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Development of mechanically tailored gelatin-chondroitin sulphate hydrogel films

Sandra Van Vlierberghe UGent, Sangram Keshari Samal and Peter Dubruel UGent (2011) Macromolecular Symposia. 309-310. p.173-181
abstract
The aim of the present work was to develop and characterize biohybrid hydrogels containing combinations of gelatin and chondroitin sulphate. Two approaches have been compared. First, physisorption of chondroitin sulphate to gelatin hydrogels was investigated using surface plasmon resonance measurements. Due to the limited interaction between both biopolymers, we developed in a second approach methacrylate-modified chondroitin sulphate hydrogels as such or in combination with methacrylamide-modified gelatin. Rheology measurements indicated that following this approach, mechanically stable hydrogel films could be obtained after UV irradiation in the presence of Irgacure 2959 as UV photo-initiator. When keeping the gelatin concentration and the modification degree constant, an increase in derivatization of the chondroitin sulphate component resulted in a high increase of the storage modulus.
Please use this url to cite or link to this publication:
author
organization
year
type
conference (proceedingsPaper)
publication status
published
subject
keyword
CONTRACTION, EXTRACELLULAR-MATRIX, SCAFFOLDS, MEMBRANE, BINDING, SPONGE, characterization, chondroitin sulphate, hydrogel, gelatin, modification, COLLAGEN-GLYCOSAMINOGLYCAN MATRICES, CROSS-LINKING, IN-VITRO, RHEOLOGICAL PROPERTIES
in
Macromolecular Symposia
editor
A Lendlein and DW Grijpma
volume
309-310
issue title
Advanced polymers in medicine
pages
173 - 181
publisher
Wiley-VCH
place of publication
Weinheim, Germany
conference name
2011 Conference on Advanced Functional Polymers for Medicine (AFPM 2011)
conference location
Enschede, The Netherlands
conference start
2011-06-15
conference end
2011-06-17
Web of Science type
Proceedings Paper
Web of Science id
000305740200021
ISSN
1022-1360
DOI
10.1002/masy.201100030
language
English
UGent publication?
yes
classification
P1
copyright statement
I have transferred the copyright for this publication to the publisher
id
3224385
handle
http://hdl.handle.net/1854/LU-3224385
date created
2013-05-24 16:48:00
date last changed
2017-01-02 09:52:21
@inproceedings{3224385,
  abstract     = {The aim of the present work was to develop and characterize biohybrid hydrogels containing combinations of gelatin and chondroitin sulphate. Two approaches have been compared. First, physisorption of chondroitin sulphate to gelatin hydrogels was investigated using surface plasmon resonance measurements. Due to the limited interaction between both biopolymers, we developed in a second approach methacrylate-modified chondroitin sulphate hydrogels as such or in combination with methacrylamide-modified gelatin. Rheology measurements indicated that following this approach, mechanically stable hydrogel films could be obtained after UV irradiation in the presence of Irgacure 2959 as UV photo-initiator. When keeping the gelatin concentration and the modification degree constant, an increase in derivatization of the chondroitin sulphate component resulted in a high increase of the storage modulus.},
  author       = {Van Vlierberghe, Sandra and Samal, Sangram Keshari and Dubruel, Peter},
  booktitle    = {Macromolecular Symposia},
  editor       = {Lendlein, A and Grijpma, DW},
  issn         = {1022-1360},
  keyword      = {CONTRACTION,EXTRACELLULAR-MATRIX,SCAFFOLDS,MEMBRANE,BINDING,SPONGE,characterization,chondroitin sulphate,hydrogel,gelatin,modification,COLLAGEN-GLYCOSAMINOGLYCAN MATRICES,CROSS-LINKING,IN-VITRO,RHEOLOGICAL PROPERTIES},
  language     = {eng},
  location     = {Enschede, The Netherlands},
  pages        = {173--181},
  publisher    = {Wiley-VCH},
  title        = {Development of mechanically tailored gelatin-chondroitin sulphate hydrogel films},
  url          = {http://dx.doi.org/10.1002/masy.201100030},
  volume       = {309-310},
  year         = {2011},
}

Chicago
Van Vlierberghe, Sandra, Sangram Keshari Samal, and Peter Dubruel. 2011. “Development of Mechanically Tailored Gelatin-chondroitin Sulphate Hydrogel Films.” In Macromolecular Symposia, ed. A Lendlein and DW Grijpma, 309-310:173–181. Weinheim, Germany: Wiley-VCH.
APA
Van Vlierberghe, Sandra, Samal, S. K., & Dubruel, P. (2011). Development of mechanically tailored gelatin-chondroitin sulphate hydrogel films. In A Lendlein & D. Grijpma (Eds.), Macromolecular Symposia (Vol. 309–310, pp. 173–181). Presented at the 2011 Conference on Advanced Functional Polymers for Medicine (AFPM 2011), Weinheim, Germany: Wiley-VCH.
Vancouver
1.
Van Vlierberghe S, Samal SK, Dubruel P. Development of mechanically tailored gelatin-chondroitin sulphate hydrogel films. In: Lendlein A, Grijpma D, editors. Macromolecular Symposia. Weinheim, Germany: Wiley-VCH; 2011. p. 173–81.
MLA
Van Vlierberghe, Sandra, Sangram Keshari Samal, and Peter Dubruel. “Development of Mechanically Tailored Gelatin-chondroitin Sulphate Hydrogel Films.” Macromolecular Symposia. Ed. A Lendlein & DW Grijpma. Vol. 309–310. Weinheim, Germany: Wiley-VCH, 2011. 173–181. Print.