Direct synthesis and morphological characterization of gold-dendrimer nanocomposites prepared using PAMAM succinamic acid dendrimers : preliminary study of the calcification potential
- Author
- E Vasile, A Serafim, D Petre, Elena Diana Giol (UGent) , Peter Dubruel (UGent) , H Iovu and IC Stancu
- Organization
- Abstract
- Gold-dendrimer nanocomposites were obtained for the first time by a simple colloidal approach based on the use of polyamidoamine dendrimers with succinamic acid terminal groups and dodecanediamine core. Spherical and highly crystalline nanoparticles with dimensions between 3 nm and 60 nm, and size-polydispersity depending on the synthesis conditions, have been generated. The influence of the stoichiometric ratio and the structural and architectural features of the dendrimers on the properties of the nanocomposites has been described. The self-assembling behaviour of these materials produces gold-dendrimer nanostructured porous networks with variable density, porosity, and composition. The investigations of the reaction systems, by TEM, at two postsynthesis moments, allowed to preliminary establish the control over the properties of the nanocomposite products. Furthermore, this study allowed better understanding of the mechanism of nanocomposite generation. Impressively, in the early stages of the synthesis, the organization of gold inside the dendrimer molecules has been evidenced by micrographs. Growth and ripening mechanisms further lead to nanoparticles with typical characteristics. The potential of such nanocomposite particles to induce calcification when coating a polymer substrate was also investigated.
- Keywords
- STABILIZED GOLD, SIMULATED BODY-FLUID, BIOMIMETIC PROCESS, NANOPARTICLES, SILVER, SURFACE, SIZE, IMMOBILIZATION, BIOACTIVITY, TERMINATED POLY(AMIDOAMINE) DENDRIMER
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Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers Preliminary Study of the Calcification Potential.pdf
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-4206046
- MLA
- Vasile, E., et al. “Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers : Preliminary Study of the Calcification Potential.” SCIENTIFIC WORLD JOURNAL, 2014, doi:10.1155/2014/103462.
- APA
- Vasile, E., Serafim, A., Petre, D., Giol, E. D., Dubruel, P., Iovu, H., & Stancu, I. (2014). Direct synthesis and morphological characterization of gold-dendrimer nanocomposites prepared using PAMAM succinamic acid dendrimers : preliminary study of the calcification potential. SCIENTIFIC WORLD JOURNAL. https://doi.org/10.1155/2014/103462
- Chicago author-date
- Vasile, E, A Serafim, D Petre, Elena Diana Giol, Peter Dubruel, H Iovu, and IC Stancu. 2014. “Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers : Preliminary Study of the Calcification Potential.” SCIENTIFIC WORLD JOURNAL. https://doi.org/10.1155/2014/103462.
- Chicago author-date (all authors)
- Vasile, E, A Serafim, D Petre, Elena Diana Giol, Peter Dubruel, H Iovu, and IC Stancu. 2014. “Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers : Preliminary Study of the Calcification Potential.” SCIENTIFIC WORLD JOURNAL. doi:10.1155/2014/103462.
- Vancouver
- 1.Vasile E, Serafim A, Petre D, Giol ED, Dubruel P, Iovu H, et al. Direct synthesis and morphological characterization of gold-dendrimer nanocomposites prepared using PAMAM succinamic acid dendrimers : preliminary study of the calcification potential. SCIENTIFIC WORLD JOURNAL. 2014;
- IEEE
- [1]E. Vasile et al., “Direct synthesis and morphological characterization of gold-dendrimer nanocomposites prepared using PAMAM succinamic acid dendrimers : preliminary study of the calcification potential,” SCIENTIFIC WORLD JOURNAL, 2014.
@article{4206046, abstract = {{Gold-dendrimer nanocomposites were obtained for the first time by a simple colloidal approach based on the use of polyamidoamine dendrimers with succinamic acid terminal groups and dodecanediamine core. Spherical and highly crystalline nanoparticles with dimensions between 3 nm and 60 nm, and size-polydispersity depending on the synthesis conditions, have been generated. The influence of the stoichiometric ratio and the structural and architectural features of the dendrimers on the properties of the nanocomposites has been described. The self-assembling behaviour of these materials produces gold-dendrimer nanostructured porous networks with variable density, porosity, and composition. The investigations of the reaction systems, by TEM, at two postsynthesis moments, allowed to preliminary establish the control over the properties of the nanocomposite products. Furthermore, this study allowed better understanding of the mechanism of nanocomposite generation. Impressively, in the early stages of the synthesis, the organization of gold inside the dendrimer molecules has been evidenced by micrographs. Growth and ripening mechanisms further lead to nanoparticles with typical characteristics. The potential of such nanocomposite particles to induce calcification when coating a polymer substrate was also investigated.}}, articleno = {{103462}}, author = {{Vasile, E and Serafim, A and Petre, D and Giol, Elena Diana and Dubruel, Peter and Iovu, H and Stancu, IC}}, issn = {{1537-744X}}, journal = {{SCIENTIFIC WORLD JOURNAL}}, keywords = {{STABILIZED GOLD,SIMULATED BODY-FLUID,BIOMIMETIC PROCESS,NANOPARTICLES,SILVER,SURFACE,SIZE,IMMOBILIZATION,BIOACTIVITY,TERMINATED POLY(AMIDOAMINE) DENDRIMER}}, language = {{eng}}, pages = {{15}}, title = {{Direct synthesis and morphological characterization of gold-dendrimer nanocomposites prepared using PAMAM succinamic acid dendrimers : preliminary study of the calcification potential}}, url = {{http://doi.org/10.1155/2014/103462}}, year = {{2014}}, }
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