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Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors

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Phosphate bioisosteres, 5-Hydroxymethyl pyrimidines, MONOPHOSPHATE KINASE, DRUG DISCOVERY, IN-VITRO, ANALOGS, DNA, REDUCTION, DESIGN, Nucleoside analogues, Inhibitor, Thymidine monophosphate kinase, Mycobacterium tuberculosis

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Citation

Please use this url to cite or link to this publication:

Chicago
Toti, Kiran, Frederick Verbeke, Martijn Risseeuw, Vladimir Frecer, Hélène Munier-Lehmann, and Serge Van Calenbergh. 2013. “Synthesis and Evaluation of 5’-modified Thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium Tuberculosis Thymidylate Kinase Inhibitors.” Bioorganic & Medicinal Chemistry 21 (1): 257–268.
APA
Toti, K., Verbeke, F., Risseeuw, M., Frecer, V., Munier-Lehmann, H., & Van Calenbergh, S. (2013). Synthesis and evaluation of 5’-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, 21(1), 257–268.
Vancouver
1.
Toti K, Verbeke F, Risseeuw M, Frecer V, Munier-Lehmann H, Van Calenbergh S. Synthesis and evaluation of 5’-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY. 2013;21(1):257–68.
MLA
Toti, Kiran, Frederick Verbeke, Martijn Risseeuw, et al. “Synthesis and Evaluation of 5’-modified Thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium Tuberculosis Thymidylate Kinase Inhibitors.” BIOORGANIC & MEDICINAL CHEMISTRY 21.1 (2013): 257–268. Print.
@article{3192256,
  author       = {Toti, Kiran and Verbeke, Frederick and Risseeuw, Martijn and Frecer, Vladimir and Munier-Lehmann, H{\'e}l{\`e}ne and Van Calenbergh, Serge},
  issn         = {0968-0896},
  journal      = {BIOORGANIC \& MEDICINAL CHEMISTRY},
  language     = {eng},
  number       = {1},
  pages        = {257--268},
  title        = {Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors},
  url          = {http://dx.doi.org/10.1016/j.bmc.2012.10.018},
  volume       = {21},
  year         = {2013},
}

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