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Eosinophilic granuloma: a different behaviour in children than in adults

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Abstract
Localised Langerhans-cell histiocytosis of bone (eosinophilic granuloma) is a benign tumour-like condition with a variable clinical course. Different forms of treatment have been reported to give satisfactory results. However, previous series all contain patients with a wide age range. Our aim was to investigate the effect of skeletal maturity on the rate of recurrence of isolated eosinophilic granuloma of bone excluding those arising in the spine. We followed up 32 patients with an isolated eosinophilic granuloma for a mean of five years; 17 were skeletally immature. No recurrences were noted in the skeletally immature group even after biopsy alone. By contrast, four of 13 skeletally mature patients had a recurrence and required further surgery. This suggests that eosinophilic granuloma has a low rate of recurrence in skeletally immature patients.
Keywords
BONE, LANGERHANS-CELL HISTIOCYTOSIS

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MLA
Plasschaert, Frank, C Craig, R Bell, et al. “Eosinophilic Granuloma: a Different Behaviour in Children Than in Adults.” JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 84B.6 (2002): 870–872. Print.
APA
Plasschaert, Frank, Craig, C., Bell, R., Cole, W., Wunder, J., & Alman, B. (2002). Eosinophilic granuloma: a different behaviour in children than in adults. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 84B(6), 870–872.
Chicago author-date
Plasschaert, Frank, C Craig, R Bell, WG Cole, JS Wunder, and BA Alman. 2002. “Eosinophilic Granuloma: a Different Behaviour in Children Than in Adults.” Journal of Bone and Joint Surgery-british Volume 84B (6): 870–872.
Chicago author-date (all authors)
Plasschaert, Frank, C Craig, R Bell, WG Cole, JS Wunder, and BA Alman. 2002. “Eosinophilic Granuloma: a Different Behaviour in Children Than in Adults.” Journal of Bone and Joint Surgery-british Volume 84B (6): 870–872.
Vancouver
1.
Plasschaert F, Craig C, Bell R, Cole W, Wunder J, Alman B. Eosinophilic granuloma: a different behaviour in children than in adults. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME. 2002;84B(6):870–2.
IEEE
[1]
F. Plasschaert, C. Craig, R. Bell, W. Cole, J. Wunder, and B. Alman, “Eosinophilic granuloma: a different behaviour in children than in adults,” JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, vol. 84B, no. 6, pp. 870–872, 2002.
@article{4267024,
  abstract     = {Localised Langerhans-cell histiocytosis of bone (eosinophilic granuloma) is a benign tumour-like condition with a variable clinical course. Different forms of treatment have been reported to give satisfactory results. However, previous series all contain patients with a wide age range. Our aim was to investigate the effect of skeletal maturity on the rate of recurrence of isolated eosinophilic granuloma of bone excluding those arising in the spine.
We followed up 32 patients with an isolated eosinophilic granuloma for a mean of five years; 17 were skeletally immature. No recurrences were noted in the skeletally immature group even after biopsy alone. By contrast, four of 13 skeletally mature patients had a recurrence and required further surgery. This suggests that eosinophilic granuloma has a low rate of recurrence in skeletally immature patients.},
  author       = {Plasschaert, Frank and Craig, C and Bell, R and Cole, WG and Wunder, JS and Alman, BA},
  issn         = {0301-620X},
  journal      = {JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME},
  keywords     = {BONE,LANGERHANS-CELL HISTIOCYTOSIS},
  language     = {eng},
  number       = {6},
  pages        = {870--872},
  title        = {Eosinophilic granuloma: a different behaviour in children than in adults},
  url          = {http://dx.doi.org/10.1302/0301-620X.84B6.12585},
  volume       = {84B},
  year         = {2002},
}

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