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Silicon nanophotonic ring resonators sensors integrated in reaction tubes

Cristina Lerma Arce, Arne Goes, Elewout Hallynck UGent, Peter Dubruel UGent, Katarzyna Komorowska UGent, Steven Van Put UGent and Peter Bienstman UGent (2013) Proceedings of SPIE. 8598.
abstract
Enzyme-linked immunosorbent assays (ELISA) are the most popular immunoassay techniques performed every day in hospitals and laboratories and they are used as a diagnostic tool in medicine and plant pathology, as well as a quality-control check in various industries. However, complex labeling techniques are required to be able to perform the assay and non-specific binding and endpoint timing are difficult to optimize. These issues could be solved by label-free techniques such as silicon nanophotonic microring resonator sensors, but this platform requires complex microfluidics, which is very much removed from the daily practice in e. g. hospital labs, which still relies to a large degree on platforms like 96-well microtiter plates or reaction tubes. To address these issues, here, we propose the combination of a simple and compatible reaction tube platform with label free silicon-on-insulator (SOI) photonic biosensors, where the flow is through the sensor chip as opposed to over the chip as in more conventional approaches. This device allows real time detection and analysis. Its great flexibility and small footprint make it ideal for an easy handling in any laboratory.
Please use this url to cite or link to this publication:
author
organization
year
type
conference (proceedingsPaper)
publication status
published
subject
keyword
photonic microring resonators, Silicon nanophotonic sensors, Silicon-on-Insulator (SOI), reaction tubes, Enzyme-linked immunosorbert assay (ELISA)
in
Proceedings of SPIE
volume
8598
issue title
BIOINSPIRED, BIOINTEGRATED, BIOENGINEERED PHOTONIC DEVICES
article number
85980I
pages
7 pages
publisher
Spie
conference name
Conference on Bioinspired, Biointegrated, Bioengineered Photonic Devices
conference location
San Francisco, California
conference start
2013-02-02
conference end
2013-02-07
Web of Science type
Proceedings Paper
Web of Science id
000322111400005
ISSN
0277-786X
DOI
10.1117/12.2003970
project
Center for nano- and biophotonics (NB-Photonics)
language
English
UGent publication?
yes
classification
P1
copyright statement
I have transferred the copyright for this publication to the publisher
id
4245457
handle
http://hdl.handle.net/1854/LU-4245457
date created
2014-01-23 08:39:43
date last changed
2016-12-21 15:41:01
@inproceedings{4245457,
  abstract     = {Enzyme-linked immunosorbent assays (ELISA) are the most popular immunoassay techniques performed every day in hospitals and laboratories and they are used as a diagnostic tool in medicine and plant pathology, as well as a quality-control check in various industries. However, complex labeling techniques are required to be able to perform the assay and non-specific binding and endpoint timing are difficult to optimize. These issues could be solved by label-free techniques such as silicon nanophotonic microring resonator sensors, but this platform requires complex microfluidics, which is very much removed from the daily practice in e. g. hospital labs, which still relies to a large degree on platforms like 96-well microtiter plates or reaction tubes. To address these issues, here, we propose the combination of a simple and compatible reaction tube platform with label free silicon-on-insulator (SOI) photonic biosensors, where the flow is through the sensor chip as opposed to over the chip as in more conventional approaches. This device allows real time detection and analysis. Its great flexibility and small footprint make it ideal for an easy handling in any laboratory.},
  articleno    = {85980I},
  author       = {Lerma Arce, Cristina and Goes, Arne and Hallynck, Elewout and Dubruel, Peter and Komorowska, Katarzyna and Van Put, Steven and Bienstman, Peter},
  booktitle    = {Proceedings of SPIE},
  issn         = {0277-786X},
  keyword      = {photonic microring resonators,Silicon nanophotonic sensors,Silicon-on-Insulator (SOI),reaction tubes,Enzyme-linked immunosorbert assay (ELISA)},
  language     = {eng},
  location     = {San Francisco, California},
  pages        = {7},
  publisher    = {Spie},
  title        = {Silicon nanophotonic ring resonators sensors integrated in reaction tubes},
  url          = {http://dx.doi.org/10.1117/12.2003970},
  volume       = {8598},
  year         = {2013},
}

Chicago
Lerma Arce, Cristina, Arne Goes, Elewout Hallynck, Peter Dubruel, Katarzyna Komorowska, Steven Van Put, and Peter Bienstman. 2013. “Silicon Nanophotonic Ring Resonators Sensors Integrated in Reaction Tubes.” In Proceedings of SPIE. Vol. 8598. Spie.
APA
Lerma Arce, C., Goes, A., Hallynck, E., Dubruel, P., Komorowska, K., Van Put, S., & Bienstman, P. (2013). Silicon nanophotonic ring resonators sensors integrated in reaction tubes. Proceedings of SPIE (Vol. 8598). Presented at the Conference on Bioinspired, Biointegrated, Bioengineered Photonic Devices, Spie.
Vancouver
1.
Lerma Arce C, Goes A, Hallynck E, Dubruel P, Komorowska K, Van Put S, et al. Silicon nanophotonic ring resonators sensors integrated in reaction tubes. Proceedings of SPIE. Spie; 2013.
MLA
Lerma Arce, Cristina, Arne Goes, Elewout Hallynck, et al. “Silicon Nanophotonic Ring Resonators Sensors Integrated in Reaction Tubes.” Proceedings of SPIE. Vol. 8598. Spie, 2013. Print.