Treatment of patellofemoral cartilage defects in the knee by autologous matrix-induced chondrogenesis (AMIC)
- Author
- Aad Dhollander, Kris Moens, JAAP VAN DER MAAS (UGent) , Peter Verdonk (UGent) , Karl Almqvist (UGent) and Jan Victor (UGent)
- Organization
- Abstract
- This study presents the prospective two-year clinical and MRI outcome of autologous matrix-induced chondrogenesis (AMIC) for the treatment of patellofemoral cartilage defects in the knee. Ten patients were clinically prospectively evaluated during 2 years. MRI data were analysed based on the original and modified MOCART (Magnetic Resonance Observation of Cartilage Repair Tissue) scoring system. A satisfying clinical improvement became apparent during the 24 months of follow-up. The MOCART scoring system revealed a slight tendency to deterioration on MIRE between one and 2 years of follow-up. However, the difference was not statistical significant. All cases showed subchondral lamina changes. The formation of intralesional osteophytes was observed in 3 of the 10 patients (30%). In conclusion, AMIC is safe and feasible for the treatment of symptomatic patellofemoral cartilage defects and resulted in a clinical improvement. However, the favourable clinical outcome of the AMIC technique was not confirmed by the MIRE findings.
- Keywords
- VISUAL ANALOG SCALE, OUTCOME SCORE KOOS, FEMORAL JOINT MECHANICS, THICKNESS CHONDRAL DEFECTS, CHONDROCYTE IMPLANTATION, REPAIR TISSUE, FOLLOW-UP, MICROFRACTURE, ARTHROSCOPIES, TRANSPLANTATION
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-5837727
- MLA
- Dhollander, Aad, Kris Moens, JAAP VAN DER MAAS, et al. “Treatment of Patellofemoral Cartilage Defects in the Knee by Autologous Matrix-induced Chondrogenesis (AMIC).” ACTA ORTHOPAEDICA BELGICA 80.2 (2014): 251–259. Print.
- APA
- Dhollander, A., Moens, K., VAN DER MAAS, J., Verdonk, P., Almqvist, K., & Victor, J. (2014). Treatment of patellofemoral cartilage defects in the knee by autologous matrix-induced chondrogenesis (AMIC). ACTA ORTHOPAEDICA BELGICA, 80(2), 251–259.
- Chicago author-date
- Dhollander, Aad, Kris Moens, JAAP VAN DER MAAS, Peter Verdonk, Karl Almqvist, and Jan Victor. 2014. “Treatment of Patellofemoral Cartilage Defects in the Knee by Autologous Matrix-induced Chondrogenesis (AMIC).” Acta Orthopaedica Belgica 80 (2): 251–259.
- Chicago author-date (all authors)
- Dhollander, Aad, Kris Moens, JAAP VAN DER MAAS, Peter Verdonk, Karl Almqvist, and Jan Victor. 2014. “Treatment of Patellofemoral Cartilage Defects in the Knee by Autologous Matrix-induced Chondrogenesis (AMIC).” Acta Orthopaedica Belgica 80 (2): 251–259.
- Vancouver
- 1.Dhollander A, Moens K, VAN DER MAAS J, Verdonk P, Almqvist K, Victor J. Treatment of patellofemoral cartilage defects in the knee by autologous matrix-induced chondrogenesis (AMIC). ACTA ORTHOPAEDICA BELGICA. 2014;80(2):251–9.
- IEEE
- [1]A. Dhollander, K. Moens, J. VAN DER MAAS, P. Verdonk, K. Almqvist, and J. Victor, “Treatment of patellofemoral cartilage defects in the knee by autologous matrix-induced chondrogenesis (AMIC),” ACTA ORTHOPAEDICA BELGICA, vol. 80, no. 2, pp. 251–259, 2014.
@article{5837727,
abstract = {This study presents the prospective two-year clinical and MRI outcome of autologous matrix-induced chondrogenesis (AMIC) for the treatment of patellofemoral cartilage defects in the knee. Ten patients were clinically prospectively evaluated during 2 years. MRI data were analysed based on the original and modified MOCART (Magnetic Resonance Observation of Cartilage Repair Tissue) scoring system. A satisfying clinical improvement became apparent during the 24 months of follow-up. The MOCART scoring system revealed a slight tendency to deterioration on MIRE between one and 2 years of follow-up. However, the difference was not statistical significant. All cases showed subchondral lamina changes. The formation of intralesional osteophytes was observed in 3 of the 10 patients (30%). In conclusion, AMIC is safe and feasible for the treatment of symptomatic patellofemoral cartilage defects and resulted in a clinical improvement. However, the favourable clinical outcome of the AMIC technique was not confirmed by the MIRE findings.},
author = {Dhollander, Aad and Moens, Kris and VAN DER MAAS, JAAP and Verdonk, Peter and Almqvist, Karl and Victor, Jan},
issn = {0001-6462},
journal = {ACTA ORTHOPAEDICA BELGICA},
keywords = {VISUAL ANALOG SCALE,OUTCOME SCORE KOOS,FEMORAL JOINT MECHANICS,THICKNESS CHONDRAL DEFECTS,CHONDROCYTE IMPLANTATION,REPAIR TISSUE,FOLLOW-UP,MICROFRACTURE,ARTHROSCOPIES,TRANSPLANTATION},
language = {eng},
number = {2},
pages = {251--259},
title = {Treatment of patellofemoral cartilage defects in the knee by autologous matrix-induced chondrogenesis (AMIC)},
volume = {80},
year = {2014},
}