Advanced search
1 file | 1.95 MB Add to list

Red blood cells and polyelectrolyte multilayer capsules: natural carriers versus polymer-based drug delivery vehicles

Author
Organization
Project
Center for nano- and biophotonics (NB-Photonics)
Abstract
Introduction: Red blood cells (RBCs) and lipid-based carriers on the one hand and polymeric capsules on the other hand represent two of the most widely used carriers in drug delivery. Each class of these carriers has its own set of properties, specificity and advantages. Thorough comparative studies of such systems are reported here for the first time. Areas covered: In this review, RBCs are described in comparison with synthetic polymeric drug delivery vehicles using polyelectrolyte multilayer capsules as an example. Lipid-based composition of the shell in the former case is particularly attractive due to their inherent biocompatibility and flexibility of the carriers. On the other hand, synthetic approaches to fabrication of polyelectrolyte multilayer capsules permit manipulation of the permeability of their shell as well as tuning their composition, mechanical properties, release methods and targeting. Expert Opinion: In conclusion, properties of RBCs and polyelectrolyte multilayer capsules are reported here highlighting similarities and differences in their preparation and applications. In addition, their advantages and disadvantages are discussed.
Keywords
multicompartments, layer-by-layer, multilayer capsules, natural carriers, polymer-based vehicles, red blood cells, ENCAPSULATED MATERIALS, MECHANICAL-PROPERTIES, PROTEIN DELIVERY, MICROCAPSULES, RELEASE, NANOPARTICLES, ERYTHROCYTES, LIPOSOMES, LAYER, MICROCONTAINERS

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 1.95 MB

Citation

Please use this url to cite or link to this publication:

MLA
Kolesnikova, Tatiana A, Andre Skirtach, and Helmuth Möhwald. “Red Blood Cells and Polyelectrolyte Multilayer Capsules: Natural Carriers Versus Polymer-based Drug Delivery Vehicles.” EXPERT OPINION ON DRUG DELIVERY 10.1 (2013): 47–58. Print.
APA
Kolesnikova, T. A., Skirtach, A., & Möhwald, H. (2013). Red blood cells and polyelectrolyte multilayer capsules: natural carriers versus polymer-based drug delivery vehicles. EXPERT OPINION ON DRUG DELIVERY, 10(1), 47–58.
Chicago author-date
Kolesnikova, Tatiana A, Andre Skirtach, and Helmuth Möhwald. 2013. “Red Blood Cells and Polyelectrolyte Multilayer Capsules: Natural Carriers Versus Polymer-based Drug Delivery Vehicles.” Expert Opinion on Drug Delivery 10 (1): 47–58.
Chicago author-date (all authors)
Kolesnikova, Tatiana A, Andre Skirtach, and Helmuth Möhwald. 2013. “Red Blood Cells and Polyelectrolyte Multilayer Capsules: Natural Carriers Versus Polymer-based Drug Delivery Vehicles.” Expert Opinion on Drug Delivery 10 (1): 47–58.
Vancouver
1.
Kolesnikova TA, Skirtach A, Möhwald H. Red blood cells and polyelectrolyte multilayer capsules: natural carriers versus polymer-based drug delivery vehicles. EXPERT OPINION ON DRUG DELIVERY. 2013;10(1):47–58.
IEEE
[1]
T. A. Kolesnikova, A. Skirtach, and H. Möhwald, “Red blood cells and polyelectrolyte multilayer capsules: natural carriers versus polymer-based drug delivery vehicles,” EXPERT OPINION ON DRUG DELIVERY, vol. 10, no. 1, pp. 47–58, 2013.
@article{4080677,
  abstract     = {Introduction: Red blood cells (RBCs) and lipid-based carriers on the one hand and polymeric capsules on the other hand represent two of the most widely used carriers in drug delivery. Each class of these carriers has its own set of properties, specificity and advantages. Thorough comparative studies of such systems are reported here for the first time.
Areas covered: In this review, RBCs are described in comparison with synthetic polymeric drug delivery vehicles using polyelectrolyte multilayer capsules as an example. Lipid-based composition of the shell in the former case is particularly attractive due to their inherent biocompatibility and flexibility of the carriers. On the other hand, synthetic approaches to fabrication of polyelectrolyte multilayer capsules permit manipulation of the permeability of their shell as well as tuning their composition, mechanical properties, release methods and targeting.
Expert Opinion: In conclusion, properties of RBCs and polyelectrolyte multilayer capsules are reported here highlighting similarities and differences in their preparation and applications. In addition, their advantages and disadvantages are discussed.},
  author       = {Kolesnikova, Tatiana A and Skirtach, Andre and Möhwald, Helmuth},
  issn         = {1742-5247},
  journal      = {EXPERT OPINION ON DRUG DELIVERY},
  keywords     = {multicompartments,layer-by-layer,multilayer capsules,natural carriers,polymer-based vehicles,red blood cells,ENCAPSULATED MATERIALS,MECHANICAL-PROPERTIES,PROTEIN DELIVERY,MICROCAPSULES,RELEASE,NANOPARTICLES,ERYTHROCYTES,LIPOSOMES,LAYER,MICROCONTAINERS},
  language     = {eng},
  number       = {1},
  pages        = {47--58},
  title        = {Red blood cells and polyelectrolyte multilayer capsules: natural carriers versus polymer-based drug delivery vehicles},
  url          = {http://dx.doi.org/10.1517/17425247.2013.730516},
  volume       = {10},
  year         = {2013},
}

Altmetric
View in Altmetric
Web of Science
Times cited: