The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders
- Author
- Karen van der Meulen (UGent) , Annick Gryspeerdt (UGent) , Annelies Vandekerckhove (UGent) , Barbara Garré (UGent) and Hans Nauwynck (UGent)
- Organization
- Abstract
- Equine herpesvirus (EHV) 1 is an important pathogen of horses. Upon infection, the virus replicates in the upper respiratory tract. Then it spreads to internal organs via a cell-associated viremia. Local replication in internal organs may result in abortion and nervous system disorders. The currently designed vaccines are not able to induce significant protection against EHV1-induced viremia. However, several vaccines are able to induce a significant level of protection against either abortion or nervous system disorders. Which immune responses correlate with this protection is so far unknown. Besides vaccination, management will remain a crucial factor in the prevention of EHV1-induced clinical signs. Management measures include the vaccination of all horses on the premises to reduce infection pressure; the separate housing of young horses, adult horses and pregnant mares; strict hygiene measures and strict control of contact with horses from outside the premises. If, despite vaccination and thorough management, an outbreak of EHV1-induced disease occurs, treatment with antiviral agents may be useful.
- Keywords
- PATHOGEN-FREE FOALS, ENDOTHELIAL-CELL INFECTION, GLYCOPROTEIN-D, MURINE MODEL, EXPERIMENTAL CHALLENGE, RESPIRATORY-TRACT, DELETION MUTANT, TYPE-1 EHV-1, YOUNG HORSES, ADULT HORSES
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The pro tec tive prop er ties of vac ci na tion against equine herpesvirus 1-in duced viremia abor tion and ner vous sys tem dis or ders.pdf
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-378958
- MLA
- van der Meulen, Karen, et al. “The Protective Properties of Vaccination against Equine Herpesvirus 1-Induced Viremia, Abortion and Nervous System Disorders.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, vol. 76, no. 3, 2007, pp. 186–94.
- APA
- van der Meulen, K., Gryspeerdt, A., Vandekerckhove, A., Garré, B., & Nauwynck, H. (2007). The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, 76(3), 186–194.
- Chicago author-date
- Meulen, Karen van der, Annick Gryspeerdt, Annelies Vandekerckhove, Barbara Garré, and Hans Nauwynck. 2007. “The Protective Properties of Vaccination against Equine Herpesvirus 1-Induced Viremia, Abortion and Nervous System Disorders.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT 76 (3): 186–94.
- Chicago author-date (all authors)
- van der Meulen, Karen, Annick Gryspeerdt, Annelies Vandekerckhove, Barbara Garré, and Hans Nauwynck. 2007. “The Protective Properties of Vaccination against Equine Herpesvirus 1-Induced Viremia, Abortion and Nervous System Disorders.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT 76 (3): 186–194.
- Vancouver
- 1.van der Meulen K, Gryspeerdt A, Vandekerckhove A, Garré B, Nauwynck H. The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT. 2007;76(3):186–94.
- IEEE
- [1]K. van der Meulen, A. Gryspeerdt, A. Vandekerckhove, B. Garré, and H. Nauwynck, “The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders,” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, vol. 76, no. 3, pp. 186–194, 2007.
@article{378958, abstract = {{Equine herpesvirus (EHV) 1 is an important pathogen of horses. Upon infection, the virus replicates in the upper respiratory tract. Then it spreads to internal organs via a cell-associated viremia. Local replication in internal organs may result in abortion and nervous system disorders. The currently designed vaccines are not able to induce significant protection against EHV1-induced viremia. However, several vaccines are able to induce a significant level of protection against either abortion or nervous system disorders. Which immune responses correlate with this protection is so far unknown. Besides vaccination, management will remain a crucial factor in the prevention of EHV1-induced clinical signs. Management measures include the vaccination of all horses on the premises to reduce infection pressure; the separate housing of young horses, adult horses and pregnant mares; strict hygiene measures and strict control of contact with horses from outside the premises. If, despite vaccination and thorough management, an outbreak of EHV1-induced disease occurs, treatment with antiviral agents may be useful.}}, author = {{van der Meulen, Karen and Gryspeerdt, Annick and Vandekerckhove, Annelies and Garré, Barbara and Nauwynck, Hans}}, issn = {{0303-9021}}, journal = {{VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT}}, keywords = {{PATHOGEN-FREE FOALS,ENDOTHELIAL-CELL INFECTION,GLYCOPROTEIN-D,MURINE MODEL,EXPERIMENTAL CHALLENGE,RESPIRATORY-TRACT,DELETION MUTANT,TYPE-1 EHV-1,YOUNG HORSES,ADULT HORSES}}, language = {{dut}}, number = {{3}}, pages = {{186--194}}, title = {{The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders}}, url = {{http://vdt.ugent.be/code/showupload.php?id=292}}, volume = {{76}}, year = {{2007}}, }