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Bioavailability and toxicity of nickel to freshwater organisms: a modeling approach

Nele Deleebeeck (2008)
abstract
Water quality criteria setting for metals is hampered by the fact that the bioavailability and hence also the toxicity of many metals is largely influenced by physicochemical parameters such as water hardness, pH and dissolved organic matter. Consequently, a single water quality criterium may be too conservative for certain water bodies whereas it may not be protective enough for other water bodies. This metal-specific issue can be overcome with the development of mathematical models capable of predicting metal bioavailability and toxicity as a function of water chemistry. In the first part of this doctoral thesis it was investigated to what extent several physicochemical parameters (such as calcium, magnesium, pH, dissolved organic matter) affect the acute and chronic toxicity of nickel to freshwater organisms. For each testing organism (a unicellular green alga, an aquatic invertebrate and a fish) a bioavailability model was developed capable of accurately predicting nickel toxicity in both artificial and natural waters. An important point of concern was that bioavailability models such as those developed in the first part of this doctoral thesis may underestimate metal toxicity in waters with hardness far below the lower water hardness boundary for which these models were originally developed and validated using ‘standard’ test organisms. In the second part of this research it was therefore investigated whether this concern is scientifically justified for nickel. A series of toxicity tests with field-organisms (microalgae and water fleas) originating from soft and hard surface waters demonstrated that in most cases soft water organisms are equally sensitive to nickel as hard water organisms and that a single bioavailability model can be used to predict the water hardness-dependent toxicity of nickel to soft and hard water organisms. The data and models generated in this thesis were already used in the European risk assessment of nickel and nickel compounds. The pan-European water quality criterium for nickel will be based on the outcome of this risk assessment. Current developments at the international regulatory level feed the expectation that the application domain of this thesis will further expand.
Please use this url to cite or link to this publication:
author
promoter
UGent and UGent
organization
alternative title
Biobeschikbaarheid en toxiciteit van nikkel voor zoetwaterorganismen: een modelmatige bendadering
year
type
dissertation (monograph)
subject
pages
X, 294 pages
publisher
Ghent University
place of publication
Gent
defense location
Gent, zaal Jozef Plateau
defense date
2008-03-20 16:00
ISBN
978-90-5989-233-0
language
English
UGent publication?
yes
classification
D1
copyright statement
I have retained and own the full copyright for this publication
id
530349
handle
http://hdl.handle.net/1854/LU-530349
alternative location
http://lib.ugent.be/fulltxt/RUG01/001/275/994/RUG01-001275994_2010_0001_AC.pdf
date created
2009-03-25 13:50:34
date last changed
2009-03-25 14:02:51
@phdthesis{530349,
  abstract     = {Water quality criteria setting for metals is hampered by the fact that the bioavailability and hence also the toxicity of many metals is largely influenced by physicochemical parameters such as water hardness, pH and dissolved organic matter. Consequently, a single water quality criterium may be too conservative for certain water bodies whereas it may not be protective enough for other water bodies. This metal-specific issue can be overcome with the development of mathematical models capable of predicting metal bioavailability and toxicity as a function of water chemistry.
In the first part of this doctoral thesis it was investigated to what extent several physicochemical parameters (such as calcium, magnesium, pH, dissolved organic matter) affect the acute and chronic toxicity of nickel to freshwater organisms. For each testing organism (a unicellular green alga, an aquatic invertebrate and a fish) a bioavailability model was developed capable of accurately predicting nickel toxicity in both artificial and natural waters.
An important point of concern was that bioavailability models such as those developed in the first part of this doctoral thesis may underestimate metal toxicity in waters with hardness far below the lower water hardness boundary for which these models were originally developed and validated using {\textquoteleft}standard{\textquoteright} test organisms. In the second part of this research it was therefore investigated whether this concern is scientifically justified for nickel. A series of toxicity tests with field-organisms (microalgae and water fleas) originating from soft and hard surface waters demonstrated that in most cases soft water organisms are equally sensitive to nickel as hard water organisms and that a single bioavailability model can be used to predict the water hardness-dependent toxicity of nickel to soft and hard water organisms.
The data and models generated in this thesis were already used in the European risk assessment of nickel and nickel compounds. The pan-European water quality criterium for nickel will be based on the outcome of this risk assessment. Current developments at the international regulatory level feed the expectation that the application domain of this thesis will further expand.},
  author       = {Deleebeeck, Nele},
  isbn         = {978-90-5989-233-0},
  language     = {eng},
  pages        = {X, 294},
  publisher    = {Ghent University},
  school       = {Ghent University},
  title        = {Bioavailability and toxicity of nickel to freshwater organisms: a modeling approach},
  url          = {http://lib.ugent.be/fulltxt/RUG01/001/275/994/RUG01-001275994\_2010\_0001\_AC.pdf},
  year         = {2008},
}

Chicago
Deleebeeck, Nele. 2008. “Bioavailability and Toxicity of Nickel to Freshwater Organisms: a Modeling Approach”. Gent: Ghent University.
APA
Deleebeeck, N. (2008). Bioavailability and toxicity of nickel to freshwater organisms: a modeling approach. Ghent University, Gent.
Vancouver
1.
Deleebeeck N. Bioavailability and toxicity of nickel to freshwater organisms: a modeling approach. [Gent]: Ghent University; 2008.
MLA
Deleebeeck, Nele. “Bioavailability and Toxicity of Nickel to Freshwater Organisms: a Modeling Approach.” 2008 : n. pag. Print.