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Vesiclepedia : a compendium for extracellular vesicles with continuous community annotation

(2012) PLOS BIOLOGY. 10(12).
Author
Organization
Abstract
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findings have generated immense interest, along with an exponential increase in molecular data pertaining to EVs. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA, and protein) identified in different classes of EVs from more than 300 independent studies published over the past several years. Even though databases are indispensable resources for the scientific community, recent studies have shown that more than 50% of the databases are not regularly updated. In addition, more than 20% of the database links are inactive. To prevent such database and link decay, we have initiated a continuous community annotation project with the active involvement of EV researchers. The EV research community can set a gold standard in data sharing with Vesiclepedia, which could evolve as a primary resource for the field.
Keywords
UPDATE, HUMAN PROTEINPEDIA, BIOGENESIS, RNA, MICROVESICLES, CELLS, BREAST-MILK, DELIVERY-SYSTEM, EXOSOMAL PROTEINS, URL DECAY

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Citation

Please use this url to cite or link to this publication:

MLA
Kalra, Hina, Richard J Simpson, Hong Ji, et al. “Vesiclepedia : a Compendium for Extracellular Vesicles with Continuous Community Annotation.” PLOS BIOLOGY 2012 : n. pag. Print.
APA
Kalra, H., Simpson, R. J., Ji, H., Aikawa, E., Altevogt, P., Askenase, P., Bond, V. C., et al. (2012). Vesiclepedia : a compendium for extracellular vesicles with continuous community annotation. PLOS BIOLOGY.
Chicago author-date
Kalra, Hina, Richard J Simpson, Hong Ji, Elena Aikawa, Peter Altevogt, Philip Askenase, Vincent C Bond, et al. 2012. “Vesiclepedia : a Compendium for Extracellular Vesicles with Continuous Community Annotation.” Plos Biology.
Chicago author-date (all authors)
Kalra, Hina, Richard J Simpson, Hong Ji, Elena Aikawa, Peter Altevogt, Philip Askenase, Vincent C Bond, Francesc E Borràs, Xandra Breakefield, Vivian Budnik, Edit Buzas, Giovanni Camussi, Aled Clayton, Emanuele Cocucci, Juan M Falcon-Perez, Susanne Gabrielsson, Yong Song Gho, Dwijendra Gupta, HC Harsha, An Hendrix, Andrew F Hill, Jameel M Inal, Guido Jenster, Eva-Maria Krämer-Albers, Sai Kiang Lim, Alicia Llorente, Jan Lötvall, Antonio Marcilla, Lucia Mincheva-Nilsson, Irina Nazarenko, Rienk Nieuwland, Esther NM Nolte-’t Hoen, Akhilesh Pandey, Tushar Patel, Melissa G Piper, Stefano Pluchino, TS Keshava Prasad, Lawrence Rajendran, Graca Raposo, Michel Record, Gavin E Reid, Francisco Sánchez-Madrid, Raymond M Schiffelers, Pia Siljander, Allan Stensballe, Willem Stoorvogel, Douglas Taylor, Clotilde Thery, Hadi Valadi, Bas WM van Balkom, Jésus Vázquez, Michel Vidal, Marca HM Wauben, María Yáñez-Mó, Margot Zoeller, and Suresh Mathivanan. 2012. “Vesiclepedia : a Compendium for Extracellular Vesicles with Continuous Community Annotation.” Plos Biology.
Vancouver
1.
Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, et al. Vesiclepedia : a compendium for extracellular vesicles with continuous community annotation. PLOS BIOLOGY. 2012.
IEEE
[1]
H. Kalra et al., “Vesiclepedia : a compendium for extracellular vesicles with continuous community annotation,” PLOS BIOLOGY, vol. 10, no. 12. 2012.
@misc{3123763,
  abstract     = {Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findings have generated immense interest, along with an exponential increase in molecular data pertaining to EVs. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA, and protein) identified in different classes of EVs from more than 300 independent studies published over the past several years. Even though databases are indispensable resources for the scientific community, recent studies have shown that more than 50% of the databases are not regularly updated. In addition, more than 20% of the database links are inactive. To prevent such database and link decay, we have initiated a continuous community annotation project with the active involvement of EV researchers. The EV research community can set a gold standard in data sharing with Vesiclepedia, which could evolve as a primary resource for the field.},
  articleno    = {e1001450},
  author       = {Kalra, Hina and Simpson, Richard J and Ji, Hong and Aikawa, Elena and Altevogt, Peter and Askenase, Philip and Bond, Vincent C and Borràs, Francesc E and Breakefield, Xandra and Budnik, Vivian and Buzas, Edit and Camussi, Giovanni and Clayton, Aled and Cocucci, Emanuele and Falcon-Perez, Juan M and Gabrielsson, Susanne and Gho, Yong Song and Gupta, Dwijendra and Harsha, HC and Hendrix, An and Hill, Andrew F and Inal, Jameel M and Jenster, Guido and Krämer-Albers, Eva-Maria and Lim, Sai Kiang and Llorente, Alicia and Lötvall, Jan and Marcilla, Antonio and Mincheva-Nilsson, Lucia and Nazarenko, Irina and Nieuwland, Rienk and Nolte-'t Hoen, Esther NM and Pandey, Akhilesh and Patel, Tushar and Piper, Melissa G and Pluchino, Stefano and Prasad, TS Keshava and Rajendran, Lawrence and Raposo, Graca and Record, Michel and Reid, Gavin E and Sánchez-Madrid, Francisco and Schiffelers, Raymond M and Siljander, Pia and Stensballe, Allan and Stoorvogel, Willem and Taylor, Douglas and Thery, Clotilde and Valadi, Hadi and van Balkom, Bas WM and Vázquez, Jésus and Vidal, Michel and Wauben, Marca HM and Yáñez-Mó, María and Zoeller, Margot and Mathivanan, Suresh},
  issn         = {1545-7885},
  keywords     = {UPDATE,HUMAN PROTEINPEDIA,BIOGENESIS,RNA,MICROVESICLES,CELLS,BREAST-MILK,DELIVERY-SYSTEM,EXOSOMAL PROTEINS,URL DECAY},
  language     = {eng},
  number       = {12},
  pages        = {5},
  series       = {PLOS BIOLOGY},
  title        = {Vesiclepedia : a compendium for extracellular vesicles with continuous community annotation},
  url          = {http://dx.doi.org/10.1371/journal.pbio.1001450},
  volume       = {10},
  year         = {2012},
}

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