Advanced search
1 file | 218.33 KB

The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders

Author
Organization
Abstract
Equine herpesvirus (EHV) 1 is an important pathogen of horses. Upon infection, the virus replicates in the upper respiratory tract. Then it spreads to internal organs via a cell-associated viremia. Local replication in internal organs may result in abortion and nervous system disorders. The currently designed vaccines are not able to induce significant protection against EHV1-induced viremia. However, several vaccines are able to induce a significant level of protection against either abortion or nervous system disorders. Which immune responses correlate with this protection is so far unknown. Besides vaccination, management will remain a crucial factor in the prevention of EHV1-induced clinical signs. Management measures include the vaccination of all horses on the premises to reduce infection pressure; the separate housing of young horses, adult horses and pregnant mares; strict hygiene measures and strict control of contact with horses from outside the premises. If, despite vaccination and thorough management, an outbreak of EHV1-induced disease occurs, treatment with antiviral agents may be useful.
Keywords
PATHOGEN-FREE FOALS, ENDOTHELIAL-CELL INFECTION, GLYCOPROTEIN-D, MURINE MODEL, EXPERIMENTAL CHALLENGE, RESPIRATORY-TRACT, DELETION MUTANT, TYPE-1 EHV-1, YOUNG HORSES, ADULT HORSES

Downloads

  • The pro tec tive prop er ties of vac ci na tion against equine herpesvirus 1-in duced viremia abor tion and ner vous sys tem dis or ders.pdf
    • full text
    • |
    • open access
    • |
    • PDF
    • |
    • 218.33 KB

Citation

Please use this url to cite or link to this publication:

Chicago
van der Meulen, Karen, Annick Gryspeerdt, Annelies Vandekerckhove, Barbara Garré, and Hans Nauwynck. 2007. “The Protective Properties of Vaccination Against Equine Herpesvirus 1-induced Viremia, Abortion and Nervous System Disorders.” Vlaams Diergeneeskundig Tijdschrift 76 (3): 186–194.
APA
van der Meulen, Karen, Gryspeerdt, A., Vandekerckhove, A., Garré, B., & Nauwynck, H. (2007). The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, 76(3), 186–194.
Vancouver
1.
van der Meulen K, Gryspeerdt A, Vandekerckhove A, Garré B, Nauwynck H. The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT. 2007;76(3):186–94.
MLA
van der Meulen, Karen, Annick Gryspeerdt, Annelies Vandekerckhove, et al. “The Protective Properties of Vaccination Against Equine Herpesvirus 1-induced Viremia, Abortion and Nervous System Disorders.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT 76.3 (2007): 186–194. Print.
@article{378958,
  abstract     = {Equine herpesvirus (EHV) 1 is an important pathogen of horses. Upon infection, the virus replicates in the upper respiratory tract. Then it spreads to internal organs via a cell-associated viremia. Local replication in internal organs may result in abortion and nervous system disorders. The currently designed vaccines are not able to induce significant protection against EHV1-induced viremia. However, several vaccines are able to induce a significant level of protection against either abortion or nervous system disorders. Which immune responses correlate with this protection is so far unknown. Besides vaccination, management will remain a crucial factor in the prevention of EHV1-induced clinical signs. Management measures include the vaccination of all horses on the premises to reduce infection pressure; the separate housing of young horses, adult horses and pregnant mares; strict hygiene measures and strict control of contact with horses from outside the premises. If, despite vaccination and thorough management, an outbreak of EHV1-induced disease occurs, treatment with antiviral agents may be useful.},
  author       = {van der Meulen, Karen and Gryspeerdt, Annick and Vandekerckhove, Annelies and Garr{\'e}, Barbara and Nauwynck, Hans},
  issn         = {0303-9021},
  journal      = {VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT},
  language     = {dut},
  number       = {3},
  pages        = {186--194},
  title        = {The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders},
  url          = {http://vdt.ugent.be/code/showupload.php?id=292},
  volume       = {76},
  year         = {2007},
}

Web of Science
Times cited: