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The influence of rTMS over the right dorsolateral prefrontal cortex on intentional set switching

Marie-Anne Vanderhasselt (UGent) , Rudi De Raedt (UGent) , Chris Baeken (UGent) , Lemke Leyman (UGent) and H D'Haenen
(2006) EXPERIMENTAL BRAIN RESEARCH. 172(4). p.561-565
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Organization
Abstract
High frequency (HF) repetitive transcranial magnetic stimulation (rTMS) has an excitatory effect on neurons of a specific brain area. The dorsolateral prefrontal cortex (DLPFC) has been associated with executive functions, such as task set switching. One important experimental paradigm for investigating such higher order cognitive control is the task-switching (TS) paradigm. A TS paradigm requires switching between two conditional response tasks with mutually incompatible response-selection rules. In the present study, the influence of HF rTMS over the right DLPFC in healthy female volunteers on a modified TS paradigm was investigated. As expected, reaction time on cued switching trials decreased significant after rTMS, as compared to non-cued switch trials. No changes emerged after the placebo sham condition. Mood remained unchanged after rTMS. These findings demonstrate the role of the right DLPFC in cued intentional set switch initiation.
Keywords
dorsolateral prefrontal cortex, RTMS, FMRI, CONFLICT, COMPONENTS, STROOP TASK, COGNITIVE CONTROL, TRANSCRANIAL MAGNETIC STIMULATION, ANTERIOR CINGULATE, task switching, executive functioning, intentional set

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Chicago
Vanderhasselt, Marie-Anne, Rudi De Raedt, Chris Baeken, Lemke Leyman, and H D’Haenen. 2006. “The Influence of rTMS over the Right Dorsolateral Prefrontal Cortex on Intentional Set Switching.” Experimental Brain Research 172 (4): 561–565.
APA
Vanderhasselt, M.-A., De Raedt, R., Baeken, C., Leyman, L., & D’Haenen, H. (2006). The influence of rTMS over the right dorsolateral prefrontal cortex on intentional set switching. EXPERIMENTAL BRAIN RESEARCH, 172(4), 561–565.
Vancouver
1.
Vanderhasselt M-A, De Raedt R, Baeken C, Leyman L, D’Haenen H. The influence of rTMS over the right dorsolateral prefrontal cortex on intentional set switching. EXPERIMENTAL BRAIN RESEARCH. 2006;172(4):561–5.
MLA
Vanderhasselt, Marie-Anne, Rudi De Raedt, Chris Baeken, et al. “The Influence of rTMS over the Right Dorsolateral Prefrontal Cortex on Intentional Set Switching.” EXPERIMENTAL BRAIN RESEARCH 172.4 (2006): 561–565. Print.
@article{345749,
  abstract     = {High frequency (HF) repetitive transcranial magnetic stimulation (rTMS) has an excitatory effect on neurons of a specific brain area. The dorsolateral prefrontal cortex (DLPFC) has been associated with executive functions, such as task set switching. One important experimental paradigm for investigating such higher order cognitive control is the task-switching (TS) paradigm. A TS paradigm requires switching between two conditional response tasks with mutually incompatible response-selection rules. In the present study, the influence of HF rTMS over the right DLPFC in healthy female volunteers on a modified TS paradigm was investigated. As expected, reaction time on cued switching trials decreased significant after rTMS, as compared to non-cued switch trials. No changes emerged after the placebo sham condition. Mood remained unchanged after rTMS. These findings demonstrate the role of the right DLPFC in cued intentional set switch initiation.},
  author       = {Vanderhasselt, Marie-Anne and De Raedt, Rudi and Baeken, Chris and Leyman, Lemke and D'Haenen, H},
  issn         = {0014-4819},
  journal      = {EXPERIMENTAL BRAIN RESEARCH},
  keywords     = {dorsolateral prefrontal cortex,RTMS,FMRI,CONFLICT,COMPONENTS,STROOP TASK,COGNITIVE CONTROL,TRANSCRANIAL MAGNETIC STIMULATION,ANTERIOR CINGULATE,task switching,executive functioning,intentional set},
  language     = {eng},
  number       = {4},
  pages        = {561--565},
  title        = {The influence of rTMS over the right dorsolateral prefrontal cortex on intentional set switching},
  url          = {http://dx.doi.org/10.1007/s00221-006-0540-5},
  volume       = {172},
  year         = {2006},
}

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