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Inhaled nitric oxide selectively reverses the hypoxic pulmonary vasoconstrictor response in calves

Author
Organization
Abstract
The effect of inhaling nitric oxide on the hypoxic pulmonary vasoconstrictor response in calves was evaluated. In five healthy, anaesthetised Friesian Holstein calves alveolar hypoxia was induced by means of the inhalation of a gas mixture with an inspiratory oxygen fraction of 14 - 18 %. This alveolar hypoxia resulted in a pronounced pulmonary hypertension. The inhalation of 20 and 40 ppm of nitric oxide induced a significant fall of the hypoxic pulmonary hypertension. A concentration of 40 ppm of nitric oxide was needed to fully abolish the induced pulmonary hypertension. The inhalation of nitric oxide had no effect on the systemic arterial pressure nor on the systemic vascular resistance. It was concluded that the inhalation of nitric oxide resulted in a selective pulmonary vasodilatation during alveolar hypoxia in calves.
Keywords
hypoxic pulmonary hypertension, nitric oxide, calf

Citation

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MLA
Sustronck, Bart, Gunther van Loon, Frank Gasthuys, et al. “Inhaled Nitric Oxide Selectively Reverses the Hypoxic Pulmonary Vasoconstrictor Response in Calves.” World Association for Buiatrics : XIX Congress, Vols 1-3. Frampton-on-Severn, UK: British Cattle Veterinary Association, 1996. 644–647. Print.
APA
Sustronck, B., van Loon, G., Gasthuys, F., Foubert, L., Deprez, P., & Muylle, E. (1996). Inhaled nitric oxide selectively reverses the hypoxic pulmonary vasoconstrictor response in calves. World Association for Buiatrics : XIX congress, vols 1-3 (pp. 644–647). Presented at the 19th World Buiatrics Congress, Frampton-on-Severn, UK: British Cattle Veterinary Association.
Chicago author-date
Sustronck, Bart, Gunther van Loon, Frank Gasthuys, L Foubert, Piet Deprez, and Etienne Muylle. 1996. “Inhaled Nitric Oxide Selectively Reverses the Hypoxic Pulmonary Vasoconstrictor Response in Calves.” In World Association for Buiatrics : XIX Congress, Vols 1-3, 644–647. Frampton-on-Severn, UK: British Cattle Veterinary Association.
Chicago author-date (all authors)
Sustronck, Bart, Gunther van Loon, Frank Gasthuys, L Foubert, Piet Deprez, and Etienne Muylle. 1996. “Inhaled Nitric Oxide Selectively Reverses the Hypoxic Pulmonary Vasoconstrictor Response in Calves.” In World Association for Buiatrics : XIX Congress, Vols 1-3, 644–647. Frampton-on-Severn, UK: British Cattle Veterinary Association.
Vancouver
1.
Sustronck B, van Loon G, Gasthuys F, Foubert L, Deprez P, Muylle E. Inhaled nitric oxide selectively reverses the hypoxic pulmonary vasoconstrictor response in calves. World Association for Buiatrics : XIX congress, vols 1-3. Frampton-on-Severn, UK: British Cattle Veterinary Association; 1996. p. 644–7.
IEEE
[1]
B. Sustronck, G. van Loon, F. Gasthuys, L. Foubert, P. Deprez, and E. Muylle, “Inhaled nitric oxide selectively reverses the hypoxic pulmonary vasoconstrictor response in calves,” in World Association for Buiatrics : XIX congress, vols 1-3, Edinburgh, Scotland, UK, 1996, pp. 644–647.
@inproceedings{398683,
  abstract     = {The effect of inhaling nitric oxide on the hypoxic pulmonary vasoconstrictor response in calves was evaluated. In five healthy, anaesthetised Friesian Holstein calves alveolar hypoxia was induced by means of the inhalation of a gas mixture with an inspiratory oxygen fraction of 14 - 18 %. This alveolar hypoxia resulted in a pronounced pulmonary hypertension. The inhalation of 20 and 40 ppm of nitric oxide induced a significant fall of the hypoxic pulmonary hypertension. A concentration of 40 ppm of nitric oxide was needed to fully abolish the induced pulmonary hypertension. The inhalation of nitric oxide had no effect on the systemic arterial pressure nor on the systemic vascular resistance. It was concluded that the inhalation of nitric oxide resulted in a selective pulmonary vasodilatation during alveolar hypoxia in calves.},
  author       = {Sustronck, Bart and van Loon, Gunther and Gasthuys, Frank and Foubert, L and Deprez, Piet and Muylle, Etienne},
  booktitle    = {World Association for Buiatrics : XIX congress, vols 1-3},
  keywords     = {hypoxic pulmonary hypertension,nitric oxide,calf},
  language     = {eng},
  location     = {Edinburgh, Scotland, UK},
  pages        = {644--647},
  publisher    = {British Cattle Veterinary Association},
  title        = {Inhaled nitric oxide selectively reverses the hypoxic pulmonary vasoconstrictor response in calves},
  year         = {1996},
}