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Accumulating evidence indicates that ER-stress-activated pathways, e.g. the unfolded protein response (UPR), lead to activation of various inflammatory processes, such as the acute-phase response (APR) and those instigated by transcriptional factors like NF-κB and AP-1. ER stress-mediated inflammation has been found to be associated with several diseases, such as obesity, type 2 diabetes, intestinal bowel disease and cancer. The role of ER stress-mediated inflammation is not straightforward as it can vary from disease-promoting/supporting to disease-controlling depending upon the cell type or disease in focus. This makes therapeutic targeting of ER stress-mediated inflammation very challenging and tough. In this chapter, we discuss the biology of ER stress-induced inflammation, its role in various diseases, and the possibility of targeting it for therapeutic purposes.

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Chicago
Garg, Abhsihek D, Agnieszka Kaczmarek, Dmitri Krysko, and Peter Vandenabeele. 2012. “ER Stress and Inflammation.” In Endoplasmic Reticulum Stress in Health and Disease, ed. Patrizia Agostinis and Afshin Samali, 257–279. Dordrecht, The Netherlands: Springer.
APA
Garg, Abhsihek D, Kaczmarek, A., Krysko, D., & Vandenabeele, P. (2012). ER stress and inflammation. In P. Agostinis & A. Samali (Eds.), Endoplasmic reticulum stress in health and disease (pp. 257–279). Dordrecht, The Netherlands: Springer.
Vancouver
1.
Garg AD, Kaczmarek A, Krysko D, Vandenabeele P. ER stress and inflammation. In: Agostinis P, Samali A, editors. Endoplasmic reticulum stress in health and disease. Dordrecht, The Netherlands: Springer; 2012. p. 257–79.
MLA
Garg, Abhsihek D, Agnieszka Kaczmarek, Dmitri Krysko, et al. “ER Stress and Inflammation.” Endoplasmic Reticulum Stress in Health and Disease. Ed. Patrizia Agostinis & Afshin Samali. Dordrecht, The Netherlands: Springer, 2012. 257–279. Print.
@incollection{3039441,
  abstract     = {Accumulating evidence indicates that ER-stress-activated pathways, e.g. the unfolded protein response (UPR), lead to activation of various inflammatory processes, such as the acute-phase response (APR) and those instigated by transcriptional factors like NF-\ensuremath{\kappa}B and AP-1. ER stress-mediated inflammation has been found to be associated with several diseases, such as obesity, type 2 diabetes, intestinal bowel disease and cancer. The role of ER stress-mediated inflammation is not straightforward as it can vary from disease-promoting/supporting to disease-controlling depending upon the cell type or disease in focus. This makes therapeutic targeting of ER stress-mediated inflammation very challenging and tough. In this chapter, we discuss the biology of ER stress-induced inflammation, its role in various diseases, and the possibility of targeting it for therapeutic purposes.},
  author       = {Garg, Abhsihek D and Kaczmarek, Agnieszka and Krysko, Dmitri and Vandenabeele, Peter},
  booktitle    = {Endoplasmic reticulum stress in health and disease},
  editor       = {Agostinis, Patrizia and Samali, Afshin},
  isbn         = {9789400743502},
  language     = {eng},
  pages        = {257--279},
  publisher    = {Springer},
  title        = {ER stress and inflammation},
  url          = {http://dx.doi.org/10.1007/978-94-007-4351-9\_11},
  year         = {2012},
}

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