A protein phosphatase 2A complex spatially controls plant cell division
- Author
- Lara Spinner, Astrid Gadeyne (UGent) , Katia Belcram, Magali Goussot, Michael Moison, Yann Duroc, Dominique Eeckhout (UGent) , Nancy De Winne (UGent) , Estelle Schaefer, Eveline Van De Slijke (UGent) , Geert Persiau (UGent) , Erwin Witters, Kris Gevaert (UGent) , Geert De Jaeger (UGent) , David Bouchez, Daniël Van Damme (UGent) and Martine Pastuglia
- Organization
- Abstract
- In the absence of cell migration, the orientation of cell divisions is crucial for body plan determination in plants. The position of the division plane in plant cells is set up premitotically via a transient cytoskeletal array, the preprophase band, which precisely delineates the cortical plane of division. Here we describe a protein complex that targets protein phosphatase 2A activity to microtubules, regulating the transition from the interphase to the premitotic microtubule array. This complex, which comprises TONNEAU1 and a PP2A heterotrimeric holoenzyme with FASS as regulatory subunit, is recruited to the cytoskeleton via the TONNEAU1-recruiting motif family of proteins. Despite the acentrosomal nature of plant cells, all members of this complex share similarity with animal centrosomal proteins involved in ciliary and centriolar/centrosomal functions, revealing an evolutionary link between the cortical cytoskeleton of plant cells and microtubule organizers in other eukaryotes.
- Keywords
- MICROTUBULE ORGANIZATION, GAMMA-TUBULIN, REGULATORY SUBUNIT, ARABIDOPSIS-THALIANA, PREPROPHASE BAND FORMATION, TANDEM AFFINITY PURIFICATION, CORTICAL ARRAY ORGANIZATION, LAND PLANTS, LOCALIZATION, REVEALS
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-4110253
- MLA
- Spinner, Lara, et al. “A Protein Phosphatase 2A Complex Spatially Controls Plant Cell Division.” NATURE COMMUNICATIONS, vol. 4, 2013, doi:10.1038/ncomms2831.
- APA
- Spinner, L., Gadeyne, A., Belcram, K., Goussot, M., Moison, M., Duroc, Y., … Pastuglia, M. (2013). A protein phosphatase 2A complex spatially controls plant cell division. NATURE COMMUNICATIONS, 4. https://doi.org/10.1038/ncomms2831
- Chicago author-date
- Spinner, Lara, Astrid Gadeyne, Katia Belcram, Magali Goussot, Michael Moison, Yann Duroc, Dominique Eeckhout, et al. 2013. “A Protein Phosphatase 2A Complex Spatially Controls Plant Cell Division.” NATURE COMMUNICATIONS 4. https://doi.org/10.1038/ncomms2831.
- Chicago author-date (all authors)
- Spinner, Lara, Astrid Gadeyne, Katia Belcram, Magali Goussot, Michael Moison, Yann Duroc, Dominique Eeckhout, Nancy De Winne, Estelle Schaefer, Eveline Van De Slijke, Geert Persiau, Erwin Witters, Kris Gevaert, Geert De Jaeger, David Bouchez, Daniël Van Damme, and Martine Pastuglia. 2013. “A Protein Phosphatase 2A Complex Spatially Controls Plant Cell Division.” NATURE COMMUNICATIONS 4. doi:10.1038/ncomms2831.
- Vancouver
- 1.Spinner L, Gadeyne A, Belcram K, Goussot M, Moison M, Duroc Y, et al. A protein phosphatase 2A complex spatially controls plant cell division. NATURE COMMUNICATIONS. 2013;4.
- IEEE
- [1]L. Spinner et al., “A protein phosphatase 2A complex spatially controls plant cell division,” NATURE COMMUNICATIONS, vol. 4, 2013.
@article{4110253, abstract = {{In the absence of cell migration, the orientation of cell divisions is crucial for body plan determination in plants. The position of the division plane in plant cells is set up premitotically via a transient cytoskeletal array, the preprophase band, which precisely delineates the cortical plane of division. Here we describe a protein complex that targets protein phosphatase 2A activity to microtubules, regulating the transition from the interphase to the premitotic microtubule array. This complex, which comprises TONNEAU1 and a PP2A heterotrimeric holoenzyme with FASS as regulatory subunit, is recruited to the cytoskeleton via the TONNEAU1-recruiting motif family of proteins. Despite the acentrosomal nature of plant cells, all members of this complex share similarity with animal centrosomal proteins involved in ciliary and centriolar/centrosomal functions, revealing an evolutionary link between the cortical cytoskeleton of plant cells and microtubule organizers in other eukaryotes.}}, articleno = {{1863}}, author = {{Spinner, Lara and Gadeyne, Astrid and Belcram, Katia and Goussot, Magali and Moison, Michael and Duroc, Yann and Eeckhout, Dominique and De Winne, Nancy and Schaefer, Estelle and Van De Slijke, Eveline and Persiau, Geert and Witters, Erwin and Gevaert, Kris and De Jaeger, Geert and Bouchez, David and Van Damme, Daniël and Pastuglia, Martine}}, issn = {{2041-1723}}, journal = {{NATURE COMMUNICATIONS}}, keywords = {{MICROTUBULE ORGANIZATION,GAMMA-TUBULIN,REGULATORY SUBUNIT,ARABIDOPSIS-THALIANA,PREPROPHASE BAND FORMATION,TANDEM AFFINITY PURIFICATION,CORTICAL ARRAY ORGANIZATION,LAND PLANTS,LOCALIZATION,REVEALS}}, language = {{eng}}, pages = {{13}}, title = {{A protein phosphatase 2A complex spatially controls plant cell division}}, url = {{http://doi.org/10.1038/ncomms2831}}, volume = {{4}}, year = {{2013}}, }
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