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Cyclin-dependent kinase inhibitors in yeast, animals, and plants: a functional comparison

Annelies De Clercq UGent and Dirk Inzé UGent (2006) CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. 41(5). p.293-313
abstract
The cell cycle is remarkably conserved in yeast, animals, and plants and is controlled by cyclin-dependent kinases (CDKs). CDK activity can be inhibited by binding of CDK inhibitory proteins, designated CKIs. Numerous studies show that CKIs are essential in orchestrating eukaryotic cell proliferation and differentiation. In yeast, animals, and plants, CKIs act as regulators of the G1 checkpoint in response to environmental and developmental cues and assist during mitotic cell cycles by inhibiting CDK activity required to arrest mitosis. Furthermore, CKIs play an important role in regulating cell cycle exit that precedes differentiation and in promoting differentiation in cooperation with transcription factors. Moreover, CKIs are essential to control CDK activity in endocycling cells. So, in yeast, animals, and plants, CKIs share many functional similarities, but their functions are adapted toward the specific needs of the eukaryote.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
CAENORHABDITIS-ELEGANS, ARABIDOPSIS-THALIANA, PROTEIN-KINASE, G1 CYCLIN, SACCHAROMYCES-CEREVISIAE, CDK-INHIBITOR, CELL NUCLEAR ANTIGEN, TUMOR-SUPPRESSOR GENE, B-TYPE CYCLIN, GENOME-WIDE ANALYSIS, differentiation, proliferation, checkpoint, CKI, cell cycle
journal title
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
Crit. Rev. Biochem. Mol. Biol.
volume
41
issue
5
pages
293 - 313
Web of Science type
Review
Web of Science id
000239768300002
JCR category
BIOCHEMISTRY & MOLECULAR BIOLOGY
JCR impact factor
9.393 (2006)
JCR rank
18/259 (2006)
JCR quartile
1 (2006)
ISSN
1040-9238
DOI
10.1080/10409230600856685
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
371526
handle
http://hdl.handle.net/1854/LU-371526
date created
2007-07-03 15:50:00
date last changed
2013-10-18 14:58:08
@article{371526,
  abstract     = {The cell cycle is remarkably conserved in yeast, animals, and plants and is controlled by cyclin-dependent kinases (CDKs). CDK activity can be inhibited by binding of CDK inhibitory proteins, designated CKIs. Numerous studies show that CKIs are essential in orchestrating eukaryotic cell proliferation and differentiation. In yeast, animals, and plants, CKIs act as regulators of the G1 checkpoint in response to environmental and developmental cues and assist during mitotic cell cycles by inhibiting CDK activity required to arrest mitosis. Furthermore, CKIs play an important role in regulating cell cycle exit that precedes differentiation and in promoting differentiation in cooperation with transcription factors. Moreover, CKIs are essential to control CDK activity in endocycling cells. So, in yeast, animals, and plants, CKIs share many functional similarities, but their functions are adapted toward the specific needs of the eukaryote.},
  author       = {De Clercq, Annelies and Inz{\'e}, Dirk},
  issn         = {1040-9238},
  journal      = {CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY},
  keyword      = {CAENORHABDITIS-ELEGANS,ARABIDOPSIS-THALIANA,PROTEIN-KINASE,G1 CYCLIN,SACCHAROMYCES-CEREVISIAE,CDK-INHIBITOR,CELL NUCLEAR ANTIGEN,TUMOR-SUPPRESSOR GENE,B-TYPE CYCLIN,GENOME-WIDE ANALYSIS,differentiation,proliferation,checkpoint,CKI,cell cycle},
  language     = {eng},
  number       = {5},
  pages        = {293--313},
  title        = {Cyclin-dependent kinase inhibitors in yeast, animals, and plants: a functional comparison},
  url          = {http://dx.doi.org/10.1080/10409230600856685},
  volume       = {41},
  year         = {2006},
}
Chicago
De Clercq, Annelies, and Dirk Inzé. 2006. “Cyclin-dependent Kinase Inhibitors in Yeast, Animals, and Plants: a Functional Comparison.” Critical Reviews in Biochemistry and Molecular Biology 41 (5): 293–313.
APA
De Clercq, Annelies, & Inzé, D. (2006). Cyclin-dependent kinase inhibitors in yeast, animals, and plants: a functional comparison. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 41(5), 293–313.
Vancouver
1.
De Clercq A, Inzé D. Cyclin-dependent kinase inhibitors in yeast, animals, and plants: a functional comparison. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2006;41(5):293–313.
MLA
De Clercq, Annelies, and Dirk Inzé. “Cyclin-dependent Kinase Inhibitors in Yeast, Animals, and Plants: a Functional Comparison.” CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY 41.5 (2006): 293–313. Print.