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Room temperature Q-band electron magnetic resonance study of radicals in X-ray-irradiated L-threonine single crystals

Gauthier Vanhaelewyn (UGent) , Henk Vrielinck (UGent) and Freddy Callens (UGent)
(2014) RADIATION PROTECTION DOSIMETRY. 159(1-4). p.155-163
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Abstract
In the past, decennia radiation-induced radicals were successfully identified by electron magnetic resonance (EMR) in several solid-state amino acids and sugars. The authors present a room temperature (RT) EMR study of the stable radicals produced by X-ray-irradiation in the amino acid l-threonine (CH3CH(OH)CH(NH3+)COO-). Its chemical structure is similar to that of the well-known dosimetric material l-alanine (CH3CH(NH3+)COO-), and radiation defects in l-threonine may straightforwardly be compared with the extensively studied l-alanine radicals. The hyperfine coupling tensors of three different radicals were determined at RT using electron nuclear double resonance. These results indicate that the two most abundant radicals share the same basic structure (CH3C)-C-aEuro cent(OH)CH(NH3+)COO-, obtained by H-abstraction, but are stabilised in slightly different conformations. The third radical is most probably obtained by deamination (CH3CH(OH)(CHCOO-)-C-aEuro cent), similar in structure to the stable alanine radical.
Keywords
ALANINE, DFT, ENDOR, EPR, RADIATION-INDUCED RADICALS, 77 K, SIMULATION, DNA

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Chicago
Vanhaelewyn, Gauthier, Henk Vrielinck, and Freddy Callens. 2014. “Room Temperature Q-band Electron Magnetic Resonance Study of Radicals in X-ray-irradiated L-threonine Single Crystals.” Radiation Protection Dosimetry 159 (1-4): 155–163.
APA
Vanhaelewyn, G., Vrielinck, H., & Callens, F. (2014). Room temperature Q-band electron magnetic resonance study of radicals in X-ray-irradiated L-threonine single crystals. RADIATION PROTECTION DOSIMETRY, 159(1-4), 155–163.
Vancouver
1.
Vanhaelewyn G, Vrielinck H, Callens F. Room temperature Q-band electron magnetic resonance study of radicals in X-ray-irradiated L-threonine single crystals. RADIATION PROTECTION DOSIMETRY. 2014;159(1-4):155–63.
MLA
Vanhaelewyn, Gauthier, Henk Vrielinck, and Freddy Callens. “Room Temperature Q-band Electron Magnetic Resonance Study of Radicals in X-ray-irradiated L-threonine Single Crystals.” RADIATION PROTECTION DOSIMETRY 159.1-4 (2014): 155–163. Print.
@article{5836457,
  abstract     = {In the past, decennia radiation-induced radicals were successfully identified by electron magnetic resonance (EMR) in several solid-state amino acids and sugars. The authors present a room temperature (RT) EMR study of the stable radicals produced by X-ray-irradiation in the amino acid l-threonine (CH3CH(OH)CH(NH3+)COO-). Its chemical structure is similar to that of the well-known dosimetric material l-alanine (CH3CH(NH3+)COO-), and radiation defects in l-threonine may straightforwardly be compared with the extensively studied l-alanine radicals. The hyperfine coupling tensors of three different radicals were determined at RT using electron nuclear double resonance. These results indicate that the two most abundant radicals share the same basic structure (CH3C)-C-aEuro cent(OH)CH(NH3+)COO-, obtained by H-abstraction, but are stabilised in slightly different conformations. The third radical is most probably obtained by deamination (CH3CH(OH)(CHCOO-)-C-aEuro cent), similar in structure to the stable alanine radical.},
  author       = {Vanhaelewyn, Gauthier and Vrielinck, Henk and Callens, Freddy},
  issn         = {0144-8420},
  journal      = {RADIATION PROTECTION DOSIMETRY},
  keyword      = {ALANINE,DFT,ENDOR,EPR,RADIATION-INDUCED RADICALS,77 K,SIMULATION,DNA},
  language     = {eng},
  number       = {1-4},
  pages        = {155--163},
  title        = {Room temperature Q-band electron magnetic resonance study of radicals in X-ray-irradiated L-threonine single crystals},
  url          = {http://dx.doi.org/10.1093/rpd/ncu123},
  volume       = {159},
  year         = {2014},
}

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