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Regulated necrosis: the expanding network of non-apoptotic cell death pathways

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Ghent researchers on unfolded proteins in inflammatory disease (GROUP-ID)
Abstract
Cell death research was revitalized by the understanding that necrosis can occur in a highly regulated and genetically controlled manner. Although RIPK1 (receptor-interacting protein kinase 1)- and RIPK3-MLKL (mixed lineage kinase domain-like)-mediated necroptosis is the most understood form of regulated necrosis, other examples of this process are emerging, including cell death mechanisms known as parthanatos, oxytosis, ferroptosis, NETosis, pyronecrosis and pyroptosis. Elucidating how these pathways of regulated necrosis are interconnected at the molecular level should enable this process to be therapeutically targeted.
Keywords
MIXED LINEAGE KINASE, MITOCHONDRIAL PERMEABILITY TRANSITION, KAPPA-B ACTIVATION, DOMAIN-LIKE PROTEIN, ISCHEMIA-REPERFUSION INJURY, ALPHA-DEPENDENT APOPTOSIS, TNF-INDUCED NECROPTOSIS, CYCLOPHILIN-D, IN-VIVO, PROGRAMMED NECROSIS

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Citation

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MLA
Vanden Berghe, Tom, Andreas Linkermann, Sandrine Jouan-Lanhouet, et al. “Regulated Necrosis: The Expanding Network of Non-apoptotic Cell Death Pathways.” NATURE REVIEWS MOLECULAR CELL BIOLOGY 15.2 (2014): 134–146. Print.
APA
Vanden Berghe, T., Linkermann, A., Jouan-Lanhouet, S., Walczak, H., & Vandenabeele, P. (2014). Regulated necrosis: the expanding network of non-apoptotic cell death pathways. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 15(2), 134–146.
Chicago author-date
Vanden Berghe, Tom, Andreas Linkermann, Sandrine Jouan-Lanhouet, Henning Walczak, and Peter Vandenabeele. 2014. “Regulated Necrosis: The Expanding Network of Non-apoptotic Cell Death Pathways.” Nature Reviews Molecular Cell Biology 15 (2): 134–146.
Chicago author-date (all authors)
Vanden Berghe, Tom, Andreas Linkermann, Sandrine Jouan-Lanhouet, Henning Walczak, and Peter Vandenabeele. 2014. “Regulated Necrosis: The Expanding Network of Non-apoptotic Cell Death Pathways.” Nature Reviews Molecular Cell Biology 15 (2): 134–146.
Vancouver
1.
Vanden Berghe T, Linkermann A, Jouan-Lanhouet S, Walczak H, Vandenabeele P. Regulated necrosis: the expanding network of non-apoptotic cell death pathways. NATURE REVIEWS MOLECULAR CELL BIOLOGY. 2014;15(2):134–46.
IEEE
[1]
T. Vanden Berghe, A. Linkermann, S. Jouan-Lanhouet, H. Walczak, and P. Vandenabeele, “Regulated necrosis: the expanding network of non-apoptotic cell death pathways,” NATURE REVIEWS MOLECULAR CELL BIOLOGY, vol. 15, no. 2, pp. 134–146, 2014.
@article{4322451,
  abstract     = {Cell death research was revitalized by the understanding that necrosis can occur in a highly regulated and genetically controlled manner. Although RIPK1 (receptor-interacting protein kinase 1)- and RIPK3-MLKL (mixed lineage kinase domain-like)-mediated necroptosis is the most understood form of regulated necrosis, other examples of this process are emerging, including cell death mechanisms known as parthanatos, oxytosis, ferroptosis, NETosis, pyronecrosis and pyroptosis. Elucidating how these pathways of regulated necrosis are interconnected at the molecular level should enable this process to be therapeutically targeted.},
  author       = {Vanden Berghe, Tom and Linkermann, Andreas and Jouan-Lanhouet, Sandrine and Walczak, Henning and Vandenabeele, Peter},
  issn         = {1471-0072},
  journal      = {NATURE REVIEWS MOLECULAR CELL BIOLOGY},
  keywords     = {MIXED LINEAGE KINASE,MITOCHONDRIAL PERMEABILITY TRANSITION,KAPPA-B ACTIVATION,DOMAIN-LIKE PROTEIN,ISCHEMIA-REPERFUSION INJURY,ALPHA-DEPENDENT APOPTOSIS,TNF-INDUCED NECROPTOSIS,CYCLOPHILIN-D,IN-VIVO,PROGRAMMED NECROSIS},
  language     = {eng},
  number       = {2},
  pages        = {134--146},
  title        = {Regulated necrosis: the expanding network of non-apoptotic cell death pathways},
  url          = {http://dx.doi.org/10.1038/nrm3737},
  volume       = {15},
  year         = {2014},
}

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