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Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice

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Abstract
We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.
Keywords
Sputum, Bronchoscopy, YIELD, SPUTUM, Tuberculosis, pulmonary diagnosis

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Citation

Please use this url to cite or link to this publication:

Chicago
Soto Tarazona, Alonso Ricardo, Daniela Salazar, Vilma Acurio, Patricia Segura, and Patrick Van Der Stuyft. 2012. “Evaluation of the Diagnostic Utility of Fiberoptic Bronchoscopy for Smear-negative Pulmonary Tuberculosis in Routine Clinical Practice.” Jornal Brasileiro De Pneumologia 38 (6): 757–760.
APA
Soto Tarazona, A. R., Salazar, D., Acurio, V., Segura, P., & Van Der Stuyft, P. (2012). Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice. JORNAL BRASILEIRO DE PNEUMOLOGIA, 38(6), 757–760.
Vancouver
1.
Soto Tarazona AR, Salazar D, Acurio V, Segura P, Van Der Stuyft P. Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice. JORNAL BRASILEIRO DE PNEUMOLOGIA. 2012;38(6):757–60.
MLA
Soto Tarazona, Alonso Ricardo et al. “Evaluation of the Diagnostic Utility of Fiberoptic Bronchoscopy for Smear-negative Pulmonary Tuberculosis in Routine Clinical Practice.” JORNAL BRASILEIRO DE PNEUMOLOGIA 38.6 (2012): 757–760. Print.
@article{4126621,
  abstract     = {We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.},
  author       = {Soto Tarazona, Alonso Ricardo and Salazar, Daniela and Acurio, Vilma and Segura, Patricia and Van Der Stuyft, Patrick},
  issn         = {1806-3713},
  journal      = {JORNAL BRASILEIRO DE PNEUMOLOGIA},
  keywords     = {Sputum,Bronchoscopy,YIELD,SPUTUM,Tuberculosis,pulmonary diagnosis},
  language     = {eng},
  number       = {6},
  pages        = {757--760},
  title        = {Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice},
  url          = {http://www.jornaldepneumologia.com.br/detalhe_artigo.asp?id=1766},
  volume       = {38},
  year         = {2012},
}

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