Ghent University Academic Bibliography

Advanced

Effect, persistence, and virulence of coagulase-negative Staphylococcus species associated with ruminant udder health

Wannes Vanderhaeghen, Sofie Piepers UGent, F Leroy, E Van Coillie, Freddy Haesebrouck UGent and Sarne De Vliegher UGent (2014) JOURNAL OF DAIRY SCIENCE. 97(9). p.5275-5293
abstract
The aim of this review is to assess the effect of coagulase-negative staphylococci (CNS) species on udder health and milk yield in ruminants, and to evaluate the capacity of CNS to cause persistent intramammary infections (IMI). Furthermore, the literature on factors suspected of playing a role in the pathogenicity of IMI-associated CNS, such as biofilm formation and the presence of various putative virulence genes, is discussed. The focus is on the 5 CNS species that have been most frequently identified as causing bovine IMI using reliable molecular identification methods (Staphylococcus chromogenes, Staphylococcus simulans, Staphylococcus haemolyticus, Staphylococcus xylosus, and Staphylococcus epidermidis). Although the effect on somatic cell count and milk production is accepted to be generally limited or nonexistent for CNS as a group, indications are that the typical effects differ between CNS species and perhaps even strains. It has also become clear that many CNS species can cause persistent IMI, contrary to what has long been believed. However, this trait appears to be quite complicated, being partly strain dependent and partly dependent on the host's immunity. Consistent definitions of persistence and more uniform methods for testing this phenomenon will benefit future research. The factors explaining the anticipated differences in pathogenic behavior appear to be more difficult to evaluate. Biofilm formation and the presence of various staphylococcal virulence factors do not seem to (directly) influence the effect of CNS on IMI but the available information is indirect or insufficient to draw consistent conclusions. Future studies on the effect, persistence, and virulence of the different CNS species associated with IMI would benefit from using larger and perhaps even shared strain collections and from adjusting study designs to a common framework, as the large variation currently existing therein is a major problem. Also within-species variation should be investigated.
Please use this url to cite or link to this publication:
author
organization
alternative title
Invited review: Effect, persistence, and virulence of coagulase-negative Staphylococcus species associated with ruminant udder health
year
type
journalArticle (review)
publication status
published
subject
keyword
DIAGNOSING INTRAMAMMARY INFECTIONS, CLINICAL MASTITIS, MAJOR MASTITIS PATHOGENS, SOMATIC-CELL COUNT, intramammary infection, effect, persistence, biofilm, virulence, MAMMARY EPITHELIAL-CELLS, SUBCLINICAL BOVINE MASTITIS, coagulase-negative staphylococci (CNS), BIOFILM FORMATION, MILK-YIELD, DAIRY HEIFERS, INTENSIVE-CARE-UNIT
journal title
JOURNAL OF DAIRY SCIENCE
J. Dairy Sci.
volume
97
issue
9
pages
5275 - 5293
Web of Science type
Review
Web of Science id
000340580400001
JCR category
AGRICULTURE, DAIRY & ANIMAL SCIENCE
JCR impact factor
2.573 (2014)
JCR rank
2/57 (2014)
JCR quartile
1 (2014)
ISSN
0022-0302
DOI
10.3168/jds.2013-7775
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
5723958
handle
http://hdl.handle.net/1854/LU-5723958
date created
2014-10-16 13:04:53
date last changed
2016-12-19 15:40:58
@article{5723958,
  abstract     = {The aim of this review is to assess the effect of coagulase-negative staphylococci (CNS) species on udder health and milk yield in ruminants, and to evaluate the capacity of CNS to cause persistent intramammary infections (IMI). Furthermore, the literature on factors suspected of playing a role in the pathogenicity of IMI-associated CNS, such as biofilm formation and the presence of various putative virulence genes, is discussed. The focus is on the 5 CNS species that have been most frequently identified as causing bovine IMI using reliable molecular identification methods (Staphylococcus chromogenes, Staphylococcus simulans, Staphylococcus haemolyticus, Staphylococcus xylosus, and Staphylococcus epidermidis). Although the effect on somatic cell count and milk production is accepted to be generally limited or nonexistent for CNS as a group, indications are that the typical effects differ between CNS species and perhaps even strains. It has also become clear that many CNS species can cause persistent IMI, contrary to what has long been believed. However, this trait appears to be quite complicated, being partly strain dependent and partly dependent on the host's immunity. Consistent definitions of persistence and more uniform methods for testing this phenomenon will benefit future research. The factors explaining the anticipated differences in pathogenic behavior appear to be more difficult to evaluate. Biofilm formation and the presence of various staphylococcal virulence factors do not seem to (directly) influence the effect of CNS on IMI but the available information is indirect or insufficient to draw consistent conclusions. Future studies on the effect, persistence, and virulence of the different CNS species associated with IMI would benefit from using larger and perhaps even shared strain collections and from adjusting study designs to a common framework, as the large variation currently existing therein is a major problem. Also within-species variation should be investigated.},
  author       = {Vanderhaeghen, Wannes and Piepers, Sofie and Leroy, F and Van Coillie, E and Haesebrouck, Freddy and De Vliegher, Sarne},
  issn         = {0022-0302},
  journal      = {JOURNAL OF DAIRY SCIENCE},
  keyword      = {DIAGNOSING INTRAMAMMARY INFECTIONS,CLINICAL MASTITIS,MAJOR MASTITIS PATHOGENS,SOMATIC-CELL COUNT,intramammary infection,effect,persistence,biofilm,virulence,MAMMARY EPITHELIAL-CELLS,SUBCLINICAL BOVINE MASTITIS,coagulase-negative staphylococci (CNS),BIOFILM FORMATION,MILK-YIELD,DAIRY HEIFERS,INTENSIVE-CARE-UNIT},
  language     = {eng},
  number       = {9},
  pages        = {5275--5293},
  title        = {Effect, persistence, and virulence of coagulase-negative Staphylococcus species associated with ruminant udder health},
  url          = {http://dx.doi.org/10.3168/jds.2013-7775},
  volume       = {97},
  year         = {2014},
}

Chicago
Vanderhaeghen, Wannes, Sofie Piepers, F Leroy, E Van Coillie, Freddy Haesebrouck, and Sarne De Vliegher. 2014. “Effect, Persistence, and Virulence of Coagulase-negative Staphylococcus Species Associated with Ruminant Udder Health.” Journal of Dairy Science 97 (9): 5275–5293.
APA
Vanderhaeghen, W., Piepers, S., Leroy, F., Van Coillie, E., Haesebrouck, F., & De Vliegher, S. (2014). Effect, persistence, and virulence of coagulase-negative Staphylococcus species associated with ruminant udder health. JOURNAL OF DAIRY SCIENCE, 97(9), 5275–5293.
Vancouver
1.
Vanderhaeghen W, Piepers S, Leroy F, Van Coillie E, Haesebrouck F, De Vliegher S. Effect, persistence, and virulence of coagulase-negative Staphylococcus species associated with ruminant udder health. JOURNAL OF DAIRY SCIENCE. 2014;97(9):5275–93.
MLA
Vanderhaeghen, Wannes, Sofie Piepers, F Leroy, et al. “Effect, Persistence, and Virulence of Coagulase-negative Staphylococcus Species Associated with Ruminant Udder Health.” JOURNAL OF DAIRY SCIENCE 97.9 (2014): 5275–5293. Print.