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Parsing the components of the psychomotor syndrome in schizophrenia

Lise Docx, Manuel Morrens, Chris Bervoets, Wouter Hulstijn, Erik Fransen, Marc De Hert, Chris Baeken UGent, Kurt Audenaert UGent and Bernard Sabbe (2012) ACTA PSYCHIATRICA SCANDINAVICA. 126(4). p.256-265
abstract
Objective: Catatonia, extrapyramidal signs, psychomotor slowing, and (motoric) neurological soft signs are well-known psychomotor symptoms in schizophrenia. This study aims at investigating the interrelations between these symptoms. In addition, associations between psychomotor symptoms, clinical symptoms, and cognitive functioning will be studied. Method: An extensive test battery containing psychomotor (Bush Francis Catatonia Rating Scale; St Hans Rating Scale; Salpetriere Retardation Rating Scale; Neurological Evaluation Scale) and clinical (Positive and Negative Syndrome Scale; Calgary Depression Scale) rating scales as well as instrumental psychomotor tests (Line Copying Task; Finger Tapping Task) and cognitive tasks (Symbol Digit Substitution Test; Stroop Colour Word Test; Continuous Performance Test; Letter Number Sequencing) was administered to a sample of 124 patients with schizophrenia or schizoaffective disorder. Results: Correlational analyses showed that two clusters emerge from our data: first, a psychomotor poverty cluster referring to the interrelations between catatonia, parkinsonism, psychomotor slowing, and negative symptoms; second, a cluster containing motoric neurological soft signs, which were found to be correlated with cognitive functioning. Conclusion: Psychomotor abnormalities are highly prevalent phenomena in schizophrenia that have to be considered as a heterogeneous construct. However, longitudinal and neurobiological research is needed to further explore the precise nature of the interrelations found in this study.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
FEATURES CATATONIC SCHIZOPHRENIA, NEUROLOGICAL SOFT SIGNS, DRUG-NAIVE PATIENTS, RATING-SCALE, SPECTRUM DISORDERS, TARDIVE-DYSKINESIA, MOVEMENT-DISORDERS, SYMPTOMS, DEPRESSION, ANTIPSYCHOTICS, neurological signs, catatonia, schizophrenia, psychomotor disorder
journal title
ACTA PSYCHIATRICA SCANDINAVICA
Acta Psychiatr. Scand.
volume
126
issue
4
pages
256 - 265
Web of Science type
Article
Web of Science id
000308872900005
JCR category
PSYCHIATRY
JCR impact factor
4.857 (2012)
JCR rank
12/120 (2012)
JCR quartile
1 (2012)
ISSN
0001-690X
DOI
10.1111/j.1600-0447.2012.01846.x
project
The integrative neuroscience of behavioral control (Neuroscience)
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
3204239
handle
http://hdl.handle.net/1854/LU-3204239
date created
2013-04-30 08:28:31
date last changed
2016-12-19 15:43:15
@article{3204239,
  abstract     = {Objective: Catatonia, extrapyramidal signs, psychomotor slowing, and (motoric) neurological soft signs are well-known psychomotor symptoms in schizophrenia. This study aims at investigating the interrelations between these symptoms. In addition, associations between psychomotor symptoms, clinical symptoms, and cognitive functioning will be studied.
Method: An extensive test battery containing psychomotor (Bush Francis Catatonia Rating Scale; St Hans Rating Scale; Salpetriere Retardation Rating Scale; Neurological Evaluation Scale) and clinical (Positive and Negative Syndrome Scale; Calgary Depression Scale) rating scales as well as instrumental psychomotor tests (Line Copying Task; Finger Tapping Task) and cognitive tasks (Symbol Digit Substitution Test; Stroop Colour Word Test; Continuous Performance Test; Letter Number Sequencing) was administered to a sample of 124 patients with schizophrenia or schizoaffective disorder.
Results: Correlational analyses showed that two clusters emerge from our data: first, a psychomotor poverty cluster referring to the interrelations between catatonia, parkinsonism, psychomotor slowing, and negative symptoms; second, a cluster containing motoric neurological soft signs, which were found to be correlated with cognitive functioning.
Conclusion: Psychomotor abnormalities are highly prevalent phenomena in schizophrenia that have to be considered as a heterogeneous construct. However, longitudinal and neurobiological research is needed to further explore the precise nature of the interrelations found in this study.},
  author       = {Docx, Lise and Morrens, Manuel and Bervoets, Chris and Hulstijn, Wouter and Fransen, Erik and De Hert, Marc and Baeken, Chris and Audenaert, Kurt and Sabbe, Bernard},
  issn         = {0001-690X},
  journal      = {ACTA PSYCHIATRICA SCANDINAVICA},
  keyword      = {FEATURES CATATONIC SCHIZOPHRENIA,NEUROLOGICAL SOFT SIGNS,DRUG-NAIVE PATIENTS,RATING-SCALE,SPECTRUM DISORDERS,TARDIVE-DYSKINESIA,MOVEMENT-DISORDERS,SYMPTOMS,DEPRESSION,ANTIPSYCHOTICS,neurological signs,catatonia,schizophrenia,psychomotor disorder},
  language     = {eng},
  number       = {4},
  pages        = {256--265},
  title        = {Parsing the components of the psychomotor syndrome in schizophrenia},
  url          = {http://dx.doi.org/10.1111/j.1600-0447.2012.01846.x},
  volume       = {126},
  year         = {2012},
}

Chicago
Docx, Lise, Manuel Morrens, Chris Bervoets, Wouter Hulstijn, Erik Fransen, Marc De Hert, Chris Baeken, Kurt Audenaert, and Bernard Sabbe. 2012. “Parsing the Components of the Psychomotor Syndrome in Schizophrenia.” Acta Psychiatrica Scandinavica 126 (4): 256–265.
APA
Docx, L., Morrens, M., Bervoets, C., Hulstijn, W., Fransen, E., De Hert, M., Baeken, C., et al. (2012). Parsing the components of the psychomotor syndrome in schizophrenia. ACTA PSYCHIATRICA SCANDINAVICA, 126(4), 256–265.
Vancouver
1.
Docx L, Morrens M, Bervoets C, Hulstijn W, Fransen E, De Hert M, et al. Parsing the components of the psychomotor syndrome in schizophrenia. ACTA PSYCHIATRICA SCANDINAVICA. 2012;126(4):256–65.
MLA
Docx, Lise, Manuel Morrens, Chris Bervoets, et al. “Parsing the Components of the Psychomotor Syndrome in Schizophrenia.” ACTA PSYCHIATRICA SCANDINAVICA 126.4 (2012): 256–265. Print.