Ghent University Academic Bibliography

Advanced

Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol

Benjamin Horemans, Cedric Van Holsbeke UGent, Wim Vos, Larysa Darchuk, Velibor Novakovic, Angel Fontan, Jan De Backer, René Van Grieken, Wilfried De Backer and Karolien De Wael (2012) ENVIRONMENTAL SCIENCE & TECHNOLOGY. 46(21). p.12162-12169
abstract
Urban atmospheres in modern cities carry characteristic mixtures of particulate pollution which are potentially aggravating for chronic respiratory patients (CRP). Although air quality surveys can be detailed, the obtained information is not always useful to evaluate human health effects. This paper presents a novel approach to estimate particle deposition rates in airways of CRP, based on real air pollution data. By combining computational fluid dynamics with physical-chemical characteristics of particulate pollution, deposition rates are estimated for particles of different toxicological relevance, that is, minerals, iron oxides, sea salts, ammonium salts, and carbonaceous particles. Also, it enables some qualitative evaluation of the spatial, temporal, and patient specific effects on the particle dose upon exposure to the urban atmosphere. Results show how heavy traffic conditions increases the deposition of anthropogenic particles in the trachea and lungs of respiratory patients (here, +0.28 and +1.5 μg·h–1, respectively). In addition, local and synoptic meteorological conditions were found to have a strong effect on the overall dose. However, the pathology and age of the patient was found to be more crucial, with highest deposition rates for toxic particles in adults with a mild anomaly, followed by mild asthmatic children and adults with severe respiratory dysfunctions (7, 5, and 3 μg·h–1, respectively).
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
COMPUTATIONAL FLUID-DYNAMICS, AIRBORNE PARTICULATE MATTER, AIR-POLLUTION, CHEMICAL-COMPOSITION, ULTRAFINE PARTICLES, OFFICE ENVIRONMENTS, OXIDANT GENERATION, LUNG DEPOSITION, BELGIUM, DISEASE
journal title
ENVIRONMENTAL SCIENCE & TECHNOLOGY
Environ. Sci. Technol.
volume
46
issue
21
pages
12162 - 12169
Web of Science type
Article
Web of Science id
000310665000082
JCR category
ENVIRONMENTAL SCIENCES
JCR impact factor
5.257 (2012)
JCR rank
7/209 (2012)
JCR quartile
1 (2012)
ISSN
0013-936X
DOI
10.1021/es302755s
language
English
UGent publication?
no
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
3048971
handle
http://hdl.handle.net/1854/LU-3048971
date created
2012-11-08 10:34:17
date last changed
2013-07-02 14:39:07
@article{3048971,
  abstract     = {Urban atmospheres in modern cities carry characteristic mixtures of particulate pollution which are potentially aggravating for chronic respiratory patients (CRP). Although air quality surveys can be detailed, the obtained information is not always useful to evaluate human health effects. This paper presents a novel approach to estimate particle deposition rates in airways of CRP, based on real air pollution data. By combining computational fluid dynamics with physical-chemical characteristics of particulate pollution, deposition rates are estimated for particles of different toxicological relevance, that is, minerals, iron oxides, sea salts, ammonium salts, and carbonaceous particles. Also, it enables some qualitative evaluation of the spatial, temporal, and patient specific effects on the particle dose upon exposure to the urban atmosphere. Results show how heavy traffic conditions increases the deposition of anthropogenic particles in the trachea and lungs of respiratory patients (here, +0.28 and +1.5 \ensuremath{\mu}g{\textperiodcentered}h--1, respectively). In addition, local and synoptic meteorological conditions were found to have a strong effect on the overall dose. However, the pathology and age of the patient was found to be more crucial, with highest deposition rates for toxic particles in adults with a mild anomaly, followed by mild asthmatic children and adults with severe respiratory dysfunctions (7, 5, and 3 \ensuremath{\mu}g{\textperiodcentered}h--1, respectively).},
  author       = {Horemans, Benjamin and Van Holsbeke, Cedric and Vos, Wim and Darchuk, Larysa and Novakovic, Velibor and Fontan, Angel and De Backer, Jan and Van Grieken, Ren{\'e} and De Backer, Wilfried and De Wael, Karolien},
  issn         = {0013-936X},
  journal      = {ENVIRONMENTAL SCIENCE \& TECHNOLOGY},
  keyword      = {COMPUTATIONAL FLUID-DYNAMICS,AIRBORNE PARTICULATE MATTER,AIR-POLLUTION,CHEMICAL-COMPOSITION,ULTRAFINE PARTICLES,OFFICE ENVIRONMENTS,OXIDANT GENERATION,LUNG DEPOSITION,BELGIUM,DISEASE},
  language     = {eng},
  number       = {21},
  pages        = {12162--12169},
  title        = {Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol},
  url          = {http://dx.doi.org/10.1021/es302755s},
  volume       = {46},
  year         = {2012},
}

Chicago
Horemans, Benjamin, Cedric Van Holsbeke, Wim Vos, Larysa Darchuk, Velibor Novakovic, Angel Fontan, Jan De Backer, René Van Grieken, Wilfried De Backer, and Karolien De Wael. 2012. “Particle Deposition in Airways of Chronic Respiratory Patients Exposed to an Urban Aerosol.” Environmental Science & Technology 46 (21): 12162–12169.
APA
Horemans, Benjamin, Van Holsbeke, C., Vos, W., Darchuk, L., Novakovic, V., Fontan, A., De Backer, J., et al. (2012). Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 46(21), 12162–12169.
Vancouver
1.
Horemans B, Van Holsbeke C, Vos W, Darchuk L, Novakovic V, Fontan A, et al. Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol. ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2012;46(21):12162–9.
MLA
Horemans, Benjamin, Cedric Van Holsbeke, Wim Vos, et al. “Particle Deposition in Airways of Chronic Respiratory Patients Exposed to an Urban Aerosol.” ENVIRONMENTAL SCIENCE & TECHNOLOGY 46.21 (2012): 12162–12169. Print.