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Pharmacokinetics in special populations

Italo Poggesi, Margherita Strolin Benedetti, Rhys Whomsley, Sophie Le Lamer, Mathieu Molimard and Jean-Baptiste Watelet UGent (2009) DRUG METABOLISM REVIEWS. 41(3). p.422-454
abstract
Pharmacokinetics are typically dependent on a variety of physiological variables (e.g., age, ethnicity, or pregnancy) or pathological conditions (e.g., renal and hepatic insufficiency, cardiac dysfunction, obesity, etc.). The influence of some of these conditions has not always been thoroughly assessed in the clinical studies of antiallergic drugs. However, the knowledge of the physiological grounds of the pharmacokinetics can provide some insight for predicting the potential alterations and guiding the initial prescription strategies. It is important to recognize that both pharmacokinetic and pharmacodynamic differences between populations should be considered. The available information on drugs used for the therapy of allergic diseases is reviewed in this chapter.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
pharmacokinetics, pharmacodynamics, Antiallergic drugs, renal impairment, hepatic impairment, demographic covariates, pregnancy, milk transfer, LIVER ALCOHOL-DEHYDROGENASE, CONGESTIVE HEART-FAILURE, CHRONIC-RENAL-FAILURE, FUROATE NASAL SPRAY, HEALTHY JAPANESE VOLUNTEERS, PERENNIAL ALLERGIC RHINITIS, HEPATIC DRUG-METABOLISM, HISTAMINE-INDUCED WHEAL, CLINICAL-PHARMACOLOGY, HUMAN PLACENTA
journal title
DRUG METABOLISM REVIEWS
Drug Metab. Rev.
volume
41
issue
3
pages
422 - 454
Web of Science type
Review
Web of Science id
000269410900007
JCR category
PHARMACOLOGY & PHARMACY
JCR impact factor
5.439 (2009)
JCR rank
15/236 (2009)
JCR quartile
1 (2009)
ISSN
0360-2532
DOI
10.1080/10837450902891527
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
4324915
handle
http://hdl.handle.net/1854/LU-4324915
date created
2014-03-07 09:35:51
date last changed
2016-12-19 15:46:57
@article{4324915,
  abstract     = {Pharmacokinetics are typically dependent on a variety of physiological variables (e.g., age, ethnicity, or pregnancy) or pathological conditions (e.g., renal and hepatic insufficiency, cardiac dysfunction, obesity, etc.). The influence of some of these conditions has not always been thoroughly assessed in the clinical studies of antiallergic drugs. However, the knowledge of the physiological grounds of the pharmacokinetics can provide some insight for predicting the potential alterations and guiding the initial prescription strategies. It is important to recognize that both pharmacokinetic and pharmacodynamic differences between populations should be considered. The available information on drugs used for the therapy of allergic diseases is reviewed in this chapter.},
  author       = {Poggesi, Italo and Benedetti, Margherita Strolin and Whomsley, Rhys and Le Lamer, Sophie and Molimard, Mathieu and Watelet, Jean-Baptiste},
  issn         = {0360-2532},
  journal      = {DRUG METABOLISM REVIEWS},
  keyword      = {pharmacokinetics,pharmacodynamics,Antiallergic drugs,renal impairment,hepatic impairment,demographic covariates,pregnancy,milk transfer,LIVER ALCOHOL-DEHYDROGENASE,CONGESTIVE HEART-FAILURE,CHRONIC-RENAL-FAILURE,FUROATE NASAL SPRAY,HEALTHY JAPANESE VOLUNTEERS,PERENNIAL ALLERGIC RHINITIS,HEPATIC DRUG-METABOLISM,HISTAMINE-INDUCED WHEAL,CLINICAL-PHARMACOLOGY,HUMAN PLACENTA},
  language     = {eng},
  number       = {3},
  pages        = {422--454},
  title        = {Pharmacokinetics in special populations},
  url          = {http://dx.doi.org/10.1080/10837450902891527},
  volume       = {41},
  year         = {2009},
}

Chicago
Poggesi, Italo, Margherita Strolin Benedetti, Rhys Whomsley, Sophie Le Lamer, Mathieu Molimard, and Jean-Baptiste Watelet. 2009. “Pharmacokinetics in Special Populations.” Drug Metabolism Reviews 41 (3): 422–454.
APA
Poggesi, I., Benedetti, M. S., Whomsley, R., Le Lamer, S., Molimard, M., & Watelet, J.-B. (2009). Pharmacokinetics in special populations. DRUG METABOLISM REVIEWS, 41(3), 422–454.
Vancouver
1.
Poggesi I, Benedetti MS, Whomsley R, Le Lamer S, Molimard M, Watelet J-B. Pharmacokinetics in special populations. DRUG METABOLISM REVIEWS. 2009;41(3):422–54.
MLA
Poggesi, Italo, Margherita Strolin Benedetti, Rhys Whomsley, et al. “Pharmacokinetics in Special Populations.” DRUG METABOLISM REVIEWS 41.3 (2009): 422–454. Print.