Advanced search
1 file | 549.12 KB
Author
Organization
Abstract
Folate deficiency is a global health problem affecting many people in the developing and developed world. Current interventions (industrial food fortification and supplementation by folic acid pills) are effective if they can be used but might not be possible in less developed countries. Recent advances demonstrate that folate biofortification of food crops is now a feasible complementary strategy to fight folate deficiency worldwide. The genes and enzymes of folate synthesis are sufficiently understood to enable metabolic engineering of the pathway, and results from pilot engineering studies in plants (and bacteria) are encouraging. Here, we review the current status of investigations in the field of folate enhancement on the eve of a new era in food fortification.
Keywords
ONE-CARBON METABOLISM, NEURAL-TUBE DEFECTS, GAMMA-GLUTAMYL HYDROLASES, FOLIC-ACID INTAKE, UNITED-STATES, MICRONUTRIENT MALNUTRITION, PLASMA HOMOCYSTEINE, LACTOCOCCUS-LACTIS, GOLDEN RICE, FORTIFICATION

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 549.12 KB

Citation

Please use this url to cite or link to this publication:

Chicago
Bekaert, Samir, Serguei Storojenko, Payam Mehrshah, Malcolm J Bennett, Willy Lambert, Jesse F Gregory III, Karel Schubert, Jeroen Hugenholtz, Dominique Van Der Straeten, and Andrew D Hanson. 2008. “Folate Biofortification in Food Plants.” Trends in Plant Science 13 (1): 28–35.
APA
Bekaert, Samir, Storojenko, S., Mehrshah, P., Bennett, M. J., Lambert, W., Gregory, J. F., III, Schubert, K., et al. (2008). Folate biofortification in food plants. TRENDS IN PLANT SCIENCE, 13(1), 28–35.
Vancouver
1.
Bekaert S, Storojenko S, Mehrshah P, Bennett MJ, Lambert W, Gregory JF III, et al. Folate biofortification in food plants. TRENDS IN PLANT SCIENCE. 2008;13(1):28–35.
MLA
Bekaert, Samir, Serguei Storojenko, Payam Mehrshah, et al. “Folate Biofortification in Food Plants.” TRENDS IN PLANT SCIENCE 13.1 (2008): 28–35. Print.
@article{428235,
  abstract     = {Folate deficiency is a global health problem affecting many people in the developing and developed world. Current interventions (industrial food fortification and supplementation by folic acid pills) are effective if they can be used but might not be possible in less developed countries. Recent advances demonstrate that folate biofortification of food crops is now a feasible complementary strategy to fight folate deficiency worldwide. The genes and enzymes of folate synthesis are sufficiently understood to enable metabolic engineering of the pathway, and results from pilot engineering studies in plants (and bacteria) are encouraging. Here, we review the current status of investigations in the field of folate enhancement on the eve of a new era in food fortification.},
  author       = {Bekaert, Samir and Storojenko, Serguei and Mehrshah, Payam and Bennett, Malcolm J and Lambert, Willy and Gregory, Jesse F, III and Schubert, Karel and Hugenholtz, Jeroen and Van Der Straeten, Dominique and Hanson, Andrew D},
  issn         = {1360-1385},
  journal      = {TRENDS IN PLANT SCIENCE},
  keyword      = {ONE-CARBON METABOLISM,NEURAL-TUBE DEFECTS,GAMMA-GLUTAMYL HYDROLASES,FOLIC-ACID INTAKE,UNITED-STATES,MICRONUTRIENT MALNUTRITION,PLASMA HOMOCYSTEINE,LACTOCOCCUS-LACTIS,GOLDEN RICE,FORTIFICATION},
  language     = {eng},
  number       = {1},
  pages        = {28--35},
  title        = {Folate biofortification in food plants},
  url          = {http://dx.doi.org/10.1016/j.tplants.2007.11.001},
  volume       = {13},
  year         = {2008},
}

Altmetric
View in Altmetric
Web of Science
Times cited: