Ghent University Academic Bibliography

Advanced

A mutation of the mitochondrial ABC transporter Sta1 leads to dwarfism and chlorosis in the Arabidopsis mutant starik

Sergei Kushnir UGent, Elena Babiychuk UGent, Serguei Storojenko UGent, Mark W Davey UGent, Jutta Papenbrock, Riet De Rycke UGent, Gilbert Engler UGent, Udo W Stephan, Heike Lange, Gyula Kispal, et al. (2001) PLANT CELL. 13(1). p.89-100
abstract
A mutation in the Arabidopsis gene STARIK leads to dwarfism and chlorosis of plants with an altered morphology of leaf and cell nuclei. We show that the STARIK gene encodes the mitochondrial ABC transporter Stal that belongs to a subfamily of Arabidopsis half-ABC transporters. The severity of the starik phenotype is suppressed by the ectopic expression of the STA2 homolog; thus, Stal function is partially redundant, Stal supports the maturation of cytosolic Fe/S protein in Delta atm1 yeast, substituting for the ABC transporter Atm1p, Similar to Atm1p-deficient yeast, mitochondria of the starik mutant accumulated more nonheme, nonprotein iron than did wild-type organelles, We further show that plant mitochondria contain a putative L-cysteine desulfurase. Taken together, our results suggest that plant mitochondria possess an evolutionarily conserved Fe/S cluster biosynthesis pathway, which is linked to the intracellular iron homeostasis by the function of Atm1p-like ABC transporters.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
EXPRESSION, HIGHER-PLANTS, AMINO-ACID TRANSAMINASES, HOMOLOGS, PROTEIN, YEAST, GENE, THALIANA, SACCHAROMYCES-CEREVISIAE, IRON HOMEOSTASIS
journal title
PLANT CELL
Plant Cell
volume
13
issue
1
pages
89 - 100
Web of Science type
Article
Web of Science id
000167544800006
JCR category
PLANT SCIENCES
JCR impact factor
11.081 (2001)
JCR rank
2/134 (2001)
JCR quartile
1 (2001)
ISSN
1040-4651
DOI
10.1105/tpc.13.1.89
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
348417
handle
http://hdl.handle.net/1854/LU-348417
date created
2006-06-07 16:21:00
date last changed
2016-12-19 15:44:52
@article{348417,
  abstract     = {A mutation in the Arabidopsis gene STARIK leads to dwarfism and chlorosis of plants with an altered morphology of leaf and cell nuclei. We show that the STARIK gene encodes the mitochondrial ABC transporter Stal that belongs to a subfamily of Arabidopsis half-ABC transporters. The severity of the starik phenotype is suppressed by the ectopic expression of the STA2 homolog; thus, Stal function is partially redundant, Stal supports the maturation of cytosolic Fe/S protein in Delta atm1 yeast, substituting for the ABC transporter Atm1p, Similar to Atm1p-deficient yeast, mitochondria of the starik mutant accumulated more nonheme, nonprotein iron than did wild-type organelles, We further show that plant mitochondria contain a putative L-cysteine desulfurase. Taken together, our results suggest that plant mitochondria possess an evolutionarily conserved Fe/S cluster biosynthesis pathway, which is linked to the intracellular iron homeostasis by the function of Atm1p-like ABC transporters.},
  author       = {Kushnir, Sergei and Babiychuk, Elena and Storojenko, Serguei and Davey, Mark W and Papenbrock, Jutta and De Rycke, Riet and Engler, Gilbert and Stephan, Udo W and Lange, Heike and Kispal, Gyula and Lill, Roland and Van Montagu, Marc},
  issn         = {1040-4651},
  journal      = {PLANT CELL},
  keyword      = {EXPRESSION,HIGHER-PLANTS,AMINO-ACID TRANSAMINASES,HOMOLOGS,PROTEIN,YEAST,GENE,THALIANA,SACCHAROMYCES-CEREVISIAE,IRON HOMEOSTASIS},
  language     = {eng},
  number       = {1},
  pages        = {89--100},
  title        = {A mutation of the mitochondrial ABC transporter Sta1 leads to dwarfism and chlorosis in the Arabidopsis mutant starik},
  url          = {http://dx.doi.org/10.1105/tpc.13.1.89},
  volume       = {13},
  year         = {2001},
}

Chicago
Kushnir, Sergei, Elena Babiychuk, Serguei Storojenko, Mark W Davey, Jutta Papenbrock, Riet De Rycke, Gilbert Engler, et al. 2001. “A Mutation of the Mitochondrial ABC Transporter Sta1 Leads to Dwarfism and Chlorosis in the Arabidopsis Mutant Starik.” Plant Cell 13 (1): 89–100.
APA
Kushnir, S., Babiychuk, E., Storojenko, S., Davey, M. W., Papenbrock, J., De Rycke, R., Engler, G., et al. (2001). A mutation of the mitochondrial ABC transporter Sta1 leads to dwarfism and chlorosis in the Arabidopsis mutant starik. PLANT CELL, 13(1), 89–100.
Vancouver
1.
Kushnir S, Babiychuk E, Storojenko S, Davey MW, Papenbrock J, De Rycke R, et al. A mutation of the mitochondrial ABC transporter Sta1 leads to dwarfism and chlorosis in the Arabidopsis mutant starik. PLANT CELL. 2001;13(1):89–100.
MLA
Kushnir, Sergei, Elena Babiychuk, Serguei Storojenko, et al. “A Mutation of the Mitochondrial ABC Transporter Sta1 Leads to Dwarfism and Chlorosis in the Arabidopsis Mutant Starik.” PLANT CELL 13.1 (2001): 89–100. Print.