- Vanhoecke, Barbara, Tine De Ryck, A Stringer, Tom Van de Wiele, and D Keefe. 2015. “Microbiota and Their Role in the Pathogenesis of Oral Mucositis.” ORAL DISEASES 21 (1): 17–30. https://doi.org/10.1111/odi.12224.
- Chicago author-date (all authors)
- Vanhoecke, Barbara, Tine De Ryck, A Stringer, Tom Van de Wiele, and D Keefe. 2015. “Microbiota and Their Role in the Pathogenesis of Oral Mucositis.” ORAL DISEASES 21 (1): 17–30. doi:10.1111/odi.12224.
- Vancouver
- 1.Vanhoecke B, De Ryck T, Stringer A, Van de Wiele T, Keefe D. Microbiota and their role in the pathogenesis of oral mucositis. ORAL DISEASES. 2015;21(1):17–30.
- IEEE
- [1]B. Vanhoecke, T. De Ryck, A. Stringer, T. Van de Wiele, and D. Keefe, “Microbiota and their role in the pathogenesis of oral mucositis,” ORAL DISEASES, vol. 21, no. 1, pp. 17–30, 2015.
@article{5839034, abstract = {{Oral mucositis in patients undergoing cancer therapy is a significant problem. Its prevalence ranges between 20 and 100%, depending on treatment type and protocols and patient-based variables. Mucositis is self-limiting when uncomplicated by infection. Unfortunately, the incidence of developing a local or systemic infection during the course of the treatment is very high. At this stage, it is unclear which role oral microbiota play in the onset, duration, and severity of oral mucositis. Nevertheless, there is growing interest in this underexplored topic, and new studies are being undertaken to unravel their impact on the pathogenesis of mucositis.}}, author = {{Vanhoecke, Barbara and De Ryck, Tine and Stringer, A and Van de Wiele, Tom and Keefe, D}}, issn = {{1354-523X}}, journal = {{ORAL DISEASES}}, keywords = {{mucositis,oral,microbiota,biofilm,radiotherapy,chemotherapy,PATIENTS RECEIVING RADIOTHERAPY,CHEMOTHERAPY-INDUCED MUCOSITIS,IRINOTECAN-INDUCED MUCOSITIS,GINGIVAL EPITHELIAL-CELLS,INTESTINAL MUCUS LAYER,NECK-CANCER PATIENTS,TOLL-LIKE RECEPTORS,GERM-FREE-MICE,DOUBLE-BLIND,SELECTIVE ELIMINATION}}, language = {{eng}}, number = {{1}}, pages = {{17--30}}, title = {{Microbiota and their role in the pathogenesis of oral mucositis}}, url = {{http://doi.org/10.1111/odi.12224}}, volume = {{21}}, year = {{2015}}, }
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