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Neural correlates of intentional and stimulus-driven inhibition: a comparison

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The integrative neuroscience of behavioral control (Neuroscience)
Abstract
People can inhibit an action because of an instruction by an external stimulus, or because of their own internal decision. The similarities and differences between these two forms of inhibition are not well understood. Therefore, in the present study the neural correlates of intentional and stimulus-driven inhibition were tested in the same subjects. Participants performed two inhibition tasks while lying in the scanner: the marble task in which they had to choose for themselves between intentionally acting on, or inhibiting a prepotent response to measure intentional inhibition, and the classical stop signal task in which an external signal triggered the inhibition process. Results showed that intentional inhibition decision processes rely on a neural network that has been documented extensively for stimulus-driven inhibition, including bilateral parietal and lateral prefrontal cortex and pre-supplementary motor area. We also found activation in dorsal frontomedian cortex and left inferior frontal gyrus during intentional inhibition that depended on the history of previous choices. Together, these results indicate that intentional inhibition and stimulus-driven inhibition engage a common inhibition network, but intentional inhibition is also characterized by additional context-dependent neural activation in medial prefrontal cortex.
Keywords
RESPONSE-INHIBITION, SELECTION, SIGNAL, STOP, PERFORMANCE, MECHANISMS, MODEL, ACTIVATION, GENERATION, ATTENTION, response inhibition, action, volition, fMRI, cognitive control

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Citation

Please use this url to cite or link to this publication:

Chicago
Schel, Margot A, Simone Kühn, Marcel Brass, Patrick Haggard, K Richard Ridderinkhof, and Eveline A Crone. 2014. “Neural Correlates of Intentional and Stimulus-driven Inhibition: a Comparison.” Frontiers in Human Neuroscience 8.
APA
Schel, M. A., Kühn, S., Brass, M., Haggard, P., Ridderinkhof, K. R., & Crone, E. A. (2014). Neural correlates of intentional and stimulus-driven inhibition: a comparison. FRONTIERS IN HUMAN NEUROSCIENCE, 8.
Vancouver
1.
Schel MA, Kühn S, Brass M, Haggard P, Ridderinkhof KR, Crone EA. Neural correlates of intentional and stimulus-driven inhibition: a comparison. FRONTIERS IN HUMAN NEUROSCIENCE. 2014;8.
MLA
Schel, Margot A et al. “Neural Correlates of Intentional and Stimulus-driven Inhibition: a Comparison.” FRONTIERS IN HUMAN NEUROSCIENCE 8 (2014): n. pag. Print.
@article{4424382,
  abstract     = {People can inhibit an action because of an instruction by an external stimulus, or because of their own internal decision. The similarities and differences between these two forms of inhibition are not well understood. Therefore, in the present study the neural correlates of intentional and stimulus-driven inhibition were tested in the same subjects. Participants performed two inhibition tasks while lying in the scanner: the marble task in which they had to choose for themselves between intentionally acting on, or inhibiting a prepotent response to measure intentional inhibition, and the classical stop signal task in which an external signal triggered the inhibition process. Results showed that intentional inhibition decision processes rely on a neural network that has been documented extensively for stimulus-driven inhibition, including bilateral parietal and lateral prefrontal cortex and pre-supplementary motor area. We also found activation in dorsal frontomedian cortex and left inferior frontal gyrus during intentional inhibition that depended on the history of previous choices. Together, these results indicate that intentional inhibition and stimulus-driven inhibition engage a common inhibition network, but intentional inhibition is also characterized by additional context-dependent neural activation in medial prefrontal cortex.},
  articleno    = {27},
  author       = {Schel, Margot A and Kühn, Simone and Brass, Marcel and Haggard, Patrick and Ridderinkhof, K Richard  and Crone, Eveline A},
  issn         = {1662-5161},
  journal      = {FRONTIERS IN HUMAN NEUROSCIENCE},
  keywords     = {RESPONSE-INHIBITION,SELECTION,SIGNAL,STOP,PERFORMANCE,MECHANISMS,MODEL,ACTIVATION,GENERATION,ATTENTION,response inhibition,action,volition,fMRI,cognitive control},
  language     = {eng},
  pages        = {10},
  title        = {Neural correlates of intentional and stimulus-driven inhibition: a comparison},
  url          = {http://dx.doi.org/10.3389/fnhum.2014.00027},
  volume       = {8},
  year         = {2014},
}

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