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Recombinant human thyrotropin in thyroid cancer and hypopituitarism due to sella metastasis

(1999) THYROID. 9(12). p.1253-1256
Author
Organization
Abstract
We present a patient with thyroid cancer and hypopituitarism who required recombinant human thyrotropin (rhTSH) for I-131 Scanning with respect to subsequent therapy. The thyroid cancer had been unknown until central neurological symptoms developed, leading to the diagnosis of a huge metastasis to the sella that was the only manifestation of metastatic spread. The failure to generate endogenous thyrotropin (TSH) was overcome by the use of rhTSH for performing a I-131 test. Unfortunately, the I-131 uptake was not sufficient for therapy. This subject is the first reported case who required the application of rhTSH due to a single thyroid cancer metastasis in the sella region with secondary failure to generate endogenous TSH.
Keywords
I-131, PITUITARY, WITHDRAWAL, HORMONE, CARCINOMA

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Citation

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MLA
Risse, Jörn H., et al. “Recombinant Human Thyrotropin in Thyroid Cancer and Hypopituitarism Due to Sella Metastasis.” THYROID, vol. 9, no. 12, 1999, pp. 1253–56.
APA
Risse, J. H., Grünwald, F., Bender, H., Schüller, H., Van Roost, D., & Biersack, H.-J. (1999). Recombinant human thyrotropin in thyroid cancer and hypopituitarism due to sella metastasis. THYROID, 9(12), 1253–1256.
Chicago author-date
Risse, Jörn H, Frank Grünwald, Hans Bender, Heinrich Schüller, Dirk Van Roost, and Hans-Jürgen Biersack. 1999. “Recombinant Human Thyrotropin in Thyroid Cancer and Hypopituitarism Due to Sella Metastasis.” THYROID 9 (12): 1253–56.
Chicago author-date (all authors)
Risse, Jörn H, Frank Grünwald, Hans Bender, Heinrich Schüller, Dirk Van Roost, and Hans-Jürgen Biersack. 1999. “Recombinant Human Thyrotropin in Thyroid Cancer and Hypopituitarism Due to Sella Metastasis.” THYROID 9 (12): 1253–1256.
Vancouver
1.
Risse JH, Grünwald F, Bender H, Schüller H, Van Roost D, Biersack H-J. Recombinant human thyrotropin in thyroid cancer and hypopituitarism due to sella metastasis. THYROID. 1999;9(12):1253–6.
IEEE
[1]
J. H. Risse, F. Grünwald, H. Bender, H. Schüller, D. Van Roost, and H.-J. Biersack, “Recombinant human thyrotropin in thyroid cancer and hypopituitarism due to sella metastasis,” THYROID, vol. 9, no. 12, pp. 1253–1256, 1999.
@article{3100823,
  abstract     = {We present a patient with thyroid cancer and hypopituitarism who required recombinant human thyrotropin (rhTSH) for I-131 Scanning with respect to subsequent therapy. The thyroid cancer had been unknown until central neurological symptoms developed, leading to the diagnosis of a huge metastasis to the sella that was the only manifestation of metastatic spread. The failure to generate endogenous thyrotropin (TSH) was overcome by the use of rhTSH for performing a I-131 test. Unfortunately, the I-131 uptake was not sufficient for therapy. This subject is the first reported case who required the application of rhTSH due to a single thyroid cancer metastasis in the sella region with secondary failure to generate endogenous TSH.},
  author       = {Risse, Jörn H and Grünwald, Frank and Bender, Hans and Schüller, Heinrich and Van Roost, Dirk and Biersack, Hans-Jürgen},
  issn         = {1050-7256},
  journal      = {THYROID},
  keywords     = {I-131,PITUITARY,WITHDRAWAL,HORMONE,CARCINOMA},
  language     = {eng},
  number       = {12},
  pages        = {1253--1256},
  title        = {Recombinant human thyrotropin in thyroid cancer and hypopituitarism due to sella metastasis},
  url          = {http://dx.doi.org/10.1089/thy.1999.9.1253},
  volume       = {9},
  year         = {1999},
}

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