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Real-time tracking of memory formation in the human rhinal cortex and hippocampus

(1999) SCIENCE. 285(5433). p.1582-1585
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Abstract
A fundamental question about human memory is which brain structures are involved, and when, in transforming experiences into memories. This experiment sought to identify neural correlates of memory formation with the use of intracerebral electrodes implanted in the brains of patients with temporal Lobe epilepsy. Event-related potentials (ERPs) were recorded directly from the medial temporal Lobe (MTL) as the patients studied single words. ERPs elicited by words subsequently recalled in a memory test were contrasted with ERPs elicited by unrecalled words. Memory formation was associated with distinct but interrelated ERP differences within the rhinal cortex and the hippocampus, which arose after about 300 and 500 milliseconds, respectively. These findings suggest that declarative memory formation is dissociable into subprocesses and sequentially organized within the MTL.
Keywords
EVENT-RELATED POTENTIALS, MEDIAL TEMPORAL-LOBE, EPISODIC MEMORY, ANTIEPILEPTIC DRUGS, SEMANTIC MEMORY, BRAIN ACTIVITY, SYSTEM, WORDS, ORGANIZATION, RECOGNITION

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Citation

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Chicago
Fernández, Guillén, Arndt Effern, Thomas Grunwald, Nico Pezer, Klaus Lehnertz, Matthias Dümpelmann, Dirk Van Roost, and Christian E Elger. 1999. “Real-time Tracking of Memory Formation in the Human Rhinal Cortex and Hippocampus.” Science 285 (5433): 1582–1585.
APA
Fernández, G., Effern, A., Grunwald, T., Pezer, N., Lehnertz, K., Dümpelmann, M., Van Roost, D., et al. (1999). Real-time tracking of memory formation in the human rhinal cortex and hippocampus. SCIENCE, 285(5433), 1582–1585.
Vancouver
1.
Fernández G, Effern A, Grunwald T, Pezer N, Lehnertz K, Dümpelmann M, et al. Real-time tracking of memory formation in the human rhinal cortex and hippocampus. SCIENCE. 1999;285(5433):1582–5.
MLA
Fernández, Guillén, Arndt Effern, Thomas Grunwald, et al. “Real-time Tracking of Memory Formation in the Human Rhinal Cortex and Hippocampus.” SCIENCE 285.5433 (1999): 1582–1585. Print.
@article{3100844,
  abstract     = {A fundamental question about human memory is which brain structures are involved, and when, in transforming experiences into memories. This experiment sought to identify neural correlates of memory formation with the use of intracerebral electrodes implanted in the brains of patients with temporal Lobe epilepsy. Event-related potentials (ERPs) were recorded directly from the medial temporal Lobe (MTL) as the patients studied single words. ERPs elicited by words subsequently recalled in a memory test were contrasted with ERPs elicited by unrecalled words. Memory formation was associated with distinct but interrelated ERP differences within the rhinal cortex and the hippocampus, which arose after about 300 and 500 milliseconds, respectively. These findings suggest that declarative memory formation is dissociable into subprocesses and sequentially organized within the MTL.},
  author       = {Fernández, Guillén and Effern, Arndt and Grunwald, Thomas and Pezer, Nico and Lehnertz, Klaus and Dümpelmann, Matthias and Van Roost, Dirk and Elger, Christian E},
  issn         = {0036-8075},
  journal      = {SCIENCE},
  keywords     = {EVENT-RELATED POTENTIALS,MEDIAL TEMPORAL-LOBE,EPISODIC MEMORY,ANTIEPILEPTIC DRUGS,SEMANTIC MEMORY,BRAIN ACTIVITY,SYSTEM,WORDS,ORGANIZATION,RECOGNITION},
  language     = {eng},
  number       = {5433},
  pages        = {1582--1585},
  title        = {Real-time tracking of memory formation in the human rhinal cortex and hippocampus},
  url          = {http://dx.doi.org/10.1126/science.285.5433.1582},
  volume       = {285},
  year         = {1999},
}

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