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Poly(ADP-ribose)polymerase activity controls plant growth by promoting leaf cell number

Philipp Schulz, Karel Jansseune, Thomas Degenkolbe, Michaël Méret, Hannes Claeys, Aleksandra Skirycz UGent, Markus Teige, Lothar Willmitzer and Matthew A Hannah (2014) PLOS ONE. 9(2).
abstract
A changing global environment, rising population and increasing demand for biofuels are challenging agriculture and creating a need for technologies to increase biomass production. Here we demonstrate that the inhibition of poly (ADPribose) polymerase activity is a promising technology to achieve this under non-stress conditions. Furthermore, we investigate the basis of this growth enhancement via leaf series and kinematic cell analysis as well as single leaf transcriptomics and plant metabolomics under non-stress conditions. These data indicate a regulatory function of PARP within cell growth and potentially development. PARP inhibition enhances growth of Arabidopsis thaliana by enhancing the cell number. Time course single leaf transcriptomics shows that PARP inhibition regulates a small subset of genes which are related to growth promotion, cell cycle and the control of metabolism. This is supported by metabolite analysis showing overall changes in primary and particularly secondary metabolism. Taken together the results indicate a versatile function of PARP beyond its previously reported roles in controlling plant stress tolerance and thus can be a useful target for enhancing biomass production.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
ARABIDOPSIS-THALIANA, DARK-INDUCIBLE GENES, ADP-RIBOSYLATION, OXIDATIVE STRESS, OSMOTIC-STRESS, POLYMERASE, PROTEINS, POLY(ADP-RIBOSYL)ATION, RESPONSES, EXPRESSION
journal title
PLOS ONE
PLoS One
volume
9
issue
2
article number
e90322
pages
15 pages
Web of Science type
Article
Web of Science id
000332396200169
JCR category
MULTIDISCIPLINARY SCIENCES
JCR impact factor
3.234 (2014)
JCR rank
9/57 (2014)
JCR quartile
1 (2014)
ISSN
1932-6203
DOI
10.1371/journal.pone.0090322
language
English
UGent publication?
yes
classification
A1
copyright statement
I have retained and own the full copyright for this publication
id
5723108
handle
http://hdl.handle.net/1854/LU-5723108
date created
2014-10-15 14:38:13
date last changed
2016-12-21 15:41:29
@article{5723108,
  abstract     = {A changing global environment, rising population and increasing demand for biofuels are challenging agriculture and creating a need for technologies to increase biomass production. Here we demonstrate that the inhibition of poly (ADPribose) polymerase activity is a promising technology to achieve this under non-stress conditions. Furthermore, we investigate the basis of this growth enhancement via leaf series and kinematic cell analysis as well as single leaf transcriptomics and plant metabolomics under non-stress conditions. These data indicate a regulatory function of PARP within cell growth and potentially development. PARP inhibition enhances growth of Arabidopsis thaliana by enhancing the cell number. Time course single leaf transcriptomics shows that PARP inhibition regulates a small subset of genes which are related to growth promotion, cell cycle and the control of metabolism. This is supported by metabolite analysis showing overall changes in primary and particularly secondary metabolism. Taken together the results indicate a versatile function of PARP beyond its previously reported roles in controlling plant stress tolerance and thus can be a useful target for enhancing biomass production.},
  articleno    = {e90322},
  author       = {Schulz, Philipp and Jansseune, Karel and Degenkolbe, Thomas and M{\'e}ret, Micha{\"e}l and Claeys, Hannes and Skirycz, Aleksandra and Teige, Markus and Willmitzer, Lothar and Hannah, Matthew A},
  issn         = {1932-6203},
  journal      = {PLOS ONE},
  keyword      = {ARABIDOPSIS-THALIANA,DARK-INDUCIBLE GENES,ADP-RIBOSYLATION,OXIDATIVE STRESS,OSMOTIC-STRESS,POLYMERASE,PROTEINS,POLY(ADP-RIBOSYL)ATION,RESPONSES,EXPRESSION},
  language     = {eng},
  number       = {2},
  pages        = {15},
  title        = {Poly(ADP-ribose)polymerase activity controls plant growth by promoting leaf cell number},
  url          = {http://dx.doi.org/10.1371/journal.pone.0090322},
  volume       = {9},
  year         = {2014},
}

Chicago
Schulz, Philipp, Karel Jansseune, Thomas Degenkolbe, Michaël Méret, Hannes Claeys, Aleksandra Skirycz, Markus Teige, Lothar Willmitzer, and Matthew A Hannah. 2014. “Poly(ADP-ribose)polymerase Activity Controls Plant Growth by Promoting Leaf Cell Number.” Plos One 9 (2).
APA
Schulz, P., Jansseune, K., Degenkolbe, T., Méret, M., Claeys, H., Skirycz, A., Teige, M., et al. (2014). Poly(ADP-ribose)polymerase activity controls plant growth by promoting leaf cell number. PLOS ONE, 9(2).
Vancouver
1.
Schulz P, Jansseune K, Degenkolbe T, Méret M, Claeys H, Skirycz A, et al. Poly(ADP-ribose)polymerase activity controls plant growth by promoting leaf cell number. PLOS ONE. 2014;9(2).
MLA
Schulz, Philipp, Karel Jansseune, Thomas Degenkolbe, et al. “Poly(ADP-ribose)polymerase Activity Controls Plant Growth by Promoting Leaf Cell Number.” PLOS ONE 9.2 (2014): n. pag. Print.