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The Arabidopsis leaf as a model system for investigating the role of cell cycle regulation in organ growth

Gerrit Beemster UGent, Steven Vercruysse, Lieven De Veylder UGent, Martin Kuiper UGent and Dirk Inzé UGent (2006) JOURNAL OF PLANT RESEARCH. 119(1). p.43-50
abstract
The role of cell cycle regulation and cell division in plant growth and organ development is controversial. Some experimental data are most easily interpreted from the "cellular perspective" that cell division drives growth, whereas other observations are more consistent with the "organismal perspective" that cell division is merely a consequence of growth, and to a large extent facultative. Here we develop a model of cell cycle regulation in the context of leaf development based on literature, published kinematic analysis, flow-cytometric and transcriptomic data obtained from growing Arabidopsis leaves. We tested this model by comparing the in silico inhibition of the cell cycle progression with the experimental observations of transgenic plants overexpressing the cell cycle inhibitor Arath;KRP2. The model simulates the behaviour of proliferating cells quite well, but is inadequate in describing the effects on expanding cells. This may point to a difference in the nature of the expansion process during the proliferating and non-dividing phase of leaf development.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
TRANSCRIPTION FACTOR, TRANSITIONS, GENOME-WIDE ANALYSIS, modeling, leaf growth, endoreduplication, cell growth, Arabidopsis, cell division
journal title
JOURNAL OF PLANT RESEARCH
J. Plant Res.
volume
119
issue
1
pages
43 - 50
Web of Science type
Article
Web of Science id
000235407000007
JCR category
PLANT SCIENCES
JCR impact factor
1.225 (2006)
JCR rank
61/145 (2006)
JCR quartile
2 (2006)
ISSN
0918-9440
DOI
10.1007/s10265-005-0234-2
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
366835
handle
http://hdl.handle.net/1854/LU-366835
date created
2007-05-21 15:23:00
date last changed
2016-12-19 15:40:17
@article{366835,
  abstract     = {The role of cell cycle regulation and cell division in plant growth and organ development is controversial. Some experimental data are most easily interpreted from the {\textacutedbl}cellular perspective{\textacutedbl} that cell division drives growth, whereas other observations are more consistent with the {\textacutedbl}organismal perspective{\textacutedbl} that cell division is merely a consequence of growth, and to a large extent facultative. Here we develop a model of cell cycle regulation in the context of leaf development based on literature, published kinematic analysis, flow-cytometric and transcriptomic data obtained from growing Arabidopsis leaves. We tested this model by comparing the in silico inhibition of the cell cycle progression with the experimental observations of transgenic plants overexpressing the cell cycle inhibitor Arath;KRP2. The model simulates the behaviour of proliferating cells quite well, but is inadequate in describing the effects on expanding cells. This may point to a difference in the nature of the expansion process during the proliferating and non-dividing phase of leaf development.},
  author       = {Beemster, Gerrit and Vercruysse, Steven and De Veylder, Lieven and Kuiper, Martin and Inz{\'e}, Dirk},
  issn         = {0918-9440},
  journal      = {JOURNAL OF PLANT RESEARCH},
  keyword      = {TRANSCRIPTION FACTOR,TRANSITIONS,GENOME-WIDE ANALYSIS,modeling,leaf growth,endoreduplication,cell growth,Arabidopsis,cell division},
  language     = {eng},
  number       = {1},
  pages        = {43--50},
  title        = {The Arabidopsis leaf as a model system for investigating the role of cell cycle regulation in organ growth},
  url          = {http://dx.doi.org/10.1007/s10265-005-0234-2},
  volume       = {119},
  year         = {2006},
}

Chicago
Beemster, Gerrit, Steven Vercruysse, Lieven De Veylder, Martin Kuiper, and Dirk Inzé. 2006. “The Arabidopsis Leaf as a Model System for Investigating the Role of Cell Cycle Regulation in Organ Growth.” Journal of Plant Research 119 (1): 43–50.
APA
Beemster, G., Vercruysse, S., De Veylder, L., Kuiper, M., & Inzé, D. (2006). The Arabidopsis leaf as a model system for investigating the role of cell cycle regulation in organ growth. JOURNAL OF PLANT RESEARCH, 119(1), 43–50.
Vancouver
1.
Beemster G, Vercruysse S, De Veylder L, Kuiper M, Inzé D. The Arabidopsis leaf as a model system for investigating the role of cell cycle regulation in organ growth. JOURNAL OF PLANT RESEARCH. 2006;119(1):43–50.
MLA
Beemster, Gerrit, Steven Vercruysse, Lieven De Veylder, et al. “The Arabidopsis Leaf as a Model System for Investigating the Role of Cell Cycle Regulation in Organ Growth.” JOURNAL OF PLANT RESEARCH 119.1 (2006): 43–50. Print.