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EQ-5D versus SF-12 in coronary patients: are they interchangeable?

Delphine De Smedt (UGent) , Els Clays (UGent) , Lieven Annemans (UGent) and Dirk De Bacquer (UGent)
(2014) VALUE IN HEALTH. 17(1). p.84-89
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Organization
Abstract
Objectives: The aim of this study was to compare EuroQol five-dimensional (EQ-5D) utility scores and six-dimensional health state classification (SF-6D) utility scores (derived from the 12-Item Short-Form Health Survey [SF-12]) by using a large European sample of patients with stable coronary heart disease. Special attention was given to country specific results. Methods: Data from the EURopean Action on Secondary and Primary Prevention by Intervention to Reduce Events III (EUROASPIRE III) survey were used. Patients hospitalized for a coronary artery bypass graft, percutaneous coronary intervention, acute myocardial infarction, or myocardial ischemia were interviewed and examined at least 6 months after their acute event. Health related quality of life was assessed by using the EQ-5D and the SF-12. SF-12 outcomes were converted to SF-6D utility values, allowing comparison between both measures. Results: Both EQ-5D and SF-6D results were available for 7472 patients with coronary heart disease from 20 European countries. The measures were significantly correlated (intraclass correlation coefficient = 0.536); however, large differences between the two measures remain. A total of 28.8% of the patients reported a ceiling effect on the EQ-5D instrument, whereas only 4.2% of the patients reported full health based on the SF-6D. Especially the mental component does not seem to be completely captured by the EQ-5D instrument Furthermore, patients with worse EQ-5D outcomes were more likely to have better SF CD results, whereas patients with better EQ-5D outcomes were more likely to have worse SF-6D results. Conclusions: Both measures are not interchangeable. Whereas the main disadvantage of the EQ-5D questionnaire is its ceiling effect, the potential advantages of SF-12 might disappear when converting the outcomes into an SF-6D utility, because of the small differences between patients.
Keywords
EQ-5D, coronary heart disease, health-related quality of life, SF-12, utility, HEART-DISEASE, HEALTH-STATUS, COST-UTILITY, SF-6D, PREFERENCES, POPULATION, INFARCTION, STATES

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Citation

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MLA
De Smedt, Delphine, Els Clays, Lieven Annemans, et al. “EQ-5D Versus SF-12 in Coronary Patients: Are They Interchangeable?” VALUE IN HEALTH 17.1 (2014): 84–89. Print.
APA
De Smedt, D., Clays, E., Annemans, L., & De Bacquer, D. (2014). EQ-5D versus SF-12 in coronary patients: are they interchangeable? VALUE IN HEALTH, 17(1), 84–89.
Chicago author-date
De Smedt, Delphine, Els Clays, Lieven Annemans, and Dirk De Bacquer. 2014. “EQ-5D Versus SF-12 in Coronary Patients: Are They Interchangeable?” Value in Health 17 (1): 84–89.
Chicago author-date (all authors)
De Smedt, Delphine, Els Clays, Lieven Annemans, and Dirk De Bacquer. 2014. “EQ-5D Versus SF-12 in Coronary Patients: Are They Interchangeable?” Value in Health 17 (1): 84–89.
Vancouver
1.
De Smedt D, Clays E, Annemans L, De Bacquer D. EQ-5D versus SF-12 in coronary patients: are they interchangeable? VALUE IN HEALTH. 2014;17(1):84–9.
IEEE
[1]
D. De Smedt, E. Clays, L. Annemans, and D. De Bacquer, “EQ-5D versus SF-12 in coronary patients: are they interchangeable?,” VALUE IN HEALTH, vol. 17, no. 1, pp. 84–89, 2014.
@article{4250184,
  abstract     = {Objectives: The aim of this study was to compare EuroQol five-dimensional (EQ-5D) utility scores and six-dimensional health state classification (SF-6D) utility scores (derived from the 12-Item Short-Form Health Survey [SF-12]) by using a large European sample of patients with stable coronary heart disease. Special attention was given to country specific results.
Methods: Data from the EURopean Action on Secondary and Primary Prevention by Intervention to Reduce Events III (EUROASPIRE III) survey were used. Patients hospitalized for a coronary artery bypass graft, percutaneous coronary intervention, acute myocardial infarction, or myocardial ischemia were interviewed and examined at least 6 months after their acute event. Health related quality of life was assessed by using the EQ-5D and the SF-12. SF-12 outcomes were converted to SF-6D utility values, allowing comparison between both measures.
Results: Both EQ-5D and SF-6D results were available for 7472 patients with coronary heart disease from 20 European countries. The measures were significantly correlated (intraclass correlation coefficient = 0.536); however, large differences between the two measures remain. A total of 28.8% of the patients reported a ceiling effect on the EQ-5D instrument, whereas only 4.2% of the patients reported full health based on the SF-6D. Especially the mental component does not seem to be completely captured by the EQ-5D instrument Furthermore, patients with worse EQ-5D outcomes were more likely to have better SF CD results, whereas patients with better EQ-5D outcomes were more likely to have worse SF-6D results.
Conclusions: Both measures are not interchangeable. Whereas the main disadvantage of the EQ-5D questionnaire is its ceiling effect, the potential advantages of SF-12 might disappear when converting the outcomes into an SF-6D utility, because of the small differences between patients.},
  author       = {De Smedt, Delphine and Clays, Els and Annemans, Lieven and De Bacquer, Dirk},
  issn         = {1098-3015},
  journal      = {VALUE IN HEALTH},
  keywords     = {EQ-5D,coronary heart disease,health-related quality of life,SF-12,utility,HEART-DISEASE,HEALTH-STATUS,COST-UTILITY,SF-6D,PREFERENCES,POPULATION,INFARCTION,STATES},
  language     = {eng},
  number       = {1},
  pages        = {84--89},
  title        = {EQ-5D versus SF-12 in coronary patients: are they interchangeable?},
  url          = {http://dx.doi.org/10.1016/j.jval.2013.10.010},
  volume       = {17},
  year         = {2014},
}

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