Ghent University Academic Bibliography

Advanced

Use of [I-121]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma

Peremans, Kathelijne UGent, Kersemans, Veerle, Liuti, Tiziana, Vandermeulen, Eva UGent, Cornelissen, Bart, Gielen, Ingrid UGent, De Spiegeleer, Bart UGent, MERTENS, J, Burvenich, Christian UGent and Slegers, Guido UGent (2007) VETERINARY RADIOLOGY & ULTRASOUND. 48(5). p.471-474
abstract
[I-123]-iodo-L-phenylalanine was successfully evaluated for gamma camera imaging in vivo in tumor-bearing athymic mice and in humans with brain tumors. Here, we report the use of this tracer in two dogs with synovial cell sarcoma of the tarsus. [I-123]-iodo-L-phenylalanine was quantitatively prepared as a kit formulation using the Cu1+-assisted nucleophilic exchange. Rapid [I-123]-2-iodo-L-phenylalanine tumor accumulation was observed with good tumor to background contrast and rapid clearance in these two dogs. This radiopharmaceutical is a promising alternative tumor tracer to overcome the known limitations of F-18-fluorodeoxyglucose and, when labelled with radioiodine-131, has the potential to be used for therapeutic purposes.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
TRACER, DIAGNOSIS, THERAPY, PHEOCHROMOCYTOMA, TRANSPORT, DOSIMETRY, ONCOLOGY, [I-123]-2-iodo-L-phenylaianine, dogs, gamma camera imaging, synovial carcinoma, tumor diagnosticum, ATHYMIC MOUSE MODEL, AMINO-ACID, SPECT
journal title
VETERINARY RADIOLOGY & ULTRASOUND
Vet. Radiol. Ultrasound
volume
48
issue
5
pages
471-474 pages
publisher
BLACKWELL PUBLISHING
Web of Science type
Article
Web of Science id
000249288600015
JCR category
VETERINARY SCIENCES
JCR impact factor
1.053 (2007)
JCR rank
39/122 (2007)
JCR quartile
2 (2007)
ISSN
1058-8183
DOI
10.1111/j.1740-8261.2007.00281.x
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
382561
handle
http://hdl.handle.net/1854/LU-382561
date created
2007-11-24 13:41:00
date last changed
2016-12-19 15:44:28
@article{382561,
  abstract     = {[I-123]-iodo-L-phenylalanine was successfully evaluated for gamma camera imaging in vivo in tumor-bearing athymic mice and in humans with brain tumors. Here, we report the use of this tracer in two dogs with synovial cell sarcoma of the tarsus. [I-123]-iodo-L-phenylalanine was quantitatively prepared as a kit formulation using the Cu1+-assisted nucleophilic exchange. Rapid [I-123]-2-iodo-L-phenylalanine tumor accumulation was observed with good tumor to background contrast and rapid clearance in these two dogs. This radiopharmaceutical is a promising alternative tumor tracer to overcome the known limitations of F-18-fluorodeoxyglucose and, when labelled with radioiodine-131, has the potential to be used for therapeutic purposes.},
  author       = {Peremans, Kathelijne and Kersemans, Veerle and Liuti, Tiziana and Vandermeulen, Eva and Cornelissen, Bart and Gielen, Ingrid and De Spiegeleer, Bart and MERTENS, J and Burvenich, Christian and Slegers, Guido},
  issn         = {1058-8183},
  journal      = {VETERINARY RADIOLOGY \& ULTRASOUND},
  keyword      = {TRACER,DIAGNOSIS,THERAPY,PHEOCHROMOCYTOMA,TRANSPORT,DOSIMETRY,ONCOLOGY,[I-123]-2-iodo-L-phenylaianine,dogs,gamma camera imaging,synovial carcinoma,tumor diagnosticum,ATHYMIC MOUSE MODEL,AMINO-ACID,SPECT},
  language     = {eng},
  number       = {5},
  pages        = {471--474},
  publisher    = {BLACKWELL PUBLISHING},
  title        = {Use of [I-121]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma},
  url          = {http://dx.doi.org/10.1111/j.1740-8261.2007.00281.x},
  volume       = {48},
  year         = {2007},
}

Chicago
Peremans, Kathelijne, Veerle Kersemans, Tiziana Liuti, Eva Vandermeulen, Bart Cornelissen, Ingrid Gielen, Bart De Spiegeleer, J MERTENS, Christian Burvenich, and Guido Slegers. 2007. “Use of [I-121]-2-iodo-L-phenylalanine as a Tumor Imaging Agent in Two Dogs with Synovial Cell Sarcoma.” Veterinary Radiology & Ultrasound 48 (5): 471–474.
APA
Peremans, K., Kersemans, V., Liuti, T., Vandermeulen, E., Cornelissen, B., Gielen, I., De Spiegeleer, B., et al. (2007). Use of [I-121]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma. VETERINARY RADIOLOGY & ULTRASOUND, 48(5), 471–474.
Vancouver
1.
Peremans K, Kersemans V, Liuti T, Vandermeulen E, Cornelissen B, Gielen I, et al. Use of [I-121]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma. VETERINARY RADIOLOGY & ULTRASOUND. BLACKWELL PUBLISHING; 2007;48(5):471–4.
MLA
Peremans, Kathelijne, Veerle Kersemans, Tiziana Liuti, et al. “Use of [I-121]-2-iodo-L-phenylalanine as a Tumor Imaging Agent in Two Dogs with Synovial Cell Sarcoma.” VETERINARY RADIOLOGY & ULTRASOUND 48.5 (2007): 471–474. Print.