Advanced search

Tissue Doppler-based measurements of right ventricular function correlate with arterial hypoxemia in horses

Author
Organization
Abstract
Aims: To quantify right ventricular (RV) function by tissue Doppler imaging (TDI) in horses with arterial hypoxemia. Methods: Ten horses with arterial hypoxemia due to RAO (n=6), pneumonia (n=3) or pulmonary haemorrhage (n=1) were included; mean bodyweight 446±123 kg, mean age 11±4 years. The ratio of systolic pulmonary artery to aortic diameter (Pulm/AoD) was measured on a long-axis left ventricular outflow tract image as a marker of pulmonary hypertension. RV systolic and diastolic myocardial velocities, pre-ejection period (PEP) and isovolumic relaxation time (IVRT) were measured by TDI from a right-sided short-axis view at papillary level. Results were compared to a control group of ten healthy horses, 509±58 kg, 10±4 years. Results: Arterial partial oxygen pressure (PaO2) in the hypoxemia group was 57±13 mmHg (reference value >95 mmHg). Pulm/AoD was 1.00±0.09 in the hypoxemia group and 0.78±0.09 in controls (P<0.001). RV myocardial velocities were not significantly different. RV PEP was 116±31 ms in the hypoxemia group compared to 59±18 ms in controls (P<0.001). RV IVRT was 132±35 ms in the hypoxemia group compared to 76±41 ms in controls (P=0.004). Over the 20 horses, Pulm/AoD was positively correlated to RV PEP (0.546; P=0.029) and IVRT (0.641; P=0.003). Pulm/AoD, RV PEP and RV IVRT were negatively correlated to PaO2 (r = -0.855, -0.674, -0.631; P<0.01). Conclusions: TDI detects altered RV function in horses with arterial hypoxemia due to pulmonary disease and might be useful for monitoring effect of treatment.
Keywords
echocardiography, equine, respiratory disease

Citation

Please use this url to cite or link to this publication:

Chicago
Decloedt, Annelies, Nicky Van Der Vekens, Tinne Verheyen, Dominique De Clercq, and Gunther van Loon. 2013. “Tissue Doppler-based Measurements of Right Ventricular Function Correlate with Arterial Hypoxemia in Horses.” In Proceedings of the 6th Congress of the ECEIM : Equine Sports Medicine, 67–67.
APA
Decloedt, Annelies, Van Der Vekens, N., Verheyen, T., De Clercq, D., & van Loon, G. (2013). Tissue Doppler-based measurements of right ventricular function correlate with arterial hypoxemia in horses. Proceedings of the 6th congress of the ECEIM : Equine sports medicine (pp. 67–67). Presented at the 6th Congress of the European College of Equine Internal Medicine (ECEIM).
Vancouver
1.
Decloedt A, Van Der Vekens N, Verheyen T, De Clercq D, van Loon G. Tissue Doppler-based measurements of right ventricular function correlate with arterial hypoxemia in horses. Proceedings of the 6th congress of the ECEIM : Equine sports medicine. 2013. p. 67–67.
MLA
Decloedt, Annelies, Nicky Van Der Vekens, Tinne Verheyen, et al. “Tissue Doppler-based Measurements of Right Ventricular Function Correlate with Arterial Hypoxemia in Horses.” Proceedings of the 6th Congress of the ECEIM : Equine Sports Medicine. 2013. 67–67. Print.
@inproceedings{3131213,
  abstract     = {Aims: To quantify right ventricular (RV) function by tissue Doppler imaging (TDI) in horses with arterial hypoxemia.
Methods: Ten horses with arterial hypoxemia due to RAO (n=6), pneumonia (n=3) or pulmonary haemorrhage (n=1) were included; mean bodyweight 446{\textpm}123 kg, mean age 11{\textpm}4 years. The ratio of systolic pulmonary artery to aortic diameter (Pulm/AoD) was measured on a long-axis left ventricular outflow tract image as a marker of pulmonary hypertension. RV systolic and diastolic myocardial velocities, pre-ejection period (PEP) and isovolumic relaxation time (IVRT) were measured by TDI from a right-sided short-axis view at papillary level. Results were compared to a control group of ten healthy horses, 509{\textpm}58 kg, 10{\textpm}4 years.
Results: Arterial partial oxygen pressure (PaO2) in the hypoxemia group was 57{\textpm}13 mmHg (reference value {\textrangle}95 mmHg). Pulm/AoD was 1.00{\textpm}0.09 in the hypoxemia group and 0.78{\textpm}0.09 in controls (P{\textlangle}0.001). RV myocardial velocities were not significantly different. RV PEP was 116{\textpm}31 ms in the hypoxemia group compared to 59{\textpm}18 ms in controls (P{\textlangle}0.001). RV IVRT was 132{\textpm}35 ms in the hypoxemia group compared to 76{\textpm}41 ms in controls (P=0.004). Over the 20 horses, Pulm/AoD was positively correlated to RV PEP (0.546; P=0.029) and IVRT (0.641; P=0.003). Pulm/AoD, RV PEP and RV IVRT were negatively correlated to PaO2 (r = -0.855, -0.674, -0.631; P{\textlangle}0.01). 
Conclusions: TDI detects altered RV function in horses with arterial hypoxemia due to pulmonary disease and might be useful for monitoring effect of treatment.},
  author       = {Decloedt, Annelies and Van Der Vekens, Nicky and Verheyen, Tinne and De Clercq, Dominique and van Loon, Gunther},
  booktitle    = {Proceedings of the 6th congress of the ECEIM : Equine sports medicine},
  language     = {eng},
  location     = {Le Touquet, France},
  pages        = {67--67},
  title        = {Tissue Doppler-based measurements of right ventricular function correlate with arterial hypoxemia in horses},
  year         = {2013},
}