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A probiotic fermented milk drink containing Lactobacillus casei strain Shirota improves stool consistency of subjects with hard stools

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Abstract
The aim of this study was to investigate the effect of a fermented milk drink containing Lactobacillus casei Shirota (LcS) on the bowel habit (with emphasis on stool consistency) of subjects suffering from hard stools. Secondly, it was tested whether the probiotic strain (LcS), was able to survive throughout the gastrointestinal tract. A double-blind, placebo-controlled, randomized study was carried out over an eight-week period in subjects with symptoms o f constipation (n=120). To all subjects, 65 ml/day of a probiotic fermented milk drink containing LcS or a placebo was administered. Patients completed a questionnaire to assess the consistency of their stools. In half of the study population, the survival of the probiotic strain (LcS) was tested using (i) culture and (ii) an LcS specific monoclonal antibody to identify the cultured colonies as LcS (ELISA). There was a significant decrease in stool hardening when consuming a fermented milk drink containing LcS. The observed clinical effect went hand in hand with the observed microbiological effect as the number of viable LcS bacteria in the faeces increased when consuming fermented milk drink containing LcS and decreased during wash-out.

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MLA
Tilley, Linde, Katleen Keppens, Akira Kushiro, et al. “A Probiotic Fermented Milk Drink Containing Lactobacillus Casei Strain Shirota Improves Stool Consistency of Subjects with Hard Stools.” INTERNATIONAL JOURNAL OF PROBIOTICS AND PREBIOTICS 9.1-2 (2014): 23–29. Print.
APA
Tilley, L., Keppens, K., Kushiro, A., Takada, T., Sakai, T., Vaneechoutte, M., & Degeest, B. (2014). A probiotic fermented milk drink containing Lactobacillus casei strain Shirota improves stool consistency of subjects with hard stools. INTERNATIONAL JOURNAL OF PROBIOTICS AND PREBIOTICS, 9(1-2), 23–29.
Chicago author-date
Tilley, Linde, Katleen Keppens, Akira Kushiro, Toshihiko Takada, Takafumi Sakai, Mario Vaneechoutte, and Bart Degeest. 2014. “A Probiotic Fermented Milk Drink Containing Lactobacillus Casei Strain Shirota Improves Stool Consistency of Subjects with Hard Stools.” International Journal of Probiotics and Prebiotics 9 (1-2): 23–29.
Chicago author-date (all authors)
Tilley, Linde, Katleen Keppens, Akira Kushiro, Toshihiko Takada, Takafumi Sakai, Mario Vaneechoutte, and Bart Degeest. 2014. “A Probiotic Fermented Milk Drink Containing Lactobacillus Casei Strain Shirota Improves Stool Consistency of Subjects with Hard Stools.” International Journal of Probiotics and Prebiotics 9 (1-2): 23–29.
Vancouver
1.
Tilley L, Keppens K, Kushiro A, Takada T, Sakai T, Vaneechoutte M, et al. A probiotic fermented milk drink containing Lactobacillus casei strain Shirota improves stool consistency of subjects with hard stools. INTERNATIONAL JOURNAL OF PROBIOTICS AND PREBIOTICS. 2014;9(1-2):23–9.
IEEE
[1]
L. Tilley et al., “A probiotic fermented milk drink containing Lactobacillus casei strain Shirota improves stool consistency of subjects with hard stools,” INTERNATIONAL JOURNAL OF PROBIOTICS AND PREBIOTICS, vol. 9, no. 1–2, pp. 23–29, 2014.
@article{5828206,
  abstract     = {The aim of this study was to investigate the effect of a fermented milk drink containing Lactobacillus casei Shirota (LcS) on the bowel habit (with emphasis on stool consistency) of subjects suffering from hard stools. Secondly, it was tested whether the probiotic strain (LcS), was able to survive throughout the gastrointestinal tract. A double-blind, placebo-controlled, randomized study was carried out over an eight-week period in subjects with symptoms o f constipation (n=120). To all subjects, 65 ml/day of a probiotic fermented milk drink containing LcS or a placebo was administered. Patients completed a questionnaire to assess the consistency of their stools. In half of the study population, the survival of the probiotic strain (LcS) was tested using (i) culture and (ii) an LcS specific monoclonal antibody to identify the cultured colonies as LcS (ELISA). There was a significant decrease in stool hardening when consuming a fermented milk drink containing LcS. The observed clinical effect went hand in hand with the observed microbiological effect as the number of viable LcS bacteria in the faeces increased when consuming fermented milk drink containing LcS and decreased during wash-out.},
  author       = {Tilley, Linde and Keppens, Katleen and Kushiro, Akira and Takada, Toshihiko and Sakai, Takafumi and Vaneechoutte, Mario and Degeest, Bart},
  issn         = {1555-1431},
  journal      = {INTERNATIONAL JOURNAL OF PROBIOTICS AND PREBIOTICS},
  language     = {eng},
  number       = {1-2},
  pages        = {23--29},
  title        = {A probiotic fermented milk drink containing Lactobacillus casei strain Shirota improves stool consistency of subjects with hard stools},
  volume       = {9},
  year         = {2014},
}