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Manganese superoxide dismutase can reduce cellular damage mediated by oxygen radicals in transgenic plants

(1991) EMBO JOURNAL. 10(7). p.1723-1732
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Abstract
In plants, environmental adversity often leads to the formation of highly reactive oxygen radicals. Since resistance to such conditions may be correlated with the activity of enzymes involved in oxygen detoxification, we have generated transgenic tobacco plants which express elevated levels of manganese superoxide dismutase (MnSOD) within their chloroplasts or mitochondria. Leaf discs of these plants have been analyzed in conditions in which oxidative stress was generated preferentially within one or the other organelle. It was found that high level overproduction of MnSOD in the corresponding subcellular location could significantly reduce the amount of cellular damage which would normally occur. In contrast, small increases in MnSOD activity were deleterious under some conditions. A generally applicable model correlating the consequences of SOD with the magnitude of its expression is presented.
Keywords
NICOTIANA-TABACUM, OXIDATIVE STRESS, PARAQUAT, PROTEIN TARGETING, TRANSGENIC PLANTS, PHOTOSYNTHETIC ELECTRON-TRANSPORT, CHLOROPHYLL FLUORESCENCE, ESCHERICHIA-COLI, SPINACH-CHLOROPLASTS, LIPID-PEROXIDATION, TRANSFORMED PLANTS, HYDROGEN-PEROXIDE, ELEVATED LEVELS, PHOTOSYSTEM-II, CYTO-TOXICITY

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Citation

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MLA
Bowler, Chris, Luit Slooten, Saskia Vandenbranden, et al. “Manganese Superoxide Dismutase Can Reduce Cellular Damage Mediated by Oxygen Radicals in Transgenic Plants.” EMBO JOURNAL 10.7 (1991): 1723–1732. Print.
APA
Bowler, Chris, Slooten, L., Vandenbranden, S., De Rycke, R., Botterman, J., Sybesma, C., Van Montagu, M., et al. (1991). Manganese superoxide dismutase can reduce cellular damage mediated by oxygen radicals in transgenic plants. EMBO JOURNAL, 10(7), 1723–1732.
Chicago author-date
Bowler, Chris, Luit Slooten, Saskia Vandenbranden, Riet De Rycke, Johan Botterman, Chris Sybesma, Marc Van Montagu, and Dirk Inzé. 1991. “Manganese Superoxide Dismutase Can Reduce Cellular Damage Mediated by Oxygen Radicals in Transgenic Plants.” Embo Journal 10 (7): 1723–1732.
Chicago author-date (all authors)
Bowler, Chris, Luit Slooten, Saskia Vandenbranden, Riet De Rycke, Johan Botterman, Chris Sybesma, Marc Van Montagu, and Dirk Inzé. 1991. “Manganese Superoxide Dismutase Can Reduce Cellular Damage Mediated by Oxygen Radicals in Transgenic Plants.” Embo Journal 10 (7): 1723–1732.
Vancouver
1.
Bowler C, Slooten L, Vandenbranden S, De Rycke R, Botterman J, Sybesma C, et al. Manganese superoxide dismutase can reduce cellular damage mediated by oxygen radicals in transgenic plants. EMBO JOURNAL. 1991;10(7):1723–32.
IEEE
[1]
C. Bowler et al., “Manganese superoxide dismutase can reduce cellular damage mediated by oxygen radicals in transgenic plants,” EMBO JOURNAL, vol. 10, no. 7, pp. 1723–1732, 1991.
@article{346145,
  abstract     = {In plants, environmental adversity often leads to the formation of highly reactive oxygen radicals. Since resistance to such conditions may be correlated with the activity of enzymes involved in oxygen detoxification, we have generated transgenic tobacco plants which express elevated levels of manganese superoxide dismutase (MnSOD) within their chloroplasts or mitochondria. Leaf discs of these plants have been analyzed in conditions in which oxidative stress was generated preferentially within one or the other organelle. It was found that high level overproduction of MnSOD in the corresponding subcellular location could significantly reduce the amount of cellular damage which would normally occur. In contrast, small increases in MnSOD activity were deleterious under some conditions. A generally applicable model correlating the consequences of SOD with the magnitude of its expression is presented.},
  author       = {Bowler, Chris and Slooten, Luit and Vandenbranden, Saskia and De Rycke, Riet and Botterman, Johan and Sybesma, Chris and Van Montagu, Marc and Inzé, Dirk},
  issn         = {0261-4189},
  journal      = {EMBO JOURNAL},
  keywords     = {NICOTIANA-TABACUM,OXIDATIVE STRESS,PARAQUAT,PROTEIN TARGETING,TRANSGENIC PLANTS,PHOTOSYNTHETIC ELECTRON-TRANSPORT,CHLOROPHYLL FLUORESCENCE,ESCHERICHIA-COLI,SPINACH-CHLOROPLASTS,LIPID-PEROXIDATION,TRANSFORMED PLANTS,HYDROGEN-PEROXIDE,ELEVATED LEVELS,PHOTOSYSTEM-II,CYTO-TOXICITY},
  language     = {eng},
  number       = {7},
  pages        = {1723--1732},
  title        = {Manganese superoxide dismutase can reduce cellular damage mediated by oxygen radicals in transgenic plants},
  volume       = {10},
  year         = {1991},
}