Advanced search
1 file | 2.72 MB

Adding serum estradiol measurements to ultrasound monitoring does not change the yield of mature oocytes in IVF/ICSI

Frank Vandekerckhove (UGent) , Jan Gerris (UGent) , Stijn Vansteelandt (UGent) and Petra De Sutter (UGent)
(2014) GYNECOLOGICAL ENDOCRINOLOGY. 30(9). p.649-652
Author
Organization
Abstract
In a non-randomized, comparative prospective study (416 patients) we compared the outcome of IVF/ICSI in two parallel control groups: one in which patients were followed up using combined monitoring (ultrasound plus serum estradiol monitoring, the UHM group) and one in which only ultrasound monitoring was used (the UM group). This study has taken the number of mature oocytes at the moment of egg retrieval as its primary end variable. After adjustment for age, gravidity, antagonist protocol, AMH and infertility diagnosis, the average difference in number of mature oocytes between the UHM group and the UM group was -0.4 (95% CI: -1.7 to 1.0), which met our definition of clinical equivalence (95% CI for the adjusted mean difference between -2 and 2). Larger studies are still needed to evaluate the differences in the live birth rates per cycle and to further confirm that blood sampling definitively has no added value in monitoring ovarian stimulation for IVF/ICSI.
Keywords
SOET, INVITRO, CYCLES, GONADOTROPIN, STIMULATION, EMBRYO TRANSFER, IN-VITRO FERTILIZATION, ultrasound, monitoring, mature oocyte, IVF, HORMONE, Estradiol

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 2.72 MB

Citation

Please use this url to cite or link to this publication:

Chicago
Vandekerckhove, Frank, Jan Gerris, Stijn Vansteelandt, and Petra De Sutter. 2014. “Adding Serum Estradiol Measurements to Ultrasound Monitoring Does Not Change the Yield of Mature Oocytes in IVF/ICSI.” Gynecological Endocrinology 30 (9): 649–652.
APA
Vandekerckhove, F., Gerris, J., Vansteelandt, S., & De Sutter, P. (2014). Adding serum estradiol measurements to ultrasound monitoring does not change the yield of mature oocytes in IVF/ICSI. GYNECOLOGICAL ENDOCRINOLOGY, 30(9), 649–652.
Vancouver
1.
Vandekerckhove F, Gerris J, Vansteelandt S, De Sutter P. Adding serum estradiol measurements to ultrasound monitoring does not change the yield of mature oocytes in IVF/ICSI. GYNECOLOGICAL ENDOCRINOLOGY. 2014;30(9):649–52.
MLA
Vandekerckhove, Frank, Jan Gerris, Stijn Vansteelandt, et al. “Adding Serum Estradiol Measurements to Ultrasound Monitoring Does Not Change the Yield of Mature Oocytes in IVF/ICSI.” GYNECOLOGICAL ENDOCRINOLOGY 30.9 (2014): 649–652. Print.
@article{5720179,
  abstract     = {In a non-randomized, comparative prospective study (416 patients) we compared the outcome of IVF/ICSI in two parallel control groups: one in which patients were followed up using combined monitoring (ultrasound plus serum estradiol monitoring, the UHM group) and one in which only ultrasound monitoring was used (the UM group). This study has taken the number of mature oocytes at the moment of egg retrieval as its primary end variable. After adjustment for age, gravidity, antagonist protocol, AMH and infertility diagnosis, the average difference in number of mature oocytes between the UHM group and the UM group was -0.4 (95\% CI: -1.7 to 1.0), which met our definition of clinical equivalence (95\% CI for the adjusted mean difference between -2 and 2). Larger studies are still needed to evaluate the differences in the live birth rates per cycle and to further confirm that blood sampling definitively has no added value in monitoring ovarian stimulation for IVF/ICSI.},
  author       = {Vandekerckhove, Frank and Gerris, Jan and Vansteelandt, Stijn and De Sutter, Petra},
  issn         = {0951-3590},
  journal      = {GYNECOLOGICAL ENDOCRINOLOGY},
  language     = {eng},
  number       = {9},
  pages        = {649--652},
  title        = {Adding serum estradiol measurements to ultrasound monitoring does not change the yield of mature oocytes in IVF/ICSI},
  url          = {http://dx.doi.org/10.3109/09513590.2014.912267},
  volume       = {30},
  year         = {2014},
}

Altmetric
View in Altmetric
Web of Science
Times cited: