Advanced search
1 file | 111.03 KB Add to list

Voice in female-to-male transsexual persons after long-term androgen therapy

(2014) LARYNGOSCOPE. 124(6). p.1409-1414
Author
Organization
Abstract
Objectives/Hypothesis: The aim of the present study was to 1) document voice in a large sample of female-to-male transsexual persons (FMT), 2) compare their vocal characteristics with those of heterosexual biological males, and 3) determine hormonal factors with impact on their fundamental frequency. Study Design: This was a controlled cross-sectional study. It is the largest study to date on voice and voice change in FMT, and the first to include a control group and FMT who were under long-term androgen administration. Methods: Thirty-eight FMT, ranging in age between 22 and 54 years, and 38 controls, frequency matched by age and smoking behavior, underwent a voice assessment that comprised the determination of pitch, intonation, and perturbation parameters measured during sustained vowel production, counting, and reading. Hormonal factors explored were hematocrit, total testosterone level, luteinizing hormone level, and biallelic mean length of the cytosine-adenine-guanine (CAG) trinucleotide repeat sequence in the androgen receptor gene. Results: It was found that the FMT as a group did not differ significantly from controls for any of the acoustic voice variables studied. However, in about 10% pitch lowering was not totally unproblematic. The lowest-pitched (i.e., more male) voices were observed in FMT with higher hematocrit and longer CAG repeats. Conclusion: After long-term androgen therapy, FMT generally demonstrate an acceptable male voice. Pitch-lowering difficulties can be expected in about 10% of cases and appear, at least in part, to be associated with diminished androgen sensitivity.
Keywords
female-to-male, hormonal factors, voice, Transsexualism, RECEPTOR GENE, SEXUAL DESIRE, MEN, TESTOSTERONE, SENSITIVITY, EXPLORATION, LARYNX, TRACT, MASS, CAG REPEAT POLYMORPHISM

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 111.03 KB

Citation

Please use this url to cite or link to this publication:

MLA
Cosyns, Marjan, John Van Borsel, Katrien Wierckx, et al. “Voice in Female-to-male Transsexual Persons After Long-term Androgen Therapy.” LARYNGOSCOPE 124.6 (2014): 1409–1414. Print.
APA
Cosyns, Marjan, Van Borsel, J., Wierckx, K., Dedecker, D., Van de Peer, F., Daelman, T., Laenen, S., et al. (2014). Voice in female-to-male transsexual persons after long-term androgen therapy. LARYNGOSCOPE, 124(6), 1409–1414. Presented at the 29th World congress of the International Association of Logopedics and Phoniatrics.
Chicago author-date
Cosyns, Marjan, John Van Borsel, Katrien Wierckx, David Dedecker, Fleur Van de Peer, Tine Daelman, Sofie Laenen, and Guy T’Sjoen. 2014. “Voice in Female-to-male Transsexual Persons After Long-term Androgen Therapy.” Laryngoscope 124 (6): 1409–1414.
Chicago author-date (all authors)
Cosyns, Marjan, John Van Borsel, Katrien Wierckx, David Dedecker, Fleur Van de Peer, Tine Daelman, Sofie Laenen, and Guy T’Sjoen. 2014. “Voice in Female-to-male Transsexual Persons After Long-term Androgen Therapy.” Laryngoscope 124 (6): 1409–1414.
Vancouver
1.
Cosyns M, Van Borsel J, Wierckx K, Dedecker D, Van de Peer F, Daelman T, et al. Voice in female-to-male transsexual persons after long-term androgen therapy. LARYNGOSCOPE. 2014;124(6):1409–14.
IEEE
[1]
M. Cosyns et al., “Voice in female-to-male transsexual persons after long-term androgen therapy,” LARYNGOSCOPE, vol. 124, no. 6, pp. 1409–1414, 2014.
@article{4410698,
  abstract     = {Objectives/Hypothesis: The aim of the present study was to 1) document voice in a large sample of female-to-male transsexual persons (FMT), 2) compare their vocal characteristics with those of heterosexual biological males, and 3) determine hormonal factors with impact on their fundamental frequency.
Study Design: This was a controlled cross-sectional study. It is the largest study to date on voice and voice change in FMT, and the first to include a control group and FMT who were under long-term androgen administration.
Methods: Thirty-eight FMT, ranging in age between 22 and 54 years, and 38 controls, frequency matched by age and smoking behavior, underwent a voice assessment that comprised the determination of pitch, intonation, and perturbation parameters measured during sustained vowel production, counting, and reading. Hormonal factors explored were hematocrit, total testosterone level, luteinizing hormone level, and biallelic mean length of the cytosine-adenine-guanine (CAG) trinucleotide repeat sequence in the androgen receptor gene.
Results: It was found that the FMT as a group did not differ significantly from controls for any of the acoustic voice variables studied. However, in about 10% pitch lowering was not totally unproblematic. The lowest-pitched (i.e., more male) voices were observed in FMT with higher hematocrit and longer CAG repeats.
Conclusion: After long-term androgen therapy, FMT generally demonstrate an acceptable male voice. Pitch-lowering difficulties can be expected in about 10% of cases and appear, at least in part, to be associated with diminished androgen sensitivity.},
  author       = {Cosyns, Marjan and Van Borsel, John and Wierckx, Katrien and Dedecker, David and Van de Peer, Fleur and Daelman, Tine and Laenen, Sofie and T'Sjoen, Guy},
  issn         = {0023-852X},
  journal      = {LARYNGOSCOPE},
  keywords     = {female-to-male,hormonal factors,voice,Transsexualism,RECEPTOR GENE,SEXUAL DESIRE,MEN,TESTOSTERONE,SENSITIVITY,EXPLORATION,LARYNX,TRACT,MASS,CAG REPEAT POLYMORPHISM},
  language     = {eng},
  location     = {Turin, Italy},
  number       = {6},
  pages        = {1409--1414},
  title        = {Voice in female-to-male transsexual persons after long-term androgen therapy},
  url          = {http://dx.doi.org/10.1002/lary.24480},
  volume       = {124},
  year         = {2014},
}

Altmetric
View in Altmetric
Web of Science
Times cited: