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Evaluation of nutritional support in children undergoing haematopoietic stem cell transplantation: a single-centre experience

Sophie Van Lancker (UGent) , Maria Bordon Cueto De Braem (UGent) , JOHAN DE PORRE (UGent) , Barbara De Moerloose (UGent) , Els Vandecruys (UGent) , JORIS VERLOOY (UGent) , Genevieve Laureys (UGent) , Catharina Dhooge (UGent) and Yves Benoit (UGent)
(2008) p.S354-S354
Author
Organization
Abstract
Background: Nutrition is an important aspect in patients undergoing haematopoietic stem cell transplantation (HSCT). Food intake and absorption is impaired due to nausea, mucositis, graft versus host disease and bowel infections. Providing nutritional information to the patient, the parents, and evaluation of the nutritional status of the patient (pt) are main topics for the nurses care program. Objective: Retrospective evaluation of feeding modalities during and after transplantation: frequency of use of nasogastric tube feeding (NGT) and total parenteral nutrition (TPN); timing, duration and eventual influence of TBI. Patients and Methods: Forty seven pts underwent an allogeneic HSCT between 2002-2007. Five patients were excluded because of missing data. Five others were excluded because they didn’t received conditioning therapy. The data were collected from the nurses pt files. The decision to choose TPN or NGT was based on the grade of mucositis, vomiting and age. Results: Thirty four of the thirty seven pts received additional nutrition (TPN or/and NGT) in the period after the transplantation. Three pts, under the age of 2 years, did not need TPN or NGT. The mean age of the pts with TPN was 7.44 years (20 pts), the mean age of the patients who received NGT was 3.53 y (4 pts) and the mean age of pts who received the combination was 9.42 y (10 pts). The mean time to start with TPN was day +3 and it was given for a median of 28 days. Fourteen pts received NGT, 10 of these pts started with NGT after a period of TPN. They started NGT just before discharge (5 pts) or some time after the first discharge (5 pts). The median duration of NGT was 17.5 days. Fifteen pts were transplanted after a TBI-based regimen. These children received TPN during a mean time of 32.6 days, which was not significantly different from the duration of TPN in children without TBI (33.4 days). The duration of need of NGT or TPN was also non-significantly different. At start of TPN there was a mean weight loss of 2% and at start of NGT 4% in relation with the weight at start of the conditioning therapy. At the time of discontinuation of the TPN or NGT, there was not a significant weight gain. Conclusion: Almost all pts undergoing HSCT needed nutritional support, in some of them the NGT was sufficient. The decision to start or to end the additional feeding was not based on weight, but based on the possibility of the patient to achieve an adequate caloric and fluid intake.

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Chicago
Van Lancker, Sophie, Maria Bordon Cueto De Braem, JOHAN DE PORRE, Barbara De Moerloose, Els Vandecruys, JORIS VERLOOY, Genevieve Laureys, Catharina Dhooge, and Yves Benoit. 2008. “Evaluation of Nutritional Support in Children Undergoing Haematopoietic Stem Cell Transplantation: a Single-centre Experience.” In , S354–S354.
APA
Van Lancker, Sophie, Bordon Cueto De Braem, M., DE PORRE, J., De Moerloose, B., Vandecruys, E., VERLOOY, J., Laureys, G., et al. (2008). Evaluation of nutritional support in children undergoing haematopoietic stem cell transplantation: a single-centre experience (pp. S354–S354). Presented at the 34th Annual Meeting of the European Group for Blood and Marrow Transplantation.
Vancouver
1.
Van Lancker S, Bordon Cueto De Braem M, DE PORRE J, De Moerloose B, Vandecruys E, VERLOOY J, et al. Evaluation of nutritional support in children undergoing haematopoietic stem cell transplantation: a single-centre experience. 2008. p. S354–S354.
MLA
Van Lancker, Sophie, Maria Bordon Cueto De Braem, JOHAN DE PORRE, et al. “Evaluation of Nutritional Support in Children Undergoing Haematopoietic Stem Cell Transplantation: a Single-centre Experience.” 2008. S354–S354. Print.
@inproceedings{521361,
  abstract     = {Background: Nutrition is an important aspect in patients undergoing haematopoietic stem cell transplantation (HSCT). Food intake and absorption is impaired due to nausea, mucositis, graft versus host disease and bowel infections. Providing nutritional information to the patient, the parents, and evaluation of the nutritional status of the patient (pt) are main topics for the nurses care program. 
Objective: Retrospective evaluation of feeding modalities during and after transplantation: frequency of use of nasogastric tube feeding (NGT) and total parenteral nutrition (TPN); timing, duration and eventual influence of TBI. 
Patients and Methods: Forty seven pts underwent an allogeneic HSCT between 2002-2007. Five patients were excluded because of missing data. Five others were excluded because they didn{\textquoteright}t received conditioning therapy. The data were collected from the nurses pt files. The decision to choose TPN or NGT was based on the grade of mucositis, vomiting and age. 
Results: Thirty four of the thirty seven pts received additional nutrition (TPN or/and NGT) in the period after the transplantation. Three pts, under the age of 2 years, did not need TPN or NGT. 
The mean age of the pts with TPN was 7.44 years (20 pts), the mean age of the patients who received NGT was 3.53 y (4 pts) and the mean age of pts who received the combination was 9.42 y (10 pts). 
The mean time to start with TPN was day +3 and it was given for a median of 28 days. 
Fourteen pts received NGT, 10 of these pts started with NGT after a period of TPN. They started NGT just before discharge (5 pts) or some time after the first discharge (5 pts). 
The median duration of NGT was 17.5 days. 
Fifteen pts were transplanted after a TBI-based regimen. These children received TPN during a mean time of 32.6 days, which was not significantly different from the duration of TPN in children without TBI (33.4 days). The duration of need of NGT or TPN was also non-significantly different. 
At start of TPN there was a mean weight loss of 2\% and at start of NGT 4\% in relation with the weight at start of the conditioning therapy. At the time of discontinuation of the TPN or NGT, there was not a significant weight gain. 
Conclusion: Almost all pts undergoing HSCT needed nutritional support, in some of them the NGT was sufficient. 
The decision to start or to end the additional feeding was not based on weight, but based on the possibility of the patient to achieve an adequate caloric and fluid intake.},
  author       = {Van Lancker, Sophie and Bordon Cueto De Braem, Maria and DE PORRE, JOHAN and De Moerloose, Barbara and Vandecruys, Els and VERLOOY, JORIS and Laureys, Genevieve and Dhooge, Catharina and Benoit, Yves},
  language     = {eng},
  location     = {Florence, Italy},
  pages        = {S354--S354},
  title        = {Evaluation of nutritional support in children undergoing haematopoietic stem cell transplantation: a single-centre experience},
  year         = {2008},
}