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An insight on bacterial cellular targets of photodynamic inactivation

(2014) FUTURE MEDICINAL CHEMISTRY. 6(2). p.141-164
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Abstract
The emergence of microbial resistance is becoming a global problem in clinical and environmental areas. As such, the development of drugs with novel modes of action will be vital to meet the threats created by the rise in microbial resistance. Microbial photodynamic inactivation is receiving considerable attention for its potentialities as a new antimicrobial treatment. This review addresses the interactions between photosensitizers and bacterial cells (binding site and cellular localization), the ultrastructural, morphological and functional changes observed at initial stages and during the course of photodynamic inactivation, the oxidative alterations in specific molecular targets, and a possible development of resistance.
Keywords
SINGLET OXYGEN, PSEUDOMONAS-AERUGINOSA, METHYLENE-BLUE, PROPIONIBACTERIUM-ACNES, TOLUIDINE BLUE O, 5-AMINOLEVULINIC ACID, ESCHERICHIA-COLI-B, STAPHYLOCOCCUS-EPIDERMIDIS BIOFILMS, GRAM-NEGATIVE BACTERIA, DELTA-AMINOLEVULINIC-ACID

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Citation

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MLA
Alves, Eliana, Maria AF Faustino, Maria GPMS Neves, et al. “An Insight on Bacterial Cellular Targets of Photodynamic Inactivation.” FUTURE MEDICINAL CHEMISTRY 6.2 (2014): 141–164. Print.
APA
Alves, E., Faustino, M. A., Neves, M. G., Cunha, A., Tomé, J., & Almeida, A. (2014). An insight on bacterial cellular targets of photodynamic inactivation. FUTURE MEDICINAL CHEMISTRY, 6(2), 141–164.
Chicago author-date
Alves, Eliana, Maria AF Faustino, Maria GPMS Neves, Angela Cunha, João Tomé, and Adelaide Almeida. 2014. “An Insight on Bacterial Cellular Targets of Photodynamic Inactivation.” Future Medicinal Chemistry 6 (2): 141–164.
Chicago author-date (all authors)
Alves, Eliana, Maria AF Faustino, Maria GPMS Neves, Angela Cunha, João Tomé, and Adelaide Almeida. 2014. “An Insight on Bacterial Cellular Targets of Photodynamic Inactivation.” Future Medicinal Chemistry 6 (2): 141–164.
Vancouver
1.
Alves E, Faustino MA, Neves MG, Cunha A, Tomé J, Almeida A. An insight on bacterial cellular targets of photodynamic inactivation. FUTURE MEDICINAL CHEMISTRY. 2014;6(2):141–64.
IEEE
[1]
E. Alves, M. A. Faustino, M. G. Neves, A. Cunha, J. Tomé, and A. Almeida, “An insight on bacterial cellular targets of photodynamic inactivation,” FUTURE MEDICINAL CHEMISTRY, vol. 6, no. 2, pp. 141–164, 2014.
@article{5768586,
  abstract     = {The emergence of microbial resistance is becoming a global problem in clinical and environmental areas. As such, the development of drugs with novel modes of action will be vital to meet the threats created by the rise in microbial resistance. Microbial photodynamic inactivation is receiving considerable attention for its potentialities as a new antimicrobial treatment. This review addresses the interactions between photosensitizers and bacterial cells (binding site and cellular localization), the ultrastructural, morphological and functional changes observed at initial stages and during the course of photodynamic inactivation, the oxidative alterations in specific molecular targets, and a possible development of resistance.},
  author       = {Alves, Eliana and Faustino, Maria AF and Neves, Maria GPMS and Cunha, Angela and Tomé, João and Almeida, Adelaide},
  issn         = {1756-8919},
  journal      = {FUTURE MEDICINAL CHEMISTRY},
  keywords     = {SINGLET OXYGEN,PSEUDOMONAS-AERUGINOSA,METHYLENE-BLUE,PROPIONIBACTERIUM-ACNES,TOLUIDINE BLUE O,5-AMINOLEVULINIC ACID,ESCHERICHIA-COLI-B,STAPHYLOCOCCUS-EPIDERMIDIS BIOFILMS,GRAM-NEGATIVE BACTERIA,DELTA-AMINOLEVULINIC-ACID},
  language     = {eng},
  number       = {2},
  pages        = {141--164},
  title        = {An insight on bacterial cellular targets of photodynamic inactivation},
  url          = {http://dx.doi.org/10.4155/fmc.13.211},
  volume       = {6},
  year         = {2014},
}

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