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Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol

(2012) ENVIRONMENTAL SCIENCE & TECHNOLOGY. 46(21). p.12162-12169
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Abstract
Urban atmospheres in modern cities carry characteristic mixtures of particulate pollution which are potentially aggravating for chronic respiratory patients (CRP). Although air quality surveys can be detailed, the obtained information is not always useful to evaluate human health effects. This paper presents a novel approach to estimate particle deposition rates in airways of CRP, based on real air pollution data. By combining computational fluid dynamics with physical-chemical characteristics of particulate pollution, deposition rates are estimated for particles of different toxicological relevance, that is, minerals, iron oxides, sea salts, ammonium salts, and carbonaceous particles. Also, it enables some qualitative evaluation of the spatial, temporal, and patient specific effects on the particle dose upon exposure to the urban atmosphere. Results show how heavy traffic conditions increases the deposition of anthropogenic particles in the trachea and lungs of respiratory patients (here, +0.28 and +1.5 μg·h–1, respectively). In addition, local and synoptic meteorological conditions were found to have a strong effect on the overall dose. However, the pathology and age of the patient was found to be more crucial, with highest deposition rates for toxic particles in adults with a mild anomaly, followed by mild asthmatic children and adults with severe respiratory dysfunctions (7, 5, and 3 μg·h–1, respectively).
Keywords
COMPUTATIONAL FLUID-DYNAMICS, AIRBORNE PARTICULATE MATTER, AIR-POLLUTION, CHEMICAL-COMPOSITION, ULTRAFINE PARTICLES, OFFICE ENVIRONMENTS, OXIDANT GENERATION, LUNG DEPOSITION, BELGIUM, DISEASE

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MLA
Horemans, Benjamin, Cedric Van Holsbeke, Wim Vos, et al. “Particle Deposition in Airways of Chronic Respiratory Patients Exposed to an Urban Aerosol.” ENVIRONMENTAL SCIENCE & TECHNOLOGY 46.21 (2012): 12162–12169. Print.
APA
Horemans, Benjamin, Van Holsbeke, C., Vos, W., Darchuk, L., Novakovic, V., Fontan, A., De Backer, J., et al. (2012). Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 46(21), 12162–12169.
Chicago author-date
Horemans, Benjamin, Cedric Van Holsbeke, Wim Vos, Larysa Darchuk, Velibor Novakovic, Angel Fontan, Jan De Backer, René Van Grieken, Wilfried De Backer, and Karolien De Wael. 2012. “Particle Deposition in Airways of Chronic Respiratory Patients Exposed to an Urban Aerosol.” Environmental Science & Technology 46 (21): 12162–12169.
Chicago author-date (all authors)
Horemans, Benjamin, Cedric Van Holsbeke, Wim Vos, Larysa Darchuk, Velibor Novakovic, Angel Fontan, Jan De Backer, René Van Grieken, Wilfried De Backer, and Karolien De Wael. 2012. “Particle Deposition in Airways of Chronic Respiratory Patients Exposed to an Urban Aerosol.” Environmental Science & Technology 46 (21): 12162–12169.
Vancouver
1.
Horemans B, Van Holsbeke C, Vos W, Darchuk L, Novakovic V, Fontan A, et al. Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol. ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2012;46(21):12162–9.
IEEE
[1]
B. Horemans et al., “Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol,” ENVIRONMENTAL SCIENCE & TECHNOLOGY, vol. 46, no. 21, pp. 12162–12169, 2012.
@article{3048971,
  abstract     = {Urban atmospheres in modern cities carry characteristic mixtures of particulate pollution which are potentially aggravating for chronic respiratory patients (CRP). Although air quality surveys can be detailed, the obtained information is not always useful to evaluate human health effects. This paper presents a novel approach to estimate particle deposition rates in airways of CRP, based on real air pollution data. By combining computational fluid dynamics with physical-chemical characteristics of particulate pollution, deposition rates are estimated for particles of different toxicological relevance, that is, minerals, iron oxides, sea salts, ammonium salts, and carbonaceous particles. Also, it enables some qualitative evaluation of the spatial, temporal, and patient specific effects on the particle dose upon exposure to the urban atmosphere. Results show how heavy traffic conditions increases the deposition of anthropogenic particles in the trachea and lungs of respiratory patients (here, +0.28 and +1.5 μg·h–1, respectively). In addition, local and synoptic meteorological conditions were found to have a strong effect on the overall dose. However, the pathology and age of the patient was found to be more crucial, with highest deposition rates for toxic particles in adults with a mild anomaly, followed by mild asthmatic children and adults with severe respiratory dysfunctions (7, 5, and 3 μg·h–1, respectively).},
  author       = {Horemans, Benjamin and Van Holsbeke, Cedric and Vos, Wim and Darchuk, Larysa and Novakovic, Velibor and Fontan, Angel and De Backer, Jan and Van Grieken, René and De Backer, Wilfried and De Wael, Karolien},
  issn         = {0013-936X},
  journal      = {ENVIRONMENTAL SCIENCE & TECHNOLOGY},
  keywords     = {COMPUTATIONAL FLUID-DYNAMICS,AIRBORNE PARTICULATE MATTER,AIR-POLLUTION,CHEMICAL-COMPOSITION,ULTRAFINE PARTICLES,OFFICE ENVIRONMENTS,OXIDANT GENERATION,LUNG DEPOSITION,BELGIUM,DISEASE},
  language     = {eng},
  number       = {21},
  pages        = {12162--12169},
  title        = {Particle deposition in airways of chronic respiratory patients exposed to an urban aerosol},
  url          = {http://dx.doi.org/10.1021/es302755s},
  volume       = {46},
  year         = {2012},
}

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