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Exploiting furan’s versatile reactivity in reversible and irreversible orthogonal peptide labeling

Kurt Hoogewijs (UGent) , Dieter Buyst (UGent) , Johan Winne (UGent) , José Martins (UGent) and Annemieke Madder (UGent)
(2013) CHEMICAL COMMUNICATIONS. 49(28). p.2927-2929
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Abstract
A general method for the facile and versatile decoration of peptides is proposed exploiting furan based cycloaddition and electrophilic aromatic substitution reactions. Given the commercial availability of furylalanine derivatives for peptide synthesis, the current work significantly enlarges the toolbox of available methodologies for site specific labeling and conjugation of peptide probes.
Keywords
CROSS-LINKING, DIELS-ALDER, CYCLOADDITIONS, BIOCONJUGATION, FRET-PROBES, LIGATION

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MLA
Hoogewijs, Kurt, et al. “Exploiting Furan’s Versatile Reactivity in Reversible and Irreversible Orthogonal Peptide Labeling.” CHEMICAL COMMUNICATIONS, vol. 49, no. 28, 2013, pp. 2927–29, doi:10.1039/C3CC40588E.
APA
Hoogewijs, K., Buyst, D., Winne, J., Martins, J., & Madder, A. (2013). Exploiting furan’s versatile reactivity in reversible and irreversible orthogonal peptide labeling. CHEMICAL COMMUNICATIONS, 49(28), 2927–2929. https://doi.org/10.1039/C3CC40588E
Chicago author-date
Hoogewijs, Kurt, Dieter Buyst, Johan Winne, José Martins, and Annemieke Madder. 2013. “Exploiting Furan’s Versatile Reactivity in Reversible and Irreversible Orthogonal Peptide Labeling.” CHEMICAL COMMUNICATIONS 49 (28): 2927–29. https://doi.org/10.1039/C3CC40588E.
Chicago author-date (all authors)
Hoogewijs, Kurt, Dieter Buyst, Johan Winne, José Martins, and Annemieke Madder. 2013. “Exploiting Furan’s Versatile Reactivity in Reversible and Irreversible Orthogonal Peptide Labeling.” CHEMICAL COMMUNICATIONS 49 (28): 2927–2929. doi:10.1039/C3CC40588E.
Vancouver
1.
Hoogewijs K, Buyst D, Winne J, Martins J, Madder A. Exploiting furan’s versatile reactivity in reversible and irreversible orthogonal peptide labeling. CHEMICAL COMMUNICATIONS. 2013;49(28):2927–9.
IEEE
[1]
K. Hoogewijs, D. Buyst, J. Winne, J. Martins, and A. Madder, “Exploiting furan’s versatile reactivity in reversible and irreversible orthogonal peptide labeling,” CHEMICAL COMMUNICATIONS, vol. 49, no. 28, pp. 2927–2929, 2013.
@article{3194248,
  abstract     = {{A general method for the facile and versatile decoration of peptides is proposed exploiting furan based cycloaddition and electrophilic aromatic substitution reactions. Given the commercial availability of furylalanine derivatives for peptide synthesis, the current work significantly enlarges the toolbox of available methodologies for site specific labeling and conjugation of peptide probes.}},
  author       = {{Hoogewijs, Kurt and Buyst, Dieter and Winne, Johan and Martins, José and Madder, Annemieke}},
  issn         = {{1359-7345}},
  journal      = {{CHEMICAL COMMUNICATIONS}},
  keywords     = {{CROSS-LINKING,DIELS-ALDER,CYCLOADDITIONS,BIOCONJUGATION,FRET-PROBES,LIGATION}},
  language     = {{eng}},
  number       = {{28}},
  pages        = {{2927--2929}},
  title        = {{Exploiting furan’s versatile reactivity in reversible and irreversible orthogonal peptide labeling}},
  url          = {{http://dx.doi.org/10.1039/C3CC40588E}},
  volume       = {{49}},
  year         = {{2013}},
}

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