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Does contemporary oxygenator design influence haemolysis?

Filip De Somer (UGent)
(2013) PERFUSION-UK. 28(4). p.280-285
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Abstract
Based on their design, all membrane oxygenators generate a certain resistance to flow. In clinical practice, this resistance is calculated by measuring both blood flow and the pressure drop over the oxygenator. Historically, some designs, such as the Kolobow spiral coil oxygenator and the Cobe flat sheet oxygenator, had quite a high pressure drop, but were, nevertheless, considered very haemocompatible. Today, both medium and low pressure drop oxygenators are commercially available. Based on physics and the existing literature, this review aims to investigate whether pressure drop by itself can be considered an independent factor of haemolysis.
Keywords
shear stress, haemolysis, oxygenator, pressure drop, mass transfer, CARDIOPULMONARY BYPASS, MEMBRANE-OXYGENATOR, PRESSURE, FLOWING BLOOD

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Citation

Please use this url to cite or link to this publication:

Chicago
De Somer, Filip. 2013. “Does Contemporary Oxygenator Design Influence Haemolysis?” Perfusion-uk 28 (4): 280–285.
APA
De Somer, F. (2013). Does contemporary oxygenator design influence haemolysis? PERFUSION-UK, 28(4), 280–285.
Vancouver
1.
De Somer F. Does contemporary oxygenator design influence haemolysis? PERFUSION-UK. 2013;28(4):280–5.
MLA
De Somer, Filip. “Does Contemporary Oxygenator Design Influence Haemolysis?” PERFUSION-UK 28.4 (2013): 280–285. Print.
@article{4417989,
  abstract     = {Based on their design, all membrane oxygenators generate a certain resistance to flow. In clinical practice, this resistance is calculated by measuring both blood flow and the pressure drop over the oxygenator. Historically, some designs, such as the Kolobow spiral coil oxygenator and the Cobe flat sheet oxygenator, had quite a high pressure drop, but were, nevertheless, considered very haemocompatible. Today, both medium and low pressure drop oxygenators are commercially available. Based on physics and the existing literature, this review aims to investigate whether pressure drop by itself can be considered an independent factor of haemolysis.},
  author       = {De Somer, Filip},
  issn         = {0267-6591},
  journal      = {PERFUSION-UK},
  keywords     = {shear stress,haemolysis,oxygenator,pressure drop,mass transfer,CARDIOPULMONARY BYPASS,MEMBRANE-OXYGENATOR,PRESSURE,FLOWING BLOOD},
  language     = {eng},
  number       = {4},
  pages        = {280--285},
  title        = {Does contemporary oxygenator design influence haemolysis?},
  url          = {http://dx.doi.org/10.1177/0267659113483803},
  volume       = {28},
  year         = {2013},
}

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