MT1 melatonin receptor expression in Warthin's tumor
- Author
- José Aneiros-Fernández, Salvador Arias-Santiago, Borga Arias-Santiago, Maria Herrero-Fernández, Víctor Sebastián Carriel Araya (UGent) , Jose Aneiros, Antonio López-Valverde and Antonio Cutando-Soriano
- Organization
- Abstract
- We contribute the first immunohistochemical study of MT1 melatonin receptor in Warthin's tumor and normal parotid gland. All 14 Warthin's tumors studied showed intense cytoplasmic positivity for MT1 receptor in all cylindrical epithelial cells lining spaces and a less intense positivity in basal cells. The lymphoid component accompanying the tumor was always negative for MT1 receptor. The parotid structure surrounding the tumor showed intense cytoplasmic positivity in all cells lining excretory ducts (lobar and lobulillar), with a lesser and focal positivity in cells of the acinar component. The biological activity of MT1 receptor in epithelial cells lining parotid excretory ducts may resemble its activity in Warthin's tumor cells. Hence, we propose Warthin's tumor as a useful positive control in immunohistochemical studies of MT1 melatonin receptor.
- Keywords
- Melatonin, Immunohistochemistry, MT1 receptor, Normal parotid gland, BREAST-CANCER CELLS, CLINICAL-RELEVANCE, SUBTYPE, TISSUE, RAT
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-4251247
- MLA
- Aneiros-Fernández, José, et al. “MT1 Melatonin Receptor Expression in Warthin’s Tumor.” PATHOLOGY ONCOLOGY RESEARCH, vol. 19, no. 2, 2013, pp. 247–50, doi:10.1007/s12253-012-9575-z.
- APA
- Aneiros-Fernández, J., Arias-Santiago, S., Arias-Santiago, B., Herrero-Fernández, M., Carriel Araya, V. S., Aneiros, J., … Cutando-Soriano, A. (2013). MT1 melatonin receptor expression in Warthin’s tumor. PATHOLOGY ONCOLOGY RESEARCH, 19(2), 247–250. https://doi.org/10.1007/s12253-012-9575-z
- Chicago author-date
- Aneiros-Fernández, José, Salvador Arias-Santiago, Borga Arias-Santiago, Maria Herrero-Fernández, Víctor Sebastián Carriel Araya, Jose Aneiros, Antonio López-Valverde, and Antonio Cutando-Soriano. 2013. “MT1 Melatonin Receptor Expression in Warthin’s Tumor.” PATHOLOGY ONCOLOGY RESEARCH 19 (2): 247–50. https://doi.org/10.1007/s12253-012-9575-z.
- Chicago author-date (all authors)
- Aneiros-Fernández, José, Salvador Arias-Santiago, Borga Arias-Santiago, Maria Herrero-Fernández, Víctor Sebastián Carriel Araya, Jose Aneiros, Antonio López-Valverde, and Antonio Cutando-Soriano. 2013. “MT1 Melatonin Receptor Expression in Warthin’s Tumor.” PATHOLOGY ONCOLOGY RESEARCH 19 (2): 247–250. doi:10.1007/s12253-012-9575-z.
- Vancouver
- 1.Aneiros-Fernández J, Arias-Santiago S, Arias-Santiago B, Herrero-Fernández M, Carriel Araya VS, Aneiros J, et al. MT1 melatonin receptor expression in Warthin’s tumor. PATHOLOGY ONCOLOGY RESEARCH. 2013;19(2):247–50.
- IEEE
- [1]J. Aneiros-Fernández et al., “MT1 melatonin receptor expression in Warthin’s tumor,” PATHOLOGY ONCOLOGY RESEARCH, vol. 19, no. 2, pp. 247–250, 2013.
@article{4251247,
abstract = {{We contribute the first immunohistochemical study of MT1 melatonin receptor in Warthin's tumor and normal parotid gland. All 14 Warthin's tumors studied showed intense cytoplasmic positivity for MT1 receptor in all cylindrical epithelial cells lining spaces and a less intense positivity in basal cells. The lymphoid component accompanying the tumor was always negative for MT1 receptor. The parotid structure surrounding the tumor showed intense cytoplasmic positivity in all cells lining excretory ducts (lobar and lobulillar), with a lesser and focal positivity in cells of the acinar component. The biological activity of MT1 receptor in epithelial cells lining parotid excretory ducts may resemble its activity in Warthin's tumor cells. Hence, we propose Warthin's tumor as a useful positive control in immunohistochemical studies of MT1 melatonin receptor.}},
author = {{Aneiros-Fernández, José and Arias-Santiago, Salvador and Arias-Santiago, Borga and Herrero-Fernández, Maria and Carriel Araya, Víctor Sebastián and Aneiros, Jose and López-Valverde, Antonio and Cutando-Soriano, Antonio}},
issn = {{1219-4956}},
journal = {{PATHOLOGY ONCOLOGY RESEARCH}},
keywords = {{Melatonin,Immunohistochemistry,MT1 receptor,Normal parotid gland,BREAST-CANCER CELLS,CLINICAL-RELEVANCE,SUBTYPE,TISSUE,RAT}},
language = {{eng}},
number = {{2}},
pages = {{247--250}},
title = {{MT1 melatonin receptor expression in Warthin's tumor}},
url = {{http://doi.org/10.1007/s12253-012-9575-z}},
volume = {{19}},
year = {{2013}},
}
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