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Intracranial oligodendroglioma with optic nerve infiltration in a Labrador retriever

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Abstract
A seven-year-old neutered male Labrador retriever was presented with behavioral changes and reduced vision. Neurological examination revealed blindness of the left eye with a positive pupillary light reflex and a decreased mental status. Blood and cerebrospinal fluid analyses showed no abnormalities. MRI revealed a deviant area located in the thalamic, hypothalamic and caudate nuclear regions. Invasion of the left optic nerve was also observed. The dog was euthanized after 38 days of palliative treatment. Necropsy showed a non-encapsulated extruding white lardaceous mass, with a diameter of 2 cm, in the white matter, located in the ventral thalamic region near the chiasma opticum, which extended along the left optic nerve. Histologically, neoplastic cells had a "fried egg" appearance. Immunolabelling for glial fibrillary acidic protein demonstrated the presence of numerous reactive astrocytes. The tumor was diagnosed as a low grade (H) intracranial oligodendroglioma with infiltration of the optic nerve.
Keywords
DOGS, SYSTEM, NEOPLASIA, DIAGNOSIS, BRAIN-TUMORS

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Chicago
Jeuring, Rianne, Karolien Van Driessche, Leslie Bosseler, Cynthia de Vries, An Vanhaesebrouck, Ingrid Gielen, A Oevermann, and Koen Chiers. 2012. “Intracranial Oligodendroglioma with Optic Nerve Infiltration in a Labrador Retriever.” Vlaams Diergeneeskundig Tijdschrift 81 (5): 298–302.
APA
Jeuring, R., Van Driessche, K., Bosseler, L., de Vries, C., Vanhaesebrouck, A., Gielen, I., Oevermann, A., et al. (2012). Intracranial oligodendroglioma with optic nerve infiltration in a Labrador retriever. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, 81(5), 298–302.
Vancouver
1.
Jeuring R, Van Driessche K, Bosseler L, de Vries C, Vanhaesebrouck A, Gielen I, et al. Intracranial oligodendroglioma with optic nerve infiltration in a Labrador retriever. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT. 2012;81(5):298–302.
MLA
Jeuring, Rianne, Karolien Van Driessche, Leslie Bosseler, et al. “Intracranial Oligodendroglioma with Optic Nerve Infiltration in a Labrador Retriever.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT 81.5 (2012): 298–302. Print.
@article{3124268,
  abstract     = {A seven-year-old neutered male Labrador retriever was presented with behavioral changes and reduced vision. Neurological examination revealed blindness of the left eye with a positive pupillary light reflex and a decreased mental status. Blood and cerebrospinal fluid analyses showed no abnormalities. MRI revealed a deviant area located in the thalamic, hypothalamic and caudate nuclear regions. Invasion of the left optic nerve was also observed. The dog was euthanized after 38 days of palliative treatment. Necropsy showed a non-encapsulated extruding white lardaceous mass, with a diameter of 2 cm, in the white matter, located in the ventral thalamic region near the chiasma opticum, which extended along the left optic nerve. Histologically, neoplastic cells had a {\textacutedbl}fried egg{\textacutedbl} appearance. Immunolabelling for glial fibrillary acidic protein demonstrated the presence of numerous reactive astrocytes. The tumor was diagnosed as a low grade (H) intracranial oligodendroglioma with infiltration of the optic nerve.},
  author       = {Jeuring, Rianne and Van Driessche, Karolien and Bosseler, Leslie and de Vries, Cynthia and Vanhaesebrouck, An and Gielen, Ingrid and Oevermann, A and Chiers, Koen},
  issn         = {0303-9021},
  journal      = {VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT},
  keyword      = {DOGS,SYSTEM,NEOPLASIA,DIAGNOSIS,BRAIN-TUMORS},
  language     = {eng},
  number       = {5},
  pages        = {298--302},
  title        = {Intracranial oligodendroglioma with optic nerve infiltration in a Labrador retriever},
  url          = {http://vdt.ugent.be/code/showupload.php?id=752},
  volume       = {81},
  year         = {2012},
}

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