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Abstract
Total quality in laboratory medicine should be defined as the guarantee that each activity throughout the total testing process is correctly performed, providing valuable medical decision-making and effective patient care. In the past decades, a 10-fold reduction in the analytical error rate has been achieved thanks to improvements in both reliability and standardization of analytical techniques, reagents, and instrumentation. Notable advances in information technology, quality control and quality assurance methods have also assured a valuable contribution for reducing diagnostic errors. Nevertheless, several lines of evidence still suggest that most errors in laboratory diagnostics fall outside the analytical phase, and the pre- and postanalytical steps have been found to be much more vulnerable. This collective paper, which is the logical continuum of the former already published in this journal 2 years ago, provides additional contribution to risk management in the preanalytical phase and is a synopsis of the lectures of the 2nd European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)-Becton Dickinson (BD) European Conference on Preanalytical Phase meeting entitled "Preanalytical quality improvement: in quality we trust" (Zagreb, Croatia, 1-2 March 2013). The leading topics that will be discussed include quality indicators for preanalytical phase, phlebotomy practices for collection of blood gas analysis and pediatric samples, lipemia and blood collection tube interferences, preanalytical requirements of urinalysis, molecular biology hemostasis and platelet testing, as well as indications on best practices for safe blood collection. Auditing of the preanalytical phase by ISO assessors and external quality assessment for preanalytical phase are also discussed.
Keywords
laboratory medicine, preanalytical phase, errors, quality, standardization, PRIMARY-HEALTH-CARE, BLOOD COLLECTION TUBES, LABORATORY MEDICINE, HEMOLYSIS INDEX, CLINICAL LABORATORIES, PATIENT SAFETY, ISO 15189, ERRORS, SAMPLE, DIAGNOSTICS

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Citation

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Chicago
Lippi, Giuseppe, Kathleen Becan-McBride, Darina Behúlová, Raffick A Bowen, Stephen Church, Joris Delanghe, Kjell Grankvist, et al. 2013. “Preanalytical Quality Improvement : in Quality We Trust.” Clinical Chemistry and Laboratory Medicine 51 (1): 229–241.
APA
Lippi, G., Becan-McBride, K., Behúlová, D., Bowen, R. A., Church, S., Delanghe, J., Grankvist, K., et al. (2013). Preanalytical quality improvement : in quality we trust. CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 51(1), 229–241.
Vancouver
1.
Lippi G, Becan-McBride K, Behúlová D, Bowen RA, Church S, Delanghe J, et al. Preanalytical quality improvement : in quality we trust. CLINICAL CHEMISTRY AND LABORATORY MEDICINE. 2013;51(1):229–41.
MLA
Lippi, Giuseppe, Kathleen Becan-McBride, Darina Behúlová, et al. “Preanalytical Quality Improvement : in Quality We Trust.” CLINICAL CHEMISTRY AND LABORATORY MEDICINE 51.1 (2013): 229–241. Print.
@article{3149391,
  abstract     = {Total quality in laboratory medicine should be defined as the guarantee that each activity throughout the total testing process is correctly performed, providing valuable medical decision-making and effective patient care. In the past decades, a 10-fold reduction in the analytical error rate has been achieved thanks to improvements in both reliability and standardization of analytical techniques, reagents, and instrumentation. Notable advances in information technology, quality control and quality assurance methods have also assured a valuable contribution for reducing diagnostic errors. Nevertheless, several lines of evidence still suggest that most errors in laboratory diagnostics fall outside the analytical phase, and the pre- and postanalytical steps have been found to be much more vulnerable. This collective paper, which is the logical continuum of the former already published in this journal 2 years ago, provides additional contribution to risk management in the preanalytical phase and is a synopsis of the lectures of the 2nd European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)-Becton Dickinson (BD) European Conference on Preanalytical Phase meeting entitled {\textacutedbl}Preanalytical quality improvement: in quality we trust{\textacutedbl} (Zagreb, Croatia, 1-2 March 2013). The leading topics that will be discussed include quality indicators for preanalytical phase, phlebotomy practices for collection of blood gas analysis and pediatric samples, lipemia and blood collection tube interferences, preanalytical requirements of urinalysis, molecular biology hemostasis and platelet testing, as well as indications on best practices for safe blood collection. Auditing of the preanalytical phase by ISO assessors and external quality assessment for preanalytical phase are also discussed.},
  author       = {Lippi, Giuseppe and Becan-McBride, Kathleen and Beh{\'u}lov{\'a}, Darina and Bowen, Raffick A and Church, Stephen and Delanghe, Joris and Grankvist, Kjell and Kitchen, Steve and Nybo, Mads and Nauck, Matthias and Nikolac, Nora and Palicka, Vladimir and Plebani, Mario and Sandberg, Sverre and Simundic, Ana-Maria},
  issn         = {1434-6621},
  journal      = {CLINICAL CHEMISTRY AND LABORATORY MEDICINE},
  keyword      = {laboratory medicine,preanalytical phase,errors,quality,standardization,PRIMARY-HEALTH-CARE,BLOOD COLLECTION TUBES,LABORATORY MEDICINE,HEMOLYSIS INDEX,CLINICAL LABORATORIES,PATIENT SAFETY,ISO 15189,ERRORS,SAMPLE,DIAGNOSTICS},
  language     = {eng},
  number       = {1},
  pages        = {229--241},
  title        = {Preanalytical quality improvement : in quality we trust},
  url          = {http://dx.doi.org/10.1515/cclm-2012-0597},
  volume       = {51},
  year         = {2013},
}

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