Synthesis of alkyl 3-chloroazetidine-3-carboxylates via regioselective ring transformation of alkyl 2-(bromomethyl)aziridine-2-carboxylates
- Author
- Asta Žukauskaitė (UGent) , Sven Mangelinckx (UGent) , Algirdas Sackus and Norbert De Kimpe (UGent)
- Organization
- Abstract
- The synthesis of alkyl 3-chloroazetidine-3-carboxylates was developed by ring transformation of alkyl 2-(bromomethyl)aziridine-2-carboxylates utilizing ring opening with hydrochloric acid at the more sterically hindered carbon atom of the aziridine ring and subsequent base-promoted ring closure.
- Keywords
- AZIRIDINES, REARRANGEMENT, CLEAVAGE, ACID, REACTIVITY, AZETIDINE, DERIVATIVES, Ring Transformation, Ring Closure Reaction, Ring Opening Reaction, Azetidine, Aziridine
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-4329033
- MLA
- Žukauskaitė, Asta, et al. “Synthesis of Alkyl 3-Chloroazetidine-3-Carboxylates via Regioselective Ring Transformation of Alkyl 2-(Bromomethyl)Aziridine-2-Carboxylates.” HETEROCYCLES, vol. 88, no. 1, 2014, pp. 731–40, doi:10.3987/COM-13-S(S)35.
- APA
- Žukauskaitė, A., Mangelinckx, S., Sackus, A., & De Kimpe, N. (2014). Synthesis of alkyl 3-chloroazetidine-3-carboxylates via regioselective ring transformation of alkyl 2-(bromomethyl)aziridine-2-carboxylates. HETEROCYCLES, 88(1), 731–740. https://doi.org/10.3987/COM-13-S(S)35
- Chicago author-date
- Žukauskaitė, Asta, Sven Mangelinckx, Algirdas Sackus, and Norbert De Kimpe. 2014. “Synthesis of Alkyl 3-Chloroazetidine-3-Carboxylates via Regioselective Ring Transformation of Alkyl 2-(Bromomethyl)Aziridine-2-Carboxylates.” HETEROCYCLES 88 (1): 731–40. https://doi.org/10.3987/COM-13-S(S)35.
- Chicago author-date (all authors)
- Žukauskaitė, Asta, Sven Mangelinckx, Algirdas Sackus, and Norbert De Kimpe. 2014. “Synthesis of Alkyl 3-Chloroazetidine-3-Carboxylates via Regioselective Ring Transformation of Alkyl 2-(Bromomethyl)Aziridine-2-Carboxylates.” HETEROCYCLES 88 (1): 731–740. doi:10.3987/COM-13-S(S)35.
- Vancouver
- 1.Žukauskaitė A, Mangelinckx S, Sackus A, De Kimpe N. Synthesis of alkyl 3-chloroazetidine-3-carboxylates via regioselective ring transformation of alkyl 2-(bromomethyl)aziridine-2-carboxylates. HETEROCYCLES. 2014;88(1):731–40.
- IEEE
- [1]A. Žukauskaitė, S. Mangelinckx, A. Sackus, and N. De Kimpe, “Synthesis of alkyl 3-chloroazetidine-3-carboxylates via regioselective ring transformation of alkyl 2-(bromomethyl)aziridine-2-carboxylates,” HETEROCYCLES, vol. 88, no. 1, pp. 731–740, 2014.
@article{4329033,
abstract = {{The synthesis of alkyl 3-chloroazetidine-3-carboxylates was developed by ring transformation of alkyl 2-(bromomethyl)aziridine-2-carboxylates utilizing ring opening with hydrochloric acid at the more sterically hindered carbon atom of the aziridine ring and subsequent base-promoted ring closure.}},
author = {{Žukauskaitė, Asta and Mangelinckx, Sven and Sackus, Algirdas and De Kimpe, Norbert}},
issn = {{0385-5414}},
journal = {{HETEROCYCLES}},
keywords = {{AZIRIDINES,REARRANGEMENT,CLEAVAGE,ACID,REACTIVITY,AZETIDINE,DERIVATIVES,Ring Transformation,Ring Closure Reaction,Ring Opening Reaction,Azetidine,Aziridine}},
language = {{eng}},
number = {{1}},
pages = {{731--740}},
title = {{Synthesis of alkyl 3-chloroazetidine-3-carboxylates via regioselective ring transformation of alkyl 2-(bromomethyl)aziridine-2-carboxylates}},
url = {{http://doi.org/10.3987/COM-13-S(S)35}},
volume = {{88}},
year = {{2014}},
}
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