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Animal models for studying female genital tract infection with Chlamydia trachomatis

(2013) INFECTION AND IMMUNITY. 81(9). p.3060-3067
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Abstract
Chlamydia trachomatis is a Gram-negative obligate intracellular bacterial pathogen. It is the leading cause of bacterial sexually transmitted disease in the world, with more than 100 million new cases of genital tract infections with C. trachomatis occurring each year. Animal models are indispensable for the study of C. trachomatis infections and the development and evaluation of candidate vaccines. In this paper, the most commonly used animal models to study female genital tract infections with C. trachomatis will be reviewed, namely, the mouse, guinea pig, and nonhuman primate models. Additionally, we will focus on the more recently developed pig model.
Keywords
CD4(+) T-CELLS, PIG INCLUSION CONJUNCTIVITIS, GENE KNOCKOUT MICE, REPRODUCTIVE-TRACT, GAMMA-INTERFERON, PELVIC-INFLAMMATORY-DISEASE, GUINEA-PIGS, MOUSE PNEUMONITIS, IMMUNE-RESPONSE, TAILED MACAQUES

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Chicago
De Clercq, Evelien, Isabelle Kalmar, and Daisy Vanrompay. 2013. “Animal Models for Studying Female Genital Tract Infection with Chlamydia Trachomatis.” Infection and Immunity 81 (9): 3060–3067.
APA
De Clercq, Evelien, Kalmar, I., & Vanrompay, D. (2013). Animal models for studying female genital tract infection with Chlamydia trachomatis. INFECTION AND IMMUNITY, 81(9), 3060–3067.
Vancouver
1.
De Clercq E, Kalmar I, Vanrompay D. Animal models for studying female genital tract infection with Chlamydia trachomatis. INFECTION AND IMMUNITY. 2013;81(9):3060–7.
MLA
De Clercq, Evelien, Isabelle Kalmar, and Daisy Vanrompay. “Animal Models for Studying Female Genital Tract Infection with Chlamydia Trachomatis.” INFECTION AND IMMUNITY 81.9 (2013): 3060–3067. Print.
@article{4265310,
  abstract     = {Chlamydia trachomatis is a Gram-negative obligate intracellular bacterial pathogen. It is the leading cause of bacterial sexually transmitted disease in the world, with more than 100 million new cases of genital tract infections with C. trachomatis occurring each year. Animal models are indispensable for the study of C. trachomatis infections and the development and evaluation of candidate vaccines. In this paper, the most commonly used animal models to study female genital tract infections with C. trachomatis will be reviewed, namely, the mouse, guinea pig, and nonhuman primate models. Additionally, we will focus on the more recently developed pig model.},
  author       = {De Clercq, Evelien and Kalmar, Isabelle and Vanrompay, Daisy},
  issn         = {0019-9567},
  journal      = {INFECTION AND IMMUNITY},
  keywords     = {CD4(+) T-CELLS,PIG INCLUSION CONJUNCTIVITIS,GENE KNOCKOUT MICE,REPRODUCTIVE-TRACT,GAMMA-INTERFERON,PELVIC-INFLAMMATORY-DISEASE,GUINEA-PIGS,MOUSE PNEUMONITIS,IMMUNE-RESPONSE,TAILED MACAQUES},
  language     = {eng},
  number       = {9},
  pages        = {3060--3067},
  title        = {Animal models for studying female genital tract infection with Chlamydia trachomatis},
  url          = {http://dx.doi.org/10.1128/IAI.00357-13},
  volume       = {81},
  year         = {2013},
}

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