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Validation of an extended method for the detection of the misuse of endogenous steroids in sports, including new hydroxylated metabolites

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Abstract
Endogenous steroids are amongst the most misused doping agents in sports. Their presence poses a major challenge for doping control laboratories. Current threshold levels do not allow for the detection of all endogenous steroid misuse clue to great interindividual variations in urinary steroid concentrations. A method has been developed and validated to screen for traditionally monitored endogenous steroids in doping control as well as specific hydroxylated/oxygenated metabolites in order to enhance the detection capabilities for the misuse of endogenous steroids.
Keywords
EXCRETION, ANDROST-4-ENE-3, TESTOSTERONE, 6, 17-TRIONE, ANABOLIC-STEROIDS, MASS-SPECTROMETRY, DOPING-CONTROL, HELIX-POMATIA, HUMAN URINE, MEN, DEHYDROEPIANDROSTERONE

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Citation

Please use this url to cite or link to this publication:

Chicago
Van Renterghem, Pieter, Peter Van Eenoo, Wim Van Thuyne, Hans Geyer, Wilhelm Schänzer, and Frans Delbeke. 2008. “Validation of an Extended Method for the Detection of the Misuse of Endogenous Steroids in Sports, Including New Hydroxylated Metabolites.” Journal of Chromatography B-analytical Technologies in the Biomedical and Life Sciences 876 (2): 225–235.
APA
Van Renterghem, P., Van Eenoo, P., Van Thuyne, W., Geyer, H., Schänzer, W., & Delbeke, F. (2008). Validation of an extended method for the detection of the misuse of endogenous steroids in sports, including new hydroxylated metabolites. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 876(2), 225–235.
Vancouver
1.
Van Renterghem P, Van Eenoo P, Van Thuyne W, Geyer H, Schänzer W, Delbeke F. Validation of an extended method for the detection of the misuse of endogenous steroids in sports, including new hydroxylated metabolites. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2008;876(2):225–35.
MLA
Van Renterghem, Pieter, Peter Van Eenoo, Wim Van Thuyne, et al. “Validation of an Extended Method for the Detection of the Misuse of Endogenous Steroids in Sports, Including New Hydroxylated Metabolites.” JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 876.2 (2008): 225–235. Print.
@article{496001,
  abstract     = {Endogenous steroids are amongst the most misused doping agents in sports. Their presence poses a major challenge for doping control laboratories. Current threshold levels do not allow for the detection of all endogenous steroid misuse clue to great interindividual variations in urinary steroid concentrations. A method has been developed and validated to screen for traditionally monitored endogenous steroids in doping control as well as specific hydroxylated/oxygenated metabolites in order to enhance the detection capabilities for the misuse of endogenous steroids.},
  author       = {Van Renterghem, Pieter and Van Eenoo, Peter and Van Thuyne, Wim and Geyer, Hans and Sch{\"a}nzer, Wilhelm and Delbeke, Frans},
  issn         = {1570-0232},
  journal      = {JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES},
  language     = {eng},
  number       = {2},
  pages        = {225--235},
  title        = {Validation of an extended method for the detection of the misuse of endogenous steroids in sports, including new hydroxylated metabolites},
  url          = {http://dx.doi.org/10.1016/j.jchromb.2008.10.047},
  volume       = {876},
  year         = {2008},
}

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